The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
No-Mortality Liver Resection for Hepatocellular Carcinoma in Cirrhotic and Noncirrhotic Patients: Is There a Way? A Prospective Analysis of Our Approach
Abstract
BACKGROUND: Low resectability rates and significant morbidity and mortality rates often make surgery for hepatocellular carcinomas (HCCs) unfeasible. HYPOTHESIS: Our policy for surgical treatment of cirrhotic and noncirrhotic patients with HCC is adequate and safe. DESIGN: Prospective validation cohort study. SETTING: University hospital. PATIENTS: One hundred seven consecutive patients with HCCs. Associated cirrhosis was present in 64 (59.8%), and only 7 (6.5%) had normal livers. INTERVENTIONS: The presence of ascites, serum bilirubin level, and indocyanine green retention rate at 15 minutes were considered when selecting patients for surgery. Preoperative recovery of liver function was achieved with portal venous branch embolization, liver volumetry, bed rest, and control of serum aminotransferase levels. The surgical techniques mainly involved bloodless dissection using intraoperative ultrasonography and intermittent warm ischemia. The main perioperative care regimen was fresh frozen plasma infusion and strict limitation of blood transfusion. MAIN OUTCOME MEASURES: The 30-day postoperative mortality and morbidity rates. RESULTS: All the patients underwent surgery (37 major resections, 45 segmentectomies, and 25 limited resections), with no 30-day postoperative mortality, overall morbidity of 26.2%, and no major complications. Multiple logistic regression analysis revealed that only the type of operation was associated with a significantly higher morbidity risk (P = .05). CONCLUSION: With high resectability, low morbidity, and no mortality, our policy represents a solution to the drawbacks of surgical resection for treatment of HCCs, especially in patients with associated liver cirrhosis.
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NOTES ON THE ARREST OF HEPATIC HEMORRHAGE DUE TO TRAUMA
PRINGLE, J. H. (1908) · Annals of Surgery · doi:10.1097/00000658-190810000-00005 · Cited by 1,267
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Self-citationHepatocellular Carcinoma in Italian Patients with Cirrhosis
Colombo, M., de Franchis, R., Del Ninno, E., Sangiovanni, A., De Fazio, C., Tommasini, M., Donato, M. F., Piva, A., Di Carlo, V., & Dioguardi, N. (1991) · New England Journal of Medicine · doi:10.1056/nejm199109053251002 · Cited by 813
Surgery for small liver cancers
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Hepatic Resection Versus Transplantation for Hepatocellular Carcinoma
IWATSUKI, S., STARZL, T. E., SHEAHAN, D. G., YOKOYAMA, I., DEMETRIS, A. J., TODO, S., TZAKIS, A. G., VAN THIEL, D. H., CARR, B., SELBY, R., et al. (1991) · Annals of Surgery · doi:10.1097/00000658-199109000-00005 · Cited by 669
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Cited by
Resection and Liver Transplantation for Hepatocellular Carcinoma
Llovet, J. M., Schwartz, M., & Mazzaferro, V. (2005) · Seminars in Liver Disease · doi:10.1055/s-2005-871198 · Cited by 879
One Thousand Fifty-Six Hepatectomies Without Mortality in 8 Years
Imamura, H. (2003) · Archives of Surgery · doi:10.1001/archsurg.138.11.1198 · Cited by 835
Wei, A. C., Tung-Ping Poon, R., Fan, S.-T., & Wong, J. (2003) · Journal of British Surgery · doi:10.1002/bjs.4018 · Cited by 315
Enhanced-Reality Video Fluorescence: A Real-Time Assessment of Intestinal Viability
Diana, M., Noll, E., Diemunsch, P., Dallemagne, B., Benahmed, M. A., Agnus, V., Soler, L., Barry, B., Namer, I. J., Demartines, N., et al. (2014) · Annals of Surgery · doi:10.1097/sla.0b013e31828d4ab3 · Cited by 168
Metadata
- Authors
- Torzilli, G.
- Venue
- Archives of Surgery
- Publisher
- American Medical Association (AMA)
- Published
- 1999-09-01
- Volume
- 134
- Issue
- 9
- Pages
- 984
- ISSN
- 0004-0010 (ISSN-L)
- OpenAlex
- W2094466065
- Cited by
- 455
- References
- 31
- FWCI
- 8.29
- Type
- journal article
- Language
- en
- Open access
- closed
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- Torzilli, G. (1999). No-Mortality Liver Resection for Hepatocellular Carcinoma in Cirrhotic and Noncirrhotic Patients: Is There a Way? A Prospective Analysis of Our Approach. Archives of Surgery. https://doi.org/10.1001/archsurg.134.9.984
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