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Treatment of Agoraphobia With Group Exposure In Vivo and Imipramine
Abstract
Seventy-six white agoraphobic women, 21 to 45 years old, were treated with combined group exposure in vivo and imipramine or placebo in a randomized double-blind study. A majority of the patients in both the placebo and imipramine groups showed moderate to marked improvement. However, imipramine therapy was significantly superior to placebo therapy on three of the four reported measures of improvement: primary phobia, spontaneous panic, and global improvement. There was a negative correlation between depression and outcome; ie, the more depressed patients fared worse on several outcome measures than those who were less depressed. A comparison of these patients with agoraphobic women previously treated with imipramine and imaginal desensitization showed a superiority of exposure in vivo midway in treatment, but no significant difference between the two groups at the completion of therapy.
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Citations
Cited by
Emotional processing of fear: Exposure to corrective information.
Foa, E. B., & Kozak, M. J. (1986) · Psychological Bulletin · doi:10.1037/0033-2909.99.1.20 · Cited by 5,396
Clark, D. M. (1986) · Behaviour Research and Therapy · doi:10.1016/0005-7967(86)90011-2 · Cited by 2,422
Barlow, D. H., Gorman, J. M., Shear, M. K., & Woods, S. W. (2000) · JAMA · doi:10.1001/jama.283.19.2529 · Cited by 953
Bandelow, B., Zohar, J., Hollander, E., Kasper, S., Möller, H.-J., WFSBP TASK FORCE ON TREATMENT GUIDE, Bandelow, B., Zohar, J., Hollander, E., Kasper, S., et al. (2008) · The World Journal of Biological Psychiatry · doi:10.1080/15622970802465807 · Cited by 854
Behavioral treatment of panic disorder
Barlow, D. H., Craske, M. G., Cerny, J. A., & Klosko, J. S. (1989) · Behavior Therapy · doi:10.1016/s0005-7894(89)80073-5 · Cited by 627
Metadata
- Authors
- Zitrin, C. M.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1980-01-01
- Volume
- 37
- Issue
- 1
- Pages
- 63
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W2103990085
- Cited by
- 332
- References
- 0
- FWCI
- 30.61
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zitrin, C. M. (1980). Treatment of Agoraphobia With Group Exposure In Vivo and Imipramine. Archives of General Psychiatry. https://doi.org/10.1001/archpsyc.1980.01780140065007
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
