DeSimone, Joseph

5-Azacytidine Selectively Increases γ-Globin Synthesis in a Patient with β+Thalassemia

Ley, T. J., DeSimone, J., Anagnou, N. P., Keller, G. H., Humphries, R. K., Turner, P. H., Young, N. S., Heller, P., & Nienhuis, A. W. (1982) · New England Journal of Medicine

Hemoglobinopathies and Related DisordersHemoglobin structure and function

Cited by 490

Effects of 5-aza-2′-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease

Saunthararajah, Y., Hillery, C. A., Lavelle, D., Molokie, R., Dorn, L., Bressler, L., Gavazova, S., Chen, Y.-H., Hoffman, R., & DeSimone, J. (2003) · Blood

Hemoglobinopathies and Related DisordersBlood groups and transfusion

Cited by 277

Modification of hematopoietic stem cell fate by 5aza 2′deoxycytidine and trichostatin A.

Milhem, M., Mahmud, N., Lavelle, D., Araki, H., DeSimone, J., Saunthararajah, Y., & Hoffman, R. (2004) · Blood

Hematopoietic Stem Cell TransplantationEpigenetics and DNA Methylation

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Haemoglobinuria is associated with chronic kidney disease and its progression in patients with sickle cell anaemia

Saraf, S. L., Zhang, X., Kanias, T., Lash, J. P., Molokie, R. E., Oza, B., Lai, C., Rowe, J. H., Gowhari, M., Hassan, J., et al. (2014) · British Journal of Haematology

Hemoglobinopathies and Related DisordersChronic Kidney Disease and Diabetes

Cited by 120

Identification of human pathways acting on nuclear non-coding RNAs using the Mirror forward genetic approach

Che, R., Panah, M., Mirani, B., Knowles, K., Ostapovich, A., Majumdar, D., Chen, X., DeSimone, J., White, W., Noonan, M., et al. (2025) · Nature Communications

RNA Research and SplicingCancer-related molecular mechanisms research

Cited by 7