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Prevention of Acute Renal Failure in Traumatic Rhabdomyolysis
Abstract
Following the collapse of a building, seven subjects (aged 18 to 41 years) were released from under the rubble within one to 28 hours. All seven suffered from extensive crush injuries with evidence of severe rhabdomyolysis and were treated by the induction of an alkaline solute diuresis immediately on their extrication from the debris. The leakage of muscle constitutents was estimated by quantifying the net total body potassium losses, which averaged 395 mEq (SD, +/- 198) over the first 60 hours of therapy. In the past, injuries of similar severity have been associated with a high incidence of acute renal failure and a high mortality rate, yet none of our patients had azotemia or renal failure. We attribute this success to the unprecedented early institution of appropriate therapy.
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Cited by
VANHOLDER, R., SEVER, M. S. D. D., EREK, E., & LAMEIRE, N. (2000) · Journal of the American Society of Nephrology · doi:10.1681/asn.v1181553 · Cited by 657
Rhabdomyolysis and myohemoglobinuric acute renal failure
Zager, R. A. (1996) · Kidney International · doi:10.1038/ki.1996.48 · Cited by 615
Management of Crush-Related Injuries after Disasters
Sever, M. S., Vanholder, R., & Lameire, N. (2006) · New England Journal of Medicine · doi:10.1056/nejmra054329 · Cited by 386
Zimmerman, J. L., & Shen, M. C. (2013) · Chest · doi:10.1378/chest.12-2016 · Cited by 346
Bruso, J. R., Hoffman, M. D., Rogers, I. R., Lee, L., Towle, G., & Hew-Butler, T. (2010) · Wilderness & Environmental Medicine · doi:10.1016/j.wem.2010.06.012 · Cited by 82
Metadata
- Authors
- Ron, D.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association
- Published
- 1984-02-01
- Volume
- 144
- Issue
- 2
- Pages
- 277-277
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2064292305
- Cited by
- 352
- References
- 0
- FWCI
- 9.29
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ron, D. (1984). Prevention of Acute Renal Failure in Traumatic Rhabdomyolysis. Archives of Internal Medicine. https://doi.org/10.1001/archinte.144.2.277
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
