The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
White-Matter Hyperintensity and Neuropsychological Functions in Dementia and Healthy Aging
Abstract
The relationship between quantitative measurements of brain white-matter hyperintensity (WMH), assessed by magnetic resonance imaging and neuropsychological functions, was explored in demented patients and healthy aged individuals with and without WMH in 12 brain regions. The prevalence of WMH was significantly higher in vascular dementia compared with Alzheimer's disease, especially in posterior periventricular regions. Results showed no difference in any neuropsychological measurement between healthy aged adults with and without WMH. The demented patients with WMH were more impaired in tests of visuoconstruction, attention, finger-motor speed, and latency of tactile identification of objects compared with patients without WMH. These impairments were related mainly to posterior periventricular WMH. There was no relationship between WMH and global cognitive functioning in the demented patients. The degree of WMH was related to age and blood pressure. The data suggest that specific regional WMH may result in specific neuropsychological impairments.
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Awad, I. A., Johnson, P. C., Spetzler, R. F., & Hodak, J. A. (1986) · Stroke · doi:10.1161/01.str.17.6.1090 · Cited by 572
(1989) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/jnp.1.2.135 · Cited by 245
Cited by
de Leeuw, F.-E. (2001) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.70.1.9 · Cited by 1,291
Schmahmann, J. D., & Pandya, D. N. (2006) · doi:10.1093/acprof:oso/9780195104233.001.0001 · Cited by 1,157
The cognitive correlates of white matter abnormalities in normal aging: A quantitative review.
Gunning-Dixon, F. M., & Raz, N. (2000) · Neuropsychology · doi:10.1037/0894-4105.14.2.224 · Cited by 794
The Nature and Determinants of Neuropsychological Functioning in Late-LifeDepression
Butters, M. A., Whyte, E. M., Nebes, R. D., Begley, A. E., Dew, M. A., Mulsant, B. H., Zmuda, M. D., Bhalla, R., Meltzer, C. C., Pollock, B. G., et al. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.6.587 · Cited by 622
Cerebral White Matter Is Highly Vulnerable to Ischemia
Pantoni, L., Garcia, J. H., & Gutierrez, J. A. (1996) · Stroke · doi:10.1161/01.str.27.9.1641 · Cited by 608
Metadata
- Authors
- Almkvist, O., Wahlund, L.-O., Andersson-Lundman, G., Basun, H., & Backman, L.
- Venue
- Archives of Neurology
- Publisher
- American Medical Association (AMA)
- Published
- 1992-06-01
- Volume
- 49
- Issue
- 6
- Pages
- 626-632
- ISSN
- 0003-9942 (ISSN-L)
- OpenAlex
- W2075118788
- Cited by
- 195
- References
- 2
- FWCI
- 7.51
- Type
- journal article
- Language
- en
- Open access
- closed
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- Almkvist, O., Wahlund, L.-O., Andersson-Lundman, G., Basun, H., & Backman, L. (1992). White-Matter Hyperintensity and Neuropsychological Functions in Dementia and Healthy Aging. Archives of Neurology. https://doi.org/10.1001/archneur.1992.00530300062011
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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