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Interferon-Associated Retinopathy
Abstract
Interferon alfa is used to treat various systemic disorders and recently has been suggested as a possible treatment for choroidal neovascularization. We report 10 cases of retinal ischemia associated with the use of interferon alfa for various illnesses. The retinal findings include cotton-wool spot formation, capillary nonperfusion, arteriolar occlusion, and hemorrhage. The retinal complications may sometimes be reversible when treatment is stopped. Our findings emphasize the need to have patients who are receiving interferon alfa therapy monitored for these retinal complications, which may rarely be associated with permanent loss of vision secondary to closure of retinal capillaries.
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Citations
Cited by
Side effects of α interferon in chronic hepatitis C
Dusheiko, G. (1997) · Hepatology · doi:10.1002/hep.510260720 · Cited by 397
Clinical Toxicity of the Interferons
Vial, T., & Descotes, J. (1994) · Drug Safety · doi:10.2165/00002018-199410020-00003 · Cited by 269
Occult Choroidal Neovascularization in Age-Related Macular Degeneration: A Natural History Study
Stevens, T. S. (1997) · Archives of Ophthalmology · doi:10.1001/archopht.1997.01100150347006 · Cited by 110
Metadata
- Authors
- Guyer, D. R.
- Venue
- Archives of Ophthalmology
- Publisher
- American Medical Association (AMA)
- Published
- 1993-03-01
- Volume
- 111
- Issue
- 3
- Pages
- 350
- ISSN
- 0003-9950 (ISSN-L)
- OpenAlex
- W2141779237
- Cited by
- 282
- References
- 0
- FWCI
- 21.45
- Type
- journal article
- Language
- en
- Open access
- closed
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- Guyer, D. R. (1993). Interferon-Associated Retinopathy. Archives of Ophthalmology. https://doi.org/10.1001/archopht.1993.01090030068041
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
