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Schizotaxia Revisited
Abstract
A conjectured neural integrative defect (schizotaxia), due to a dominant schizogene completely penetrant for a parametric aberration in synaptic signal selectivity (hypokrisia), gives rise under ordinary social learning regimens to schizotypy, a personality showing ambivalence, aversive drift, dereism, autism, and cognitive slippage. Given unfavorable polygenic potentiators (eg, introversion, hypohedonia, and anxiety) and adverse life experiences (eg, childhood trauma or adult misfortune), around 10% develop schizophrenia. That schizophrenia is basically a neurologic disorder does not contradict whatever is known about its psychodynamics, nor preclude efficacy for psychotherapy or other psychosocial interventions. Research should concentrate on soft neurology and psychophysiology as indicators, being closer in the causal chain to the schizogene than psychometric, social, or high-level cognitive processes. Taxometric statistics are appropriate to testing a major locus model not simplistically formulated.
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Cited by
Types of dissociation and dissociative types: A taxometric analysis of dissociative experiences.
Waller, N., Putnam, F. W., & Carlson, E. B. (1996) · Psychological Methods · doi:10.1037/1082-989x.1.3.300 · Cited by 894
Monitoring and Care of Young People at Incipient Risk of Psychosis
Yung, A. R., McGorry, P. D., McFarlane, C. A., Jackson, H. J., Patton, G. C., & Rakkar, A. (1996) · Schizophrenia Bulletin · doi:10.1093/schbul/22.2.283 · Cited by 772
Meehl, P. E. (1990) · Psychological Inquiry · doi:10.1207/s15327965pli0102_1 · Cited by 673
Self-citationCognitive-perceptual, interpersonal, and disorganized features of schizotypal personality
Raine, A., Reynolds, C., Lencz, T., Scerbo, A., Triphon, N., & Kim, D. (1994) · Schizophrenia Bulletin · doi:10.1093/schbul/20.1.191 · Cited by 595
Can neuroscience be integrated into the DSM-V?
Hyman, S. E. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2218 · Cited by 516
Metadata
- Authors
- Meehl, P. E.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1989-10-01
- Volume
- 46
- Issue
- 10
- Pages
- 935
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W4230540421
- Cited by
- 349
- References
- 0
- FWCI
- 10.56
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
