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Histopathology of Juvenile Retinoschisis
Abstract
Our clinicopathologic data in a familial case of juvenile retinoschisis are presented. The schisis is seen histologically as a splitting of the sensory retina, predominantly within the nerve fiber layer. This site of splitting differs from that observed in the typical case of senile retinoschisis, in which the splitting occurs in the middle layers of the sensory retina. The histologic appearance observed in juvenile retinoschisis, however, is quite similar to that found in nonfamilial cases of retinoschisis in infants. A brother of the patient also had bilateral juvenile retinoschisis. The patient's other six siblings (all male) and both parents are free of the disorder. To our knowledge, this is the first histopathologic report of familial juvenile retinoschisis in a well-documented case.
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Citations
Cited by
Positional cloning of the gene associated with X-linked juvenile retinoschisis
Sauer, C. G., Gehrig, A., Warneke-Wittstock, R., Marquardt, A., Ewing, C. C., Gibson, A., Lorenz, B., Jurklies, B., & Weber, B. H. F. (1997) · Nature Genetics · doi:10.1038/ng1097-164 · Cited by 497
Gass, J. D. M. (1999) · Archives of Ophthalmology · doi:10.1001/archopht.117.6.821 · Cited by 342
Clinical Features in Affected Males With X-Linked Retinoschisis
George, N. D. L. (1996) · Archives of Ophthalmology · doi:10.1001/archopht.1996.01100130270007 · Cited by 255
Metadata
- Authors
- Yanoff, M., Rahn, E. K., & Zimmerman, L. E.
- Venue
- Archives of Ophthalmology
- Publisher
- American Medical Association (AMA)
- Published
- 1968-01-01
- Volume
- 79
- Issue
- 1
- Pages
- 49-53
- ISSN
- 0003-9950 (ISSN-L)
- OpenAlex
- W2053246781
- Cited by
- 195
- References
- 0
- FWCI
- 1.74
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Histopathology of Juvenile Retinoschisis. https://app.cochat.ai/papers/10.1001/archopht.1968.03850040051014
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- Yanoff, M., Rahn, E. K., & Zimmerman, L. E. (1968). Histopathology of Juvenile Retinoschisis. Archives of Ophthalmology. https://doi.org/10.1001/archopht.1968.03850040051014
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