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Cited by 268

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Prospective Trial of Supranormal Values as Goals of Resuscitation in Severe Trauma

Fleming, Arthur·1992·Archives of Surgery

Abstract

We prospectively tested the effect of the early postinjury attainment of supranormal values of cardiac index (> or = 4.52 L/min per square meter), oxygen delivery (> or = 670 mL/min per square meter), and oxygen consumption (> or = 166 mL/min per square meter) on outcome in traumatized patients with an estimated blood loss of 2000 mL or more. The goals in control patients were to attain normal values for all hemodynamic measurements. During the 6-month period, 33 protocol patients and 34 control patients with similar vital signs, estimated blood losses, and severity of injuries were enrolled in the study. Eight (24%) protocol patients died, while 15 (44%) control patients died. The protocol patients had fewer mean (+/- SEM) organ failures per patient (0.76 +/- 1.21 vs 1.59 +/- 1.60), shorter stays in the intensive care unit (5 +/- 3 vs 12 +/- 12), and fewer mean days requiring ventilation (4 +/- 3 vs 11 +/- 10) than did the control patients (P < .05 for each). We conclude that attaining supranormal circulatory values improves survival and decreases morbidity in the severely traumatized patient.

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Metadata

Authors
Fleming, A.
Venue
Archives of Surgery
Published
1992-10-01
Volume
127
Issue
10
Pages
1175
ISSN
0004-0010 (ISSN-L)
OpenAlex
W2048069864
Cited by
268
References
5
FWCI
11.54
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Prospective Trial of Supranormal Values as Goals of Resuscitation in Severe Trauma. https://app.cochat.ai/papers/10.1001/archsurg.1992.01420100033006
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Fleming, A. (1992). Prospective Trial of Supranormal Values as Goals of Resuscitation in Severe Trauma. Archives of Surgery. https://doi.org/10.1001/archsurg.1992.01420100033006

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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