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Drug and Sociotherapy in the Aftercare of Schizophrenic Patients: One-Year Relapse Rates
Abstract
The posthospital treatment of 374 schizophrenics was controlled and evaluated for two years. Relapse rates for the first year were recorded. At clinic intake, patients were randomly assigned to major role therapy (MRT; social casework and vocational rehabilitation counseling) and stabilized through the administration of chlorpromazine. After two months, further assignment to drug or placebo was made. Four groups were studied in each of three aftercare clinics: placebo alone; placebo and MRT; drug alone; drug and MRT. Relapse in the placebo group is twice that of the drug group, but one half of all relapsers (drug and placebo) cease medication prior to relapse. The prophylactic action of the drug is established for many remitted schizophrenics. The MRT also lowers relapse rate significantly, but only after six months. Drug and sociotherapy effects are additive rather interactive by 12 months. Results replicate across all clinics.
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Cited by
Leucht, S., Tardy, M., Komossa, K., Heres, S., Kissling, W., Salanti, G., & Davis, J. M. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60239-6 · Cited by 931
A Controlled Trial of Social Intervention in the Families of Schizophrenic Patients
Leff, J., Kuipers, L., Berkowitz, R., Eberlein-Vries, R., & Sturgeon, D. (1982) · British Journal of Psychiatry · doi:10.1192/bjp.141.2.121 · Cited by 869
Placebo interventions for all clinical conditions
Hróbjartsson, A., & Gøtzsche, P. C. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003974.pub3 · Cited by 777
Compliance With Medication Regimens for Mental and Physical Disorders
Cramer, J. A., & Rosenheck, R. (1998) · Psychiatric Services · doi:10.1176/ps.49.2.196 · Cited by 725
Thompson, A., Winsper, C., Marwaha, S., Haynes, J., Alvarez-Jimenez, M., Hetrick, S., Realpe, A., Vail, L., Dawson, S., & Sullivan, S. A. (2018) · BJPsych Open · doi:10.1192/bjo.2018.17 · Cited by 44
Metadata
- Authors
- Hogarty, G. E.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1973-01-01
- Volume
- 28
- Issue
- 1
- Pages
- 54
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W4231972751
- Cited by
- 282
- References
- 0
- FWCI
- 14.94
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hogarty, G. E. (1973). Drug and Sociotherapy in the Aftercare of Schizophrenic Patients: One-Year Relapse Rates. Archives of General Psychiatry. https://doi.org/10.1001/archpsyc.1973.01750310038007
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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