Lane, William S.

HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing

Ivan, M., Kondo, K., Yang, H., Kim, W., Valiando, J., Ohh, M., Salic, A., Asara, J. M., Lane, W. S., & Kaelin Jr., W. G. (2001) · Science

Cancer, Hypoxia, and MetabolismUbiquitin and proteasome pathways

Cited by 4,735

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

O'Reilly, M. S., Boehm, T., Shing, Y., Fukai, N., Vasios, G., Lane, W. S., Flynn, E., Birkhead, J. R., Olsen, B. R., & Folkman, J. (1997) · Cell

Angiogenesis and VEGF in CancerVascular Tumors and Angiosarcomas

Cited by 4,486

A mammalian protein targeted by G1-arresting rapamycin–receptor complex

Brown, E. J., Albers, M. W., Bum Shin, T., ichikawa, K., Keith, C. T., Lane, W. S., & Schreiber, S. L. (1994) · Nature

PI3K/AKT/mTOR signaling in cancerSignaling Pathways in Disease

Cited by 2,053

Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

Fenteany, G., Standaert, R. F., Lane, W. S., Choi, S., Corey, E. J., & Schreiber, S. L. (1995) · Science

Ubiquitin and proteasome pathwaysProtease and Inhibitor Mechanisms

Cited by 1,583

Acetylation of the p53 DNA-binding domain regulates apoptosis induction.

Sykes, S. M., Mellert, H. S., Holbert, M. A., Li, K., Marmorstein, R., Lane, W. S., & McMahon, S. B. (2006) · Molecular Cell

Cancer-related Molecular PathwaysUbiquitin and proteasome pathways

Cited by 752

BACH1, a Novel Helicase-like Protein, Interacts Directly with BRCA1 and Contributes to Its DNA Repair Function

Cantor, S. B., Bell, D. W., Ganesan, S., Kass, E. M., Drapkin, R., Grossman, S., Wahrer, D. C. R., Sgroi, D. C., Lane, W. S., Haber, D. A., et al. (2001) · Cell

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 674

Structural and Functional Conservation of the NuA4 Histone Acetyltransferase Complex from Yeast to Humans

Doyon, Y., Selleck, W., Lane, W. S., Tan, S., & Côté, J. (2004) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 597

A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness

Guenther, M. G., Lane, W. S., Fischle, W., Verdin, E., Lazar, M. A., & Shiekhattar, R. (2000) · Genes & Development

Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research

Cited by 489

Regulation of Histone Acetylation and Transcription by INHAT, a Human Cellular Complex Containing the Set Oncoprotein

Seo, S.-B., McNamara, P., Heo, S., Turner, A., Lane, W. S., & Chakravarti, D. (2001) · Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 481

AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain

Mîinea, C. P., Sano, H., Kane, S., Sano, E., Fukuda, M., Peränen, J., Lane, W. S., & Lienhard, G. E. (2005) · Biochemical Journal

Cellular transport and secretionMetabolism, Diabetes, and Cancer

Cited by 449

TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia

Mukhopadhyay, S., Wen, X., Chih, B., Nelson, C. D., Lane, W. S., Scales, S. J., & Jackson, P. K. (2010) · Genes & Development

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 435

ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage

Chen, L., Gilkes, D. M., Pan, Y., Lane, W. S., & Chen, J. (2005) · The EMBO Journal

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 260

Biomolecular Characterization and Protein Sequences of the Campanian Hadrosaur B. canadensis

Schweitzer, M. H., Zheng, W., Organ, C. L., Avci, R., Suo, Z., Freimark, L. M., Lebleu, V. S., Duncan, M. B., Vander Heiden, M. G., Neveu, J. M., et al. (2009) · Science

Paleontology and Evolutionary BiologyEvolution and Paleontology Studies

Cited by 238

WD40 Repeat Proteins Striatin and S/G2 Nuclear Autoantigen Are Members of a Novel Family of Calmodulin-binding Proteins That Associate with Protein Phosphatase 2A

Moreno, C. S., Park, S., Nelson, K., Ashby, D., Hubalek, F., Lane, W. S., & Pallas, D. C. (2000) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 194

A protein phosphatase methylesterase (PME-1) is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2A

Ogris, E., Du, X., Nelson, K. C., Mak, E. K., Yu, X. X., Lane, W. S., & Pallas, D. C. (1999) · Journal of Biological Chemistry

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 191

ATM activates p53 by regulating MDM2 oligomerization and E3 processivity

Cheng, Q., Chen, L., Li, Z., Lane, W. S., & Chen, J. (2009) · The EMBO Journal

Cancer-related Molecular PathwaysUbiquitin and proteasome pathways

Cited by 165

Insulin-stimulated Phosphorylation of the Rab GTPase-activating Protein TBC1D1 Regulates GLUT4 Translocation

Peck, G. R., Chavez, J. A., Roach, W. G., Budnik, B. A., Lane, W. S., Karlsson, H. K. R., Zierath, J. R., & Lienhard, G. E. (2009) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerCellular transport and secretion

Cited by 95

The structure–function relationships of a natural nanoscale photonic device in cuttlefish chromatophores

Deravi, L. F., Magyar, A. P., Sheehy, S. P., Bell, G. R. R., Mäthger, L. M., Senft, S. L., Wardill, T. J., Lane, W. S., Kuzirian, A. M., Hanlon, R. T., et al. (2014) · Journal of The Royal Society Interface

Photonic Crystals and ApplicationsCephalopods and Marine Biology

Cited by 91

Phosphorylation Site Mutations Affect Herpes Simplex Virus Type 1 ICP0 Function

Davido, D. J., von Zagorski, W. F., Lane, W. S., & Schaffer, P. A. (2005) · Journal of Virology

Herpesvirus Infections and TreatmentsCytomegalovirus and herpesvirus research

Cited by 49