Hurwitz, Jerard

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

Luo, Y., Hurwitz, J., & Massagué, J. (1995) · Nature

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 549

Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

Flores-Rozas, H., Kelman, Z., Dean, F. B., Pan, Z. Q., Harper, J. W., Elledge, S. J., O'Donnell, M., & Hurwitz, J. (1994) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 416

Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

Bermudez, V. P., Lindsey-Boltz, L. A., Cesare, A. J., Maniwa, Y., Griffith, J. D., Hurwitz, J., & Sancar, A. (2003) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 324

Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination.

Unk, I., Hajdú, I., Fátyol, K., Hurwitz, J., Yoon, J.-H., Prakash, L., Prakash, S., & Haracska, L. (2008) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 250

Inhibition of nucleotide excision repair by the cyclin-dependent kinase inhibitor p21

Pan, Z.-Q., Reardon, J. T., Li, L., Flores-Rozas, H., Legerski, R., Sancar, A., & Hurwitz, J. (1995) · Journal of Biological Chemistry

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 151

Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis

Ladner, J. E., Pan, M., Hurwitz, J., & Kelman, Z. (2011) · Proceedings of the National Academy of Sciences

Enzyme Structure and FunctionDNA Repair Mechanisms

Cited by 33