Igarashi, Kazuhiko

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

Itoh, K., Chiba, T., Takahashi, S., Ishii, T., Igarashi, K., Katoh, Y., Oyake, T., Hayashi, N., Satoh, K., Hatayama, I., et al. (1997) · Biochemical and Biophysical Research Communications

Genomics, phytochemicals, and oxidative stressGlutathione Transferases and Polymorphisms

Cited by 3,999

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Itoh, K., Wakabayashi, N., Katoh, Y., Ishii, T., Igarashi, K., Engel, J. D., & Yamamoto, M. (1999) · Genes & Development

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 3,634

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

Kobayashi, A., Kang, M.-I., Okawa, H., Ohtsuji, M., Zenke, Y., Chiba, T., Igarashi, K., & Yamamoto, M. (2004) · Molecular and Cellular Biology

Genomics, phytochemicals, and oxidative stressUbiquitin and proteasome pathways

Cited by 2,224

Impaired glucose tolerance is a risk factor for cardiovascular disease, but not impaired fasting glucose. The Funagata Diabetes Study.

Tominaga, M., Eguchi, H., Manaka, H., Igarashi, K., Kato, T., & Sekikawa, A. (1999) · Diabetes Care

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Management and Research

Cited by 1,165

Hemoprotein Bach1 regulates enhancer availability of heme oxygenase‐1 gene

Sun, J., Hoshino, H., Takaku, K., Nakajima, O., Muto, A., Suzuki, H., Tashiro, S., Takahashi, S., Shibahara, S., Alam, J., et al. (2002) · The EMBO Journal

Heme Oxygenase-1 and Carbon MonoxideGenomics, phytochemicals, and oxidative stress

Cited by 637

Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages

Haldar, M., Kohyama, M., So, A. Y.-L., KC, W., Wu, X., Briseño, C. G., Satpathy, A. T., Kretzer, N. M., Arase, H., Rajasekaran, N. S., et al. (2014) · Cell

Iron Metabolism and DisordersPhagocytosis and Immune Regulation

Cited by 431

Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network

Sun, J., Brand, M., Zenke, Y., Tashiro, S., Groudine, M., & Igarashi, K. (2004) · Proceedings of the National Academy of Sciences

Genomics, phytochemicals, and oxidative stressHeme Oxygenase-1 and Carbon Monoxide

Cited by 364

The superoxide‐producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cells

Kuroda, J., Nakagawa, K., Yamasaki, T., Nakamura, K., Takeya, R., Kuribayashi, F., Imajoh‐Ohmi, S., Igarashi, K., Shibata, Y., Sueishi, K., et al. (2005) · Genes to Cells

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 275

Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein

Katoh, Y., Ikura, T., Hoshikawa, Y., Tashiro, S., Ito, T., Ohta, M., Kera, Y., Noda, T., & Igarashi, K. (2011) · Molecular Cell

Heme Oxygenase-1 and Carbon MonoxideCancer-related gene regulation

Cited by 185

Bach2 maintains T cells in a naive state by suppressing effector memory-related genes

Tsukumo, S.-I., Unno, M., Muto, A., Takeuchi, A., Kometani, K., Kurosaki, T., Igarashi, K., & Saito, T. (2013) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 168

Bach1 Repression of Ferritin and Thioredoxin Reductase1 Is Heme-sensitive in Cells and in Vitro and Coordinates Expression with Heme Oxygenase1, β-Globin, and NADP(H) Quinone (Oxido) Reductase1

Hintze, K. J., Katoh, Y., Igarashi, K., & Theil, E. C. (2007) · Journal of Biological Chemistry

Heme Oxygenase-1 and Carbon MonoxideIron Metabolism and Disorders

Cited by 110