The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Complementary and Alternative Therapies for the Management of Menopause-Related Symptoms: A Systematic Evidence Review
Abstract
BACKGROUND: Nearly half of adults in the United States use complementary and alternative therapies each year for a variety of reasons. These therapies are increasingly popular among women seeking alternatives to treatment with estrogen for managing menopausal symptoms. The objective of this review was to assess the effectiveness of complementary and alternative therapies in the management of menopausal symptoms. DATA SOURCES: MEDLINE, PsychINFO, Cochrane Library database, MANTIS, and AMED. STUDY SELECTION: Full-text, English-language, randomized controlled trials and meta-analyses comparing a complementary or alternative therapy with placebo or control for treatment of menopausal symptoms. DATA EXTRACTION: All eligible trials were reviewed, abstracted into evidence tables, and rated for quality. DATA SYNTHESIS: Seventy randomized controlled trials met inclusion criteria. Forty-eight studies of phytoestrogens and other biologically based agents showed mixed results. Smaller numbers of studies using mind-body, energy, manipulative, and body-based therapies and whole medical systems showed little benefit in treating menopausal symptoms. CONCLUSIONS: Although individual trials suggest benefits from certain therapies, data are insufficient to support the effectiveness of any complementary and alternative therapy in this review for the management of menopausal symptoms. Many of these potential therapies warrant further study in trials with rigorous scientific designs to determine benefit and safety.
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Van Patten, C. L., Olivotto, I. A., Chambers, G. K., Gelmon, K. A., Hislop, T. G., Templeton, E., Wattie, A., & Prior, J. C. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.2002.20.6.1449 · Cited by 265
Atkinson, C., Warren, R. M., Sala, E., Dowsett, M., Dunning, A. M., Healey, C. S., Runswick, S., Day, N. E., & Bingham, S. A. (2004) · Breast Cancer Research · doi:10.1186/bcr773 · Cited by 151
Cited by
Treatment of symptoms of the menopause: an Endocrine Society Clinical Practice Guideline
Stuenkel, C. A., Davis, S. R., Gompel, A., Lumsden, M. A., Murad, M. H., Pinkerton, J. V., & Santen, R. J. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-2236 · Cited by 884
Murphy, C. C., Bartholomew, L. K., Carpentier, M. Y., Bluethmann, S. M., & Vernon, S. W. (2012) · Breast Cancer Research and Treatment · doi:10.1007/s10549-012-2114-5 · Cited by 708
The potential health effects of dietary phytoestrogens
Rietjens, I. M. C. M., Louisse, J., & Beekmann, K. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13622 · Cited by 490
Female Sex and Alzheimer's Risk: The Menopause Connection
Scheyer, O., Rahman, A., Hristov, H., Berkowitz, C., Isaacson, R. S., Diaz Brinton, R., & Mosconi, L. (2018) · The Journal of Prevention of Alzheimer's Disease · doi:10.14283/jpad.2018.34 · Cited by 268
Efficacy of Escitalopram for Hot Flashes in Healthy Menopausal Women: A Randomized Controlled Trial
Freeman, E. W. (2011) · JAMA · doi:10.1001/jama.2010.2016 · Cited by 245
Metadata
- Authors
- Nedrow, A., Miller, J., Walker, M., Nygren, P., Huffman, L. H., & Nelson, H. D.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 2006-07-24
- Volume
- 166
- Issue
- 14
- Pages
- 1453
- ISSN
- 0003-9926
- OpenAlex
- W2114368286
- Cited by
- 242
- References
- 2
- FWCI
- 16.14
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Complementary and Alternative Therapies for the Management of Menopause-Related Symptoms: A Systematic Evidence Review. https://app.cochat.ai/papers/10.1001/archinte.166.14.1453
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- Nedrow, A., Miller, J., Walker, M., Nygren, P., Huffman, L. H., & Nelson, H. D. (2006). Complementary and Alternative Therapies for the Management of Menopause-Related Symptoms: A Systematic Evidence Review. Archives of Internal Medicine. https://doi.org/10.1001/archinte.166.14.1453
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
