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The Lens Opacities Classification System III
Abstract
OBJECTIVE: To develop the Lens Opacities Classification System III (LOCS III) to overcome the limitations inherent in lens classification using LOCS II. These limitations include unequal intervals between standards, only one standard for color grading, use of integer grading, and wide 95% tolerance limits. DESIGN AND RESULTS: The LOCS III contains an expanded set of standards that were selected from the Longitudinal Study of Cataract slide library at the Center for Clinical Cataract Research, Boston, Mass. It consists of six slit-lamp images for grading nuclear color (NC) and nuclear opalescence (NO), five retroillumination images for grading cortical cataract (C), and five retroillumination images for grading posterior subcapsular (P) cataract. Cataract severity is graded on a decimal scale, and the standards have regularly spaced intervals on a decimal scale. The 95% tolerance limits are reduced from 2.0 for each class with LOCS II to 0.7 for nuclear opalescence, 0.7 for nuclear color, 0.5 for cortical cataract, and 1.0 for posterior subcapsular cataract with the LOCS III, with excellent interobserver agreement. CONCLUSION: The LOCS III is an improved LOCS system for grading slit-lamp and retroillumination images of age-related cataract.
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Cited by
Stewart, F. A., Akleyev, A. V., Hauer-Jensen, M., Hendry, J. H., Kleiman, N. J., MacVittie, T. J., Aleman, B. M., Edgar, A. B., Mabuchi, K., Muirhead, C. R., et al. (2012) · Annals of the ICRP · doi:10.1016/j.icrp.2012.02.001 · Cited by 1,604
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Syddall, H., Cooper, C., Martin, F., Briggs, R., & Aihie Sayer, A. (2003) · Age and Ageing · doi:10.1093/ageing/afg111 · Cited by 564
Foong, A. W. P., Saw, S.-M., Loo, J.-L., Shen, S., Loon, S.-C., Rosman, M., Aung, T., Tan, D. T. H., Tai, E. S., & Wong, T. Y. (2007) · Ophthalmic Epidemiology · doi:10.1080/09286580600878844 · Cited by 432
Hsu, W.-M., Cheng, C.-Y., Liu, J.-H., Tsai, S.-Y., & Chou, P. (2004) · Ophthalmology · doi:10.1016/j.ophtha.2003.05.011 · Cited by 355
Ghazi, N. G., Abboud, E. B., Nowilaty, S. R., Alkuraya, H., Alhommadi, A., Cai, H., Hou, R., Deng, W.-T., Boye, S. L., Almaghamsi, A., et al. (2016) · Human Genetics · doi:10.1007/s00439-016-1637-y · Cited by 243
Metadata
- Authors
- Chylack, L. T.
- Venue
- Archives of Ophthalmology
- Publisher
- American Medical Association (AMA)
- Published
- 1993-06-01
- Volume
- 111
- Issue
- 6
- Pages
- 831
- ISSN
- 0003-9950 (ISSN-L)
- OpenAlex
- W2099838434
- Cited by
- 2,913
- References
- 0
- FWCI
- 13.95
- Type
- journal article
- Language
- en
- Open access
- closed
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