BRAIN OF PATIENT A. AFTER BILATERAL FRONTAL LOBECTOMY; STATUS OF FRONTAL-LOBE PROBLEM
Abstract
PATIENT Joe A., on whom Dr. Walter Dandy performed a bilateral frontal lobectomy in 1930, died Aug. 31, 1949. Clinical descriptions have previously been recorded.1The necropsy is reported in this paper. A. was the first human being to undergo bilateral frontal lobectomy. Studies of A. were reported at the International Congress of Neurology in London in 1935. Egas Moniz was present at this meeting, where he described some of his early work on cerebal angiography. In the thinking which led him to initiate lobotomy, Moniz was much influenced by the London report of A.'s postoperative behavior and by Fulton and Jacobsen's description of chimpanzee behavior after a similar operation, described at the same meeting.2 Study of A. also has added to our understanding of frontal-lobe function. The role oflossof frontal tissue in symptom production has recently been minimized; some workers believe that the presence of
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This conclusion is largely consistent with previous reports that patients with even major lesions in the PFC show no apparent degradation in consciousness.
“This conclusion is largely consistent with previous reports that patients with even major lesions in the PFC show no apparent degradation in consciousness (Hebb and Penfield, 1940;Mettler, 1949;Brickner, 1952;Pollen, 1999).”
From Does the Prefrontal Cortex Play an Essential Role in Consciousness? Insights from Intracranial Electrical Stimulation of the Human Brain (2021) · cites this paper as Brickner, 1952
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References 27 · Cited by 31
- Authors
- BRICKNER, R. M.
- Corresponding author
- BRICKNER, RICHARD M.
- Venue
- Archives of Neurology And Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1952-09-01
- Volume
- 68
- Issue
- 3
- Pages
- 293
- ISSN
- 0096-6754 (ISSN-L)
- OpenAlex
- W2057756799
- Cited by
- 31
- References
- 27
- Citations by year
- 2026: 1 · 2025: 3 · 2023: 3 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 1 · 2018: 1 · 2017: 4 · 2016: 1 · 2015: 1 · 2014: 2
- FWCI
- 2.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Neurology And Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Neurology and Historical Studies
- Social Sciences › Psychology › Clinical Psychology › Historical Psychiatry and Medical Practices
- Health Sciences › Medicine › Neurology › History of Medical Practice
- Keywords
- frontal lobe function, lobotomy, Walter Dandy, postoperative behavior, frontal lobe lesions, frontal lobe epilepsy
- MeSH terms
- Brain, Frontal Lobe, Humans, Psychosurgery
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