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Cited by 1,487

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Naltrexone and Coping Skills Therapy for Alcohol Dependence: A Controlled Study

O'Malley, Stephanie S.·1992·Archives of General Psychiatry

Abstract

Ninety-seven alcohol-dependent patients were treated for 12 weeks in a double-blind, placebo-controlled study evaluating naltrexone and two manual guided psychotherapies in the treatment of alcohol dependence. Patients were randomized to receive either naltrexone or placebo and either coping skills/relapse prevention therapy or a supportive therapy designed to support the patient's own efforts at abstinence without teaching specific coping skills. Naltrexone proved superior to placebo in measures of drinking and alcohol-related problems, including abstention rates, number of drinking days, relapse, and severity of alcohol-related problems. Medication interacted with the type of psychotherapy received. The cumulative rate of abstinence was highest for patients treated with naltrexone and supportive therapy. For those patients who initiated drinking, however, patients who received naltrexone and coping skills therapy were the least likely to relapse.

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Crossref · 10.1001/archpsyc.1992.01820110045007

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Metadata

Authors
O'Malley, S. S.
Venue
Archives of General Psychiatry
Published
1992-11-01
Volume
49
Issue
11
Pages
881
ISSN
0003-990X (ISSN-L)
OpenAlex
W2093559862
Cited by
1,487
References
2
FWCI
31.22
Type
journal article
Language
en
Open access
closed

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