The DOI matches its OpenAlex record; 36 of the 36 references it cites were found in a registry or an index.
Magnesium metabolism. A review with special reference to the relationship between intracellular content and serum levels
Abstract
Magnesium (Mg++) is a ubiquitous element in nature, playing a role in photosynthesis and many metabolic functions in humans. All enzymatic reactions that involve adenosine triphosphate have an absolute requirement for Mg++. Levels of Mg++ are controlled by the kidneys and gastrointestinal tract and appear closely linked to calcium, potassium, and sodium metabolism. The clinical manifestations and causes of abnormal Mg++ status are protean. Testing for altered Mg++ homeostasis is problematic. Serum levels, which are those generally measured, reflect only a small part of the total body content of Mg++. The intracellular content can be low, despite normal serum levels in a person with clinical Mg++ deficiency. Future directions in research related to intracellular content of Mg++ are discussed. Treatment of altered Mg++ status depends on the clinical setting and may include the addition of a potassium/Mg++-sparing drug to an existing diuretic regimen. Guidelines for therapy are given.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals
(1990) · Annals of Internal Medicine · doi:10.7326/0003-4819-113-6-487_2 · Cited by 4,500
Recommended Dietary Allowances.
(1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-114-9-822_3 · Cited by 3,905
Skou, J. C. (1960) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(60)90746-0 · Cited by 799
Bowes & Church's food values of portions commonly used
Pennington, J. A. T., & Spungen, J. H. (1985) · Medical Entomology and Zoology · Cited by 467
EXPERIMENTAL HUMAN MAGNESIUM DEPLETION
SHILS, M. E. (1969) · Medicine · doi:10.1097/00005792-196901000-00003 · Cited by 387
The chemical composition of the human body.
Widdowson, E. M., McCance, R. A., & Spray, C. (1951) · PubMed · Cited by 369
Evidence for Parathyroid Failure in Magnesium Deficiency
Anast, C. S., Mohs, J. M., Kaplan, S. L., & Burns, T. W. (1972) · Science · doi:10.1126/science.177.4049.606 · Cited by 349
Parathyroid Hormone Secretion in Magnesium Deficiency*
RUDE, R. K., OLDHAM, S. B., SHARP, C. F., & SINGER, F. R. (1978) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-47-4-800 · Cited by 257
INTRAVENOUS MAGNESIUM IN ACUTE MYOCARDIAL INFARCTION
Sandvad Rasmussen, H., Norregard, P., Lindeneg, O., Mcnair, P., Backer, V., & Balslev, S. (1986) · The Lancet · doi:10.1016/s0140-6736(86)90773-7 · Cited by 247
Magnesium therapy for torsades de pointes
Tzivoni, D., Keren, A., Cohen, A. M., Loebel, H., Zahavi, I., Chenzbraun, A., & Stern, S. (1984) · The American Journal of Cardiology · doi:10.1016/0002-9149(84)90025-0 · Cited by 226
Cited by
Magnesium in Aging, Health and Diseases
Barbagallo, M., Veronese, N., & Dominguez, L. J. (2021) · Nutrients · doi:10.3390/nu13020463 · Cited by 359
An RNA Sensor for Intracellular Mg2+
Cromie, M. J., Shi, Y., Latifi, T., & Groisman, E. A. (2006) · Cell · doi:10.1016/j.cell.2006.01.043 · Cited by 323
Review of the Refeeding Syndrome
Kraft, M. D., Btaiche, I. F., & Sacks, G. S. (2005) · Nutrition in Clinical Practice · doi:10.1177/0115426505020006625 · Cited by 316
Hypertension, Diabetes Mellitus, and Insulin Resistance The Role of Intracellular Magnesium
Paolisso, G. (1997) · American Journal of Hypertension · doi:10.1016/s0895-7061(96)00342-1 · Cited by 300
Magnesium: The Forgotten Electrolyte—A Review on Hypomagnesemia
Ahmed, F., & Mohammed, A. (2019) · Medical Sciences · doi:10.3390/medsci7040056 · Cited by 186
Metadata
- Authors
- Reinhart, R. A.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 1988-11-01
- Volume
- 148
- Issue
- 11
- Pages
- 2415
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W1980579387
- Cited by
- 279
- References
- 36
- FWCI
- 6.96
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Magnesium metabolism. A review with special reference to the relationship between intracellular content and serum levels. https://app.cochat.ai/papers/10.1001/archinte.148.11.2415
- The paper
- Reinhart, R. A. (1988). Magnesium metabolism. A review with special reference to the relationship between intracellular content and serum levels. Archives of Internal Medicine. https://doi.org/10.1001/archinte.148.11.2415
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
