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THE PREVENTION AND ATTENUATION OF INFECTIOUS HEPATITIS BY GAMMA GLOBULIN: PRELIMINARY NOTE
Abstract
Infectious hepatitis (epidemic hepatitis, infective hepatitis) has been stated to be one of the most important diseases of the present war. 1 It has also been a serious problem in civilian populations throughout the world. Owing primarily to the lack of knowledge concerning the etiologic agent and its mode of transmission, adequate methods of prevention and control have not as yet been developed. It is our purpose in this preliminary report to present data which suggest that gamma globulin 2 from large pools of adult human serum may be effective in the control of certain epidemics of this disease. Parenteral injections of homologous blood products (whole blood, pooled plasma or serum, pooled measles and mumps convalescent plasma, and so on) have occasionally been followed by hepatitis. These blood products have usually been derived from single individuals or, in the case of pools, from relatively small numbers of young adults. The
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Cited by
Mascola, J. R., Lewis, M. G., Stiegler, G., Harris, D., VanCott, T. C., Hayes, D., Louder, M. K., Brown, C. R., Sapan, C. V., Frankel, S. S., et al. (1999) · Journal of Virology · doi:10.1128/jvi.73.5.4009-4018.1999 · Cited by 783
Cuthbert, J. A. (2001) · Clinical Microbiology Reviews · doi:10.1128/cmr.14.1.38-58.2001 · Cited by 469
Passive immunity in prevention and treatment of infectious diseases
Keller, M. A., & Stiehm, E. R. (2000) · Clinical Microbiology Reviews · doi:10.1128/cmr.13.4.602 · Cited by 388
Type A Viral Hepatitis: New Developments in an Old Disease
Lemon, S. M. (1985) · New England Journal of Medicine · doi:10.1056/nejm198510243131706 · Cited by 338
Hepatitis A in the Era of Vaccination
Wasley, A. (2006) · Epidemiologic Reviews · doi:10.1093/epirev/mxj012 · Cited by 295
Metadata
- Authors
- STOKES, J.
- Venue
- Journal of the American Medical Association
- Publisher
- American Medical Association (AMA)
- Published
- 1945-01-20
- Volume
- 127
- Issue
- 3
- Pages
- 144
- ISSN
- 0002-9955 (ISSN-L)
- OpenAlex
- W1963942448
- Cited by
- 290
- References
- 0
- FWCI
- 31.42
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: THE PREVENTION AND ATTENUATION OF INFECTIOUS HEPATITIS BY GAMMA GLOBULIN: PRELIMINARY NOTE. https://app.cochat.ai/papers/10.1001/jama.1945.02860030016004
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- STOKES, J. (1945). THE PREVENTION AND ATTENUATION OF INFECTIOUS HEPATITIS BY GAMMA GLOBULIN: PRELIMINARY NOTE. Journal of the American Medical Association. https://doi.org/10.1001/jama.1945.02860030016004
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
