The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Causal Inferences Regarding Prenatal Alcohol Exposure and Childhood Externalizing Problems
Abstract
Context Existing research on the neurobehavioral consequences of prenatal alcohol exposure (PAE) has not adequately accounted for genetic and environmental confounds. Objective To examine the association between PAE and offspring externalizing problems in a large representative sample of families in the United States using measured covariates and a quasi-experimental design to account for unmeasured genetic and environmental confounds. Design This study combines information from the National Longitudinal Survey of Youth and the Children of the National Longitudinal Survey of Youth. The analyses statistically controlled for measured characteristics of the mothers and families and exposure to other prenatal psychoactive substances. In the primary analyses, siblings differentially exposed to prenatal alcohol were compared. Setting and participants Women were recruited from the community using a stratified and clustered probability sample and were followed longitudinally. The sample included 8621 offspring of 4912 mothers. Main outcome measures Maternal report of conduct problems (CPs) and attention/impulsivity problems (AIPs) during childhood (ages 4-11 years) using standardized assessments related to psychiatric diagnoses. Results There was an association between PAE and offspring CPs that was independent of confounded genetic and fixed environmental effects and the measured covariates. The CPs in children of mothers who drank daily during pregnancy were 0.35 SD greater than th…
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“Reduced maternal thyroid capacity, poor maternal wellness, maternal age, post-maturity of the foetus, long working hours, maternal stress, foetal stress, prenatal exposure to alcohol and tobacco, and antepartum haemorrhage are prenatal factors that could influence ADHD development [54, 58, 65].”
From Molecular Characterisation of the Mechanism of Action of Stimulant Drugs Lisdexamfetamine and Methylphenidate on ADHD Neurobiology: A Review (2022) · cites this paper as [65]
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Fetal Alcohol Spectrum Disorders: Neuropsychological and Behavioral Features
Mattson, S. N., Crocker, N., & Nguyen, T. T. (2011) · Neuropsychology Review · doi:10.1007/s11065-011-9167-9 · Cited by 674
Harold, G. T., & Sellers, R. (2018) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12893 · Cited by 383
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Ethanol and Cognition: Indirect Effects, Neurotoxicity and Neuroprotection: A Review
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Metadata
- Authors
- D’Onofrio, B. M., Van Hulle, C. A., Waldman, I. D., Rodgers, J. L., Rathouz, P. J., & Lahey, B. B.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 2007-11-01
- Volume
- 64
- Issue
- 11
- Pages
- 1296
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W2148565287
- Cited by
- 170
- References
- 55
- Citations by year
- 2026: 4 · 2025: 1 · 2024: 5 · 2023: 6 · 2022: 9 · 2021: 9 · 2020: 7 · 2019: 7 · 2018: 9 · 2017: 12 · 2016: 7 · 2015: 8 · 2014: 8 · 2013: 14 · 2012: 10
- FWCI
- 13.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of General Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (R01MH070025)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Keywords
- prenatal alcohol exposure, fetal alcohol spectrum disorders, child conduct problems, sibling comparison, causal inference, environmental mediation
- MeSH terms
- Adolescent, Adult, Alcohol Drinking, Attention Deficit Disorder with Hyperactivity, Child, Child, Preschool, Female, Health Surveys, Humans, Longitudinal Studies, Male, Pregnancy, Prenatal Exposure Delayed Effects, Risk Factors, United States, Conduct Disorder
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