The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Changing Patient Characteristics and the Effect on Mortality in Endocarditis
Abstract
BACKGROUND: Limited data exist on recent demographic and microbiological changes in infective endocarditis (IE) and the impact of these changes on patient survival. METHODS: Data were collected from all patients with definite or possible IE at Duke University Medical Center, Durham, NC, from 1993 to 1999. Logistic regression analysis was used to identify demographic and microbiological changes that occurred in patients with IE over the study period. The impact of these changes on survival was evaluated using Cox proportional hazards modeling. RESULTS: Among the 329 study patients, rates of hemodialysis dependence, immunosuppression, and Staphylococcus aureus infection increased during the study period (P=.04, P=.008, and P<.001, respectively), while rates of infection due to viridans group streptococci decreased (P=.007). Hemodialysis was independently associated with S aureus infection (odds ratio, 3.1; 95% confidence interval, 1.6-5.9). Patients with S aureus IE had a higher 1-year mortality rate (43.9% vs 32.5%; P=.04) that persisted after adjustment for other illness severity characteristics (hazard ratio, 1.5; 95% confidence interval, 1.03-2.3). CONCLUSIONS: The demographic and microbiological characteristics of IE at our institution have changed over the past decade in ways that suggest a link between medical practice and IE characteristics. Staphylococcus aureus has emerged as a dominant cause of IE, and is an independent predictor of mortality. These findings identify clinical settings that may warrant closer surveillance and more aggressive measures in the identification and prevention of endocarditis.
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Cites
Evaluation of new clinical criteria for the diagnosis of infective endocarditis
Bayer, A. S., Ward, J. I., Ginzton, L. E., & Shapiro, S. M. (1994) · The American Journal of Medicine · doi:10.1016/0002-9343(94)90144-9 · Cited by 227
Fowler, Jr., Sanders, L. L., Kong, L. K., McClelland, R. S., Gottlieb, G. S., Li, J., Ryan, T., Sexton, D. J., Roussakis, G., Harrell, L. J., et al. (1999) · Clinical Infectious Diseases · doi:10.1086/515076 · Cited by 196
Self-citationInfective endocarditis in children: clinical analyses and evaluation of two diagnostic criteria
MARCÓ DEL PONT, J., DE CICCO, L. T., VARTALITIS, C., ITHURRALDE, M., GALLO, J. P., VARGAS, F., GIANANTONIO, C. A., & QUIRÓS, R. E. (1995) · The Pediatric Infectious Disease Journal · doi:10.1097/00006454-199512000-00010 · Cited by 106
Hoen, B., Selton-Suty, C., Danchin, N., Weber, M., Villemot, J.-P., Mathieu, P., Floquet, J., & Canton, P. (1995) · Clinical Infectious Diseases · doi:10.1093/clinids/21.4.905 · Cited by 104
Cited by
Otto, C. M., Nishimura, R. A., Bonow, R. O., Carabello, B. A., Erwin, J. P., Gentile, F., Jneid, H., Krieger, E. V., Mack, M., McLeod, C., et al. (2021) · Circulation · doi:10.1161/cir.0000000000000923 · Cited by 3,686
2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease
Nishimura, R. A., Otto, C. M., Bonow, R. O., Carabello, B. A., Erwin, J. P., Guyton, R. A., O’Gara, P. T., Ruiz, C. E., Skubas, N. J., Sorajja, P., et al. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2014.02.536 · Cited by 3,523
Otto, C. M., Nishimura, R. A., Bonow, R. O., Carabello, B. A., Erwin, J. P., Gentile, F., Jneid, H., Krieger, E. V., Mack, M., McLeod, C., et al. (2021) · Circulation · doi:10.1161/cir.0000000000000932 · Cited by 2,449
Murdoch, D. R. (2009) · Archives of Internal Medicine · doi:10.1001/archinternmed.2008.603 · Cited by 2,362
Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009)
Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and by the International Society of Chemotherapy (ISC) for Infection and Cancer, Habib, G., Hoen, B., Tornos, P., Thuny, F., Prendergast, B., Vilacosta, I., Moreillon, P., de Jesus Antunes, M., Thilen, U., et al. (2009) · European Heart Journal · doi:10.1093/eurheartj/ehp285 · Cited by 2,014
Metadata
- Authors
- Cabell, C. H., Jollis, J. G., Peterson, G. E., Corey, G. R., Anderson, D. J., Sexton, D. J., Woods, C. W., Reller, L. B., Ryan, T., & Fowler, V. G.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 2002-01-14
- Volume
- 162
- Issue
- 1
- Pages
- 90
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2081623389
- Cited by
- 548
- References
- 4
- FWCI
- 20.44
- Type
- journal article
- Language
- en
- Open access
- closed
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- Cabell, C. H., Jollis, J. G., Peterson, G. E., Corey, G. R., Anderson, D. J., Sexton, D. J., Woods, C. W., Reller, L. B., Ryan, T., & Fowler, V. G. (2002). Changing Patient Characteristics and the Effect on Mortality in Endocarditis. Archives of Internal Medicine. https://doi.org/10.1001/archinte.162.1.90
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