The DOI matches its Crossref record.
Neurosyphilis
Abstract
Syphilis and its consequent central nervous system sequelae remain clinical problems, especially when presenting in the unfamiliar acute meningeal forms of syphilitic meningitis and meningovascular syphilis. The diagnosis of neurosyphilis of all types depends on evaluation of spinal fluid reactivity as evidenced by pleocytosis and increased protein content with reactive serology. The cerebrospinal fluid is always abnormal in active disease, and only active disease responds to treatment. Penicillin remains the drug of choice for all forms of neurosyphilis, but disease progression has been frequently reported following the use of penicillin G benzathine. Documentation of cerebrospinal fluid resolution over the months following penicillin therapy is required to confirm curative treatment.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Syphilis: Review with Emphasis on Clinical, Epidemiologic, and Some Biologic Features
Singh, A. E., & Romanowski, B. (1999) · Clinical Microbiology Reviews · doi:10.1128/cmr.12.2.187 · Cited by 638
LaFond, R. E., & Lukehart, S. A. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.19.1.29-49.2006 · Cited by 634
Hook, E. W., & Marra, C. M. (1992) · New England Journal of Medicine · doi:10.1056/nejm199204163261606 · Cited by 470
Neurosyphilis in the modern era
Timmermans, M. (2004) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2004.031922 · Cited by 257
Metadata
- Authors
- Simon, R. P.
- Venue
- Archives of Neurology
- Publisher
- American Medical Association (AMA)
- Published
- 1985-06-01
- Volume
- 42
- Issue
- 6
- Pages
- 606-613
- ISSN
- 0003-9942 (ISSN-L)
- OpenAlex
- W4233624182
- Cited by
- 180
- References
- 0
- FWCI
- 8.61
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Neurosyphilis. https://app.cochat.ai/papers/10.1001/archneur.1985.04060060112021
- The paper
- Simon, R. P. (1985). Neurosyphilis. Archives of Neurology. https://doi.org/10.1001/archneur.1985.04060060112021
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
