Crowley, Denise

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

Olive, K. P., Tuveson, D. A., Ruhe, Z. C., Yin, B., Willis, N. A., Bronson, R. T., Crowley, D., & Jacks, T. (2004) · Cell

Cancer-related Molecular PathwaysChromatin Remodeling and Cancer

Cited by 1,308

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

Johnson, L., Mercer, K., Greenbaum, D., Bronson, R. T., Crowley, D., Tuveson, D. A., & Jacks, T. (2001) · Nature

Protein Kinase Regulation and GTPase SignalingCancer-related Molecular Pathways

Cited by 1,179

Endogenous oncogenic K-rasG12D stimulates proliferation and widespread neoplastic and developmental defects

Tuveson, D. A., Shaw, A. T., Willis, N. A., Silver, D. P., Jackson, E. L., Chang, S., Mercer, K. L., Grochow, R., Hock, H., Crowley, D., et al. (2004) · Cancer Cell

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 798

CRISPR-mediated direct mutation of cancer genes in the mouse liver

Xue, W., Chen, S., Yin, H., Tammela, T., Papagiannakopoulos, T., Joshi, N. S., Cai, W., Yang, G., Bronson, R., Crowley, D. G., et al. (2014) · Nature

CRISPR and Genetic EngineeringCancer Genomics and Diagnostics

Cited by 776

The Differential Effects of Mutant p53 Alleles on Advanced Murine Lung Cancer

Jackson, E. L., Olive, K. P., Tuveson, D. A., Bronson, R., Crowley, D., Brown, M., & Jacks, T. (2005) · Cancer Research

Cancer-related Molecular PathwaysLung Cancer Research Studies

Cited by 553

Suppression of lung adenocarcinoma progression by Nkx2-1

Winslow, M. M., Dayton, T. L., Verhaak, R. G. W., Kim-Kiselak, C., Snyder, E. L., Feldser, D. M., Hubbard, D. D., DuPage, M. J., Whittaker, C. A., Hoersch, S., et al. (2011) · Nature

Cancer Cells and MetastasisMechanisms of cancer metastasis

Cited by 467

Mutation of E2f-1 Suppresses Apoptosis and Inappropriate S Phase Entry and Extends Survival of Rb-Deficient Mouse Embryos

Tsai, K. Y., Hu, Y., Macleod, K. F., Crowley, D., Yamasaki, L., & Jacks, T. (1998) · Molecular Cell

Cancer-related Molecular PathwaysDevelopmental Biology and Gene Regulation

Cited by 372

Multiple cardiovascular defects caused by the absence of alternatively spliced segments of fibronectin

Astrof, S., Crowley, D., & Hynes, R. O. (2007) · Developmental Biology

RNA Research and SplicingCell Adhesion Molecules Research

Cited by 136

Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis

Shaw, A. T., Meissner, A., Dowdle, J. A., Crowley, D., Magendantz, M., Ouyang, C., Parisi, T., Rajagopal, J., Blank, L. J., Bronson, R. T., et al. (2007) · Genes & Development

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 131