Fässler, Reinhard

Rapid leukocyte migration by integrin-independent flowing and squeezing

Lämmermann, T., Bader, B. L., Monkley, S. J., Worbs, T., Wedlich-Söldner, R., Hirsch, K., Keller, M., Förster, R., Critchley, D. R., Fässler, R., et al. (2008) · Nature

Cellular Mechanics and InteractionsCell Adhesion Molecules Research

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SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function

Krüger, M., Moser, M., Ussar, S., Thievessen, I., Luber, C. A., Forner, F., Schmidt, S., Zanivan, S., Fässler, R., & Mann, M. (2008) · Cell

Advanced Proteomics Techniques and ApplicationsErythrocyte Function and Pathophysiology

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Absence of integrin α7 causes a novel form of muscular dystrophy

Mayer, U., Saher, G., Fässler, R., Bornemann, A., Echtermeyer, F., Mark, H. V. D., Miosge, N., Pösch, E., & Mark, K. V. D. (1997) · Nature Genetics

Muscle Physiology and DisordersCell Adhesion Molecules Research

Cited by 451

Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin

Theodosiou, M., Widmaier, M., Böttcher, R. T., Rognoni, E., Veelders, M., Bharadwaj, M., Lambacher, A., Austen, K., Müller, D. J., Zent, R., et al. (2016) · eLife

Cell Adhesion Molecules ResearchCellular Mechanics and Interactions

Cited by 279

Brevican-Deficient Mice Display Impaired Hippocampal CA1 Long-Term Potentiation but Show No Obvious Deficits in Learning and Memory

Brakebusch, C., Seidenbecher, C. I., Asztely, F., Rauch, U., Matthies, H., Meyer, H., Krug, M., Böckers, T. M., Zhou, X., Kreutz, M. R., et al. (2002) · Molecular and Cellular Biology

Proteoglycans and glycosaminoglycans researchNeuroscience and Neuropharmacology Research

Cited by 264

Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon

Altrock, W. D., tom Dieck, S., Sokolov, M., Meyer, A. C., Sigler, A., Brakebusch, C., Fässler, R., Richter, K., Boeckers, T. M., Potschka, H., et al. (2003) · Neuron

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 258

Neurocan Is Dispensable for Brain Development

Zhou, X.-H., Brakebusch, C., Matthies, H., Oohashi, T., Hirsch, E., Moser, M., Krug, M., Seidenbecher, C. I., Boeckers, T. M., Rauch, U., et al. (2001) · Molecular and Cellular Biology

Proteoglycans and glycosaminoglycans researchNeurogenesis and neuroplasticity mechanisms

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Sorting nexin 17 prevents lysosomal degradation of β1 integrins by binding to the β1-integrin tail

Böttcher, R. T., Stremmel, C., Meves, A., Meyer, H., Widmaier, M., Tseng, H.-Y., & Fässler, R. (2012) · Nature Cell Biology

Cell Adhesion Molecules ResearchCellular transport and secretion

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Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis

Stenzel, D., Lundkvist, A., Sauvaget, D., Busse, M., Graupera, M., van der Flier, A., Wijelath, E. S., Murray, J., Sobel, M., Costell, M., et al. (2011) · Development

Angiogenesis and VEGF in CancerAxon Guidance and Neuronal Signaling

Cited by 154

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation

Rognoni, E., Widmaier, M., Jakobson, M., Ruppert, R., Ussar, S., Katsougkri, D., Böttcher, R. T., Lai-Cheong, J. E., Rifkin, D. B., McGrath, J. A., et al. (2014) · Nature Medicine

Skin and Cellular Biology ResearchCell Adhesion Molecules Research

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Bral1: its role in diffusion barrier formation and conduction velocity in the CNS

Bekku, Y., Vargová, L., Goto, Y., Vorísek, I., Dmytrenko, L., Narasaki, M., Ohtsuka, A., Fässler, R., Ninomiya, Y., Syková, E., et al. (2010) · The Journal of Neuroscience

Proteoglycans and glycosaminoglycans researchIon Transport and Channel Regulation

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Molecular cloning of Bral2, a novel brain-specific link protein, and immunohistochemical colocalization with brevican in perineuronal nets☆

Bekku, Y., Su, W.-D., Hirakawa, S., Fässler, R., Ohtsuka, A., Kang, J. S., Sanders, J., Murakami, T., Ninomiya, Y., & Oohashi, T. (2003) · Molecular and Cellular Neuroscience

Proteoglycans and glycosaminoglycans researchBone and Dental Protein Studies

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Glucocorticoid-regulated gene expression during cutaneous wound repair

BEER, H.-D., Fässler, R., & Werner, S. (2000) · Vitamins & Hormones

Wound Healing and TreatmentsDermatologic Treatments and Research

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Chondroitin Sulfate Perlecan Enhances Collagen Fibril Formation

Kvist, A. J., Johnson, A. E., Mörgelin, M., Gustafsson, E., Bengtsson, E., Lindblom, K., Aszódi, A., Fässler, R., Sasaki, T., Timpl, R., et al. (2006) · Journal of Biological Chemistry

Proteoglycans and glycosaminoglycans researchOsteoarthritis Treatment and Mechanisms

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Mammalian Skeletogenesis and Extracellular Matrix. What can We Learn from Knockout Mice?

Aszódi, A., F. Bateman, J., Gustafsson, E., Boot-Handford, R., & Fässler, R. (2000) · Cell Structure and Function

Connective tissue disorders researchOsteoarthritis Treatment and Mechanisms

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Knockdown and knockout of β1-integrin in hepatocytes impairs liver regeneration through inhibition of growth factor signalling

Speicher, T., Siegenthaler, B., Bogorad, R. L., Ruppert, R., Petzold, T., Padrissa-Altes, S., Bachofner, M., Anderson, D. G., Koteliansky, V., Fässler, R., et al. (2014) · Nature Communications

Liver physiology and pathologyCell Adhesion Molecules Research

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β1 Integrin-Mediated Adhesion Signalling Is Essential for Epidermal Progenitor Cell Expansion

Piwko-Czuchra, A., Koegel, H., Meyer, H., Bauer, M., Werner, S., Brakebusch, C., & Fässler, R. (2009) · PLoS ONE

Cell Adhesion Molecules ResearchSkin and Cellular Biology Research

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Integrin β1 regulates marginal zone B cell differentiation and PI3K signaling

Andreani, V., Ramamoorthy, S., Fässler, R., & Grosschedl, R. (2023) · Journal of Experimental Medicine

Cell Adhesion Molecules ResearchT-cell and B-cell Immunology

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