Burden of Anxiety Disorders in Pediatric Medical Settings: Prevalence, Phenomenology, and a Research Agenda
Open accessAbstract
The current review describes the phenomenology of several common anxiety disorders in children and adolescents as they present in medical settings. Anxiety disorders and associated features in children are described, along with epidemiology, functional impairment, common somatic complaints, medical comorbidity, health care utilization, and presentation in general and in specialty pediatric medical settings. Recommendations for clinical management in pediatric settings are presented, and evidence-based interventions and emerging treatments for pediatric anxiety disorders are described. The review concludes with a discussion of future research directions that may lead to increased recognition and improved management of anxiety disorders in pediatric medical settings.
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Chronic medical conditions substantially increase the risk of experiencing anxiety symptoms in children, with an estimated 20% to 50% of those with asthma, type 1 diabetes, epilepsy, inflammatory bowel disease, juvenile idiopathic arthritis, congenital heart disease, and sickle cell disease developing an anxiety disorder.
“Chronic medical conditions substantially increase the risk of experiencing anxiety symptoms in children, with an estimated 20% to 50% of those with asthma, type 1 diabetes, epilepsy, inflammatory bowel disease, juvenile idiopathic arthritis, congenital heart disease, and sickle cell disease developing an anxiety disorder [11,16].”
From Psychological and Psychiatric Comorbidities in Youth with Serious Physical Illness (2022) · cites this paper as [11]
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Experimental — accuracy not yet measuredThe relationship between psychiatric and other medical conditions is bidirectional, with this comorbidity being associated with greater functional impairment than would be expected with either alone.
“The relationship between psychiatric and other medical conditions is bidirectional, with this comorbidity being associated with greater functional impairment than would be expected with either alone [11].”
From Psychological and Psychiatric Comorbidities in Youth with Serious Physical Illness (2022) · cites this paper as [11]
The ‘Anxiety Disorders and Medical Comorbidity’ section (page not supplied) says the relationship between anxiety disorders and medical conditions is likely bidirectional. The passage labeled ‘Specific phobia’ (page not supplied) says their comorbidity appears to produce greater impairment in children than either disorder alone. The claim extends these points from pediatric anxiety disorders to psychiatric conditions generally, which this source does not establish. (LLM, conf=0.86)
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References 78 · Cited by 110
Research works printed but not linked: 1
- [49]49. Bernal P, Estroff DB, Aboudarham JF, Murphy M, Keller A, Jellinek MS. Psycho- social morbidity: the economic burden in a pediatric health maintenance orga- nization sample. Arch Pediatr Adolesc Med. 2000;154(3):261-266.
- Authors
- Ramsawh, H. J., Chavira, D. A., & Stein, M. B.
- Affiliations
- University of California San Diego (US)
- F. Hoffmann-La Roche AG (CH)
- Venue
- Archives of Pediatrics & Adolescent Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 2010-10-01
- Volume
- 164
- Issue
- 10
- Pages
- 965-72
- ISSN
- 1072-4710 (ISSN-L)
- PMC
- PMC3106429
- OpenAlex
- W2110951068
- Semantic Scholar
- 518534a2809e7aa776b42950ab7e12570d6e23e8
- Cited by
- 110
- References
- 78
- Citations by year
- 2026: 10 · 2025: 10 · 2024: 6 · 2023: 11 · 2022: 11 · 2021: 7 · 2020: 10 · 2019: 7 · 2018: 6 · 2017: 4 · 2016: 7 · 2015: 5 · 2014: 3 · 2013: 5 · 2012: 6
- FWCI
- 0.61
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Archives of Pediatrics and Adolescent Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Eli Lilly and Company
- GlaxoSmithKline
- University of California, San Diego (T32 MH018399)
- National Institute of Mental Health (K24MH064122, K01MH072952, R34MH090149, MH018399, T32MH018399)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- childhood anxiety disorders, children and adolescents, healthcare settings, somatic symptoms, functional disability, comorbidities, health care utilization, clinical management, evidence-based interventions, emerging treatments
- MeSH terms
- Adolescent, Adolescent Psychiatry, Anxiety Disorders, Child, Child Psychiatry, Emergency Service, Hospital, Humans, Pediatrics, Primary Health Care, United States, Comorbidity, Prevalence, Evidence-Based Medicine, Biomedical Research
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