Pratt, William B.

Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones*

Pratt, W. B., & Toft, D. O. (1997) · Endocrine Reviews

Heat shock proteins researchEstrogen and related hormone effects

Cited by 1,791

HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

Kovacs, J. J., Murphy, P. J. M., Gaillard, S., Zhao, X., Wu, J.-T., Nicchitta, C. V., Yoshida, M., Toft, D. O., Pratt, W. B., & Yao, T.-P. (2005) · Molecular Cell

Heat shock proteins researchHistone Deacetylase Inhibitors Research

Cited by 1,153

Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement

Pratt, W. B., Galigniana, M. D., Harrell, J. M., & DeFranco, D. B. (2004) · Cellular Signalling

Heat shock proteins researchNuclear Structure and Function

Cited by 285

Evidence That the Peptidylprolyl Isomerase Domain of the hsp90-binding Immunophilin FKBP52 Is Involved in Both Dynein Interaction and Glucocorticoid Receptor Movement to the Nucleus

Galigniana, M. D., Radanyi, C., Renoir, J.-M., Housley, P. R., & Pratt, W. B. (2001) · Journal of Biological Chemistry

Signaling Pathways in DiseaseHeat shock proteins research

Cited by 236

Different regions of the immunophilin FKBP52 determine its association with the glucocorticoid receptor, hsp90, and cytoplasmic dynein

Silverstein, A. M., Galigniana, M. D., Kanelakis, K. C., Radanyi, C., Renoir, J.-M., & Pratt, W. B. (1999) · Journal of Biological Chemistry

Heat shock proteins researchSignaling Pathways in Disease

Cited by 186

Stepwise Assembly of a Glucocorticoid Receptor·hsp90 Heterocomplex Resolves Two Sequential ATP-dependent Events Involving First hsp70 and Then hsp90 in Opening of the Steroid Binding Pocket

Morishima, Y., Murphy, P. J. M., Li, D.-P., Sanchez, E. R., & Pratt, W. B. (2000) · Journal of Biological Chemistry

Heat shock proteins researchReceptor Mechanisms and Signaling

Cited by 166

Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus

Galigniana, M. D., Harrell, J. M., O'Hagen, H. M., Ljungman, M., & Pratt, W. B. (2004) · Journal of Biological Chemistry

Heat shock proteins researchCancer-related Molecular Pathways

Cited by 150

Geldanamycin, a Heat Shock Protein 90-Binding Benzoquinone Ansamycin, Inhibits Steroid-Dependent Translocation of the Glucocorticoid Receptor from the Cytoplasm to the Nucleus

Czar, M. J., Galigniana, M. D., Silverstein, A. M., & Pratt, W. B. (1997) · Biochemistry

Heat shock proteins researchEstrogen and related hormone effects

Cited by 141

Evidence for glucocorticoid receptor transport on microtubules by dynein

Harrell, J. M., Murphy, P. J. M., Morishima, Y., Chen, H., Mansfield, J. F., Galigniana, M. D., & Pratt, W. B. (2004) · Journal of Biological Chemistry

Heat shock proteins researchMicrotubule and mitosis dynamics

Cited by 129

Binding of hsp90-associated immunophilins to cytoplasmic dynein: direct binding and in vivo evidence that the peptidylprolyl isomerase domain is a dynein interaction domain

Galigniana, M. D., Harrell, J. M., Murphy, P. J. M., Chinkers, M., Radanyi, C., Renoir, J.-M., Zhang, M., & Pratt, W. B. (2002) · Biochemistry

Heat shock proteins researchSignaling Pathways in Disease

Cited by 117

The Hsp90 Cochaperone p23 Is the Limiting Component of the Multiprotein Hsp90/Hsp70-based Chaperone System in Vivo Where It Acts to Stabilize the Client Protein·Hsp90 Complex

Morishima, Y., Kanelakis, K. C., Murphy, P. J. M., Lowe, E. R., Jenkins, G. J., Osawa, Y., Sunahara, R. K., & Pratt, W. B. (2003) · Journal of Biological Chemistry

Heat shock proteins researchUbiquitin and proteasome pathways

Cited by 97

Retrograde transport of the glucocorticoid receptor in neurites requires dynamic assembly of complexes with the protein chaperone hsp90 and is linked to the CHIP component of the machinery for proteasomal degradation

Galigniana, M. D., Harrell, J. M., Housley, P. R., Patterson, C., Fisher, S. K., & Pratt, W. B. (2004) · Molecular Brain Research

Heat shock proteins researchCellular transport and secretion

Cited by 64