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Should Patients With Heart Disease Exercise in the Morning or Afternoon?
Abstract
OBJECTIVE: To compare the cardiovascular risk of exercise in the morning and afternoon in patients with established heart disease. DESIGN: Retrospective cohort study. PATIENTS: Patients with established heart disease referred for participation in a comprehensive cardiac rehabilitation program. INTERVENTION: Supervised, submaximal exercise (1 hour three times per week) performed either in the morning (7:30 AM) or the afternoon (3 PM). MAIN OUTCOME: Documented cardiac events that occurred while patients were exercising in the rehabilitation programs. RESULTS: There were five cardiac events in 168,111 patient-hours of exercise in the morning, with an incidence of 3.0 +/- 1.3 events per 100,000 patient-hours. There were two events during the 84,491 patient-hours of exercise in the afternoon, for an incidence of 2.4 +/- 1.5 events per 100,000 patient-hours (not significant). The risk ratio of cardiac events during exercise in the morning compared with the afternoon was 1.27 (95% confidence interval, 0.25 to 6.55). CONCLUSION: In patients with coronary artery disease, the incidence of cardiac events is low during regular, submaximal exercise whether performed in the morning or the afternoon.
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“Murray et al.33 found no significant increase in cardiac events in morning as compared with afternoon cardiac-rehabilitation classes, but the study had insufficient power to exclude a relative risk of 6 or less and many patients were taking beta-blockers, which might decrease a morning peak in onset.34-36”
From Triggering of Acute Myocardial Infarction by Heavy Physical Exertion -- Protection against Triggering by Regular Exertion (1993) · cites this paper as [33]
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Cited by
Mittleman, M. A., Maclure, M., Tofler, G. H., Sherwood, J. B., Goldberg, R. J., & Muller, J. E. (1993) · New England Journal of Medicine · doi:10.1056/nejm199312023292301 · Cited by 1,431
Metadata
- Authors
- Murray, P. M.
- Affiliations
- Atrium Health Wake Forest Baptist (US)
- Corresponding author
- Murray, Paul M.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 1993-04-12
- Volume
- 153
- Issue
- 7
- Pages
- 833
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2076657453
- Cited by
- 35
- References
- 0
- Citations by year
- 2023: 2 · 2022: 1 · 2021: 2 · 2018: 1 · 2016: 2 · 2012: 1
- FWCI
- 3.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Keywords
- exercise timing, cardiac rehabilitation, coronary artery disease, submaximal exercise, cardiovascular risk, cardiac patients
- MeSH terms
- Adult, Aged, Aged, 80 and over, Circadian Rhythm, Female, Humans, Male, Middle Aged, Retrospective Studies, Exercise, Incidence, Myocardial Ischemia
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