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Effects of Lifestyle on Hemostasis, Fibrinolysis, and Platelet Reactivity: A Systematic Review
Abstract
The pathophysiology of atherothrombosis in cardiovascular disease is complex and multifactorial. No doubt, lifestyle habits such as exercise, smoking, diet, and alcohol consumption may have significant influence on cardiovascular disease. As the hemostatic system is assuming an increasingly prominent role in the pathogenesis and progression of atherovascular diseases, this review evaluates the effects of lifestyle habits (or lifestyle modifications) on blood coagulation, fibrinolysis, and platelet reactivity.
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“Increasing physical activity maintains or adds to physical fitness, improves serum lipid levels, decreases blood pressure, increases insulin sensitivity and glucose tolerance, improves vascular endothelial function, and decreases thrombosis risk591–593).”
From Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017 (2018) · cites this paper as [591]
In the citing paper
“Increasing physical activity maintains or adds to physical fitness, improves serum lipid levels, decreases blood pressure, increases insulin sensitivity and glucose tolerance, improves vascular endothelial function, and decreases thrombosis risk591–593).”
From Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017 (2018) · cites this paper as [591]
In the citing paper
“Increasing physical activity maintains or adds to physical fitness, improves serum lipid levels, decreases blood pressure, increases insulin sensitivity and glucose tolerance, improves vascular endothelial function, and decreases thrombosis risk591–593).”
From Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017 (2018) · cites this paper as [591]
In the citing paper
“Increasing physical activity maintains or adds to physical fitness, improves serum lipid levels, decreases blood pressure, increases insulin sensitivity and glucose tolerance, improves vascular endothelial function, and decreases thrombosis risk591–593).”
From Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017 (2018) · cites this paper as [591]
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Metadata
- Authors
- Lee, K. W., & Lip, G. Y. H.
- Affiliations
- Birmingham City Hospital (GB)
- ORCID
- Lip, Gregory Y. H.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 2003-10-27
- Volume
- 163
- Issue
- 19
- Pages
- 2368
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2023679038
- Cited by
- 217
- References
- 287
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 2 · 2023: 3 · 2022: 9 · 2021: 7 · 2020: 4 · 2019: 5 · 2018: 6 · 2017: 2 · 2016: 10 · 2015: 8 · 2014: 7 · 2013: 18 · 2012: 11
- FWCI
- 6.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
- Topics
- Health Sciences › Medicine › Hematology › Blood Coagulation and Thrombosis Mechanisms
- Health Sciences › Medicine › Hematology › Blood properties and coagulation
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- lifestyle factors, hemostasis, fibrinolysis, platelet reactivity, atherothrombosis, cardiovascular disease, physical activity, smoking, diet, alcohol consumption, coagulation, lifestyle modification
- MeSH terms
- Blood Platelets, Body Weight, Cardiovascular Diseases, Fibrinolysis, Hemostasis, Humans, Life Style, Physical Endurance, Smoking, Stress, Psychological, Thrombosis, Health Behavior, Exercise, Comorbidity, Randomized Controlled Trials as Topic, Plasminogen Activator Inhibitor 1
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