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Cited by 182Viral Infections and Immunology ResearchVaccine Coverage and HesitancyVirology and Viral Diseases

The DOI matches its Crossref record.

LIVE, ORALLY GIVEN POLIOVIRUS VACCINE: EFFECTS OF RAPID MASS IMMUNIZATION ON POPULATION UNDER CONDITIONS OF MASSIVE ENTERIC INFECTION WITH OTHER VIRUSES

Sabin, Albert B.·1960·JAMA
DOI 10.1001/jama.1960.03020320001001
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Abstract

The phenomenon of viral interference must be taken into account in planning the use of live poliovirus vaccine in areas where conditions favor the extensive dissemination of naturally occurring polioviruses. Experience with feeding a trivalent vaccine to 26,033 children in a tropical city of 100, 000 population led to the conclusion that interference was overcome by mass feeding of vaccine to 86% of all children under 11 years within a period of about four days, and that, because dissemination of the poliovirus was self-limited, a second feeding of trivalent vaccine was necessary to achieve immunization of almost all children. Recommendations are here formulated for the eradication of poliomyelitis, but they apply only to subtropical and tropical regions with extensive dissemination of various enteric viruses and not to temperate zones with good sanitation and hygiene during certain periods of the year and under conditions of low or absent dissemination of enteric viruses.

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Crossref · 10.1001/jama.1960.03020320001001

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Metadata

Authors
Sabin, A. B.
Corresponding author
Sabin, Albert B.
Venue
JAMA
Publisher
American Medical Association (AMA)
Published
1960-08-06
Volume
173
Issue
14
Pages
1521
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
DOI
10.1001/jama.1960.03020320001001
OpenAlex
W2069543300
Cited by
182
References
0
Citations by year
2026: 1 · 2024: 2 · 2023: 4 · 2022: 3 · 2021: 3 · 2020: 1 · 2019: 3 · 2018: 16 · 2017: 4 · 2016: 5 · 2015: 3 · 2014: 11 · 2013: 4 · 2012: 4
FWCI
11.82
Type
journal article
Language
en
Open access
closed
Locations
  • JAMA (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Viral Infections and Immunology Research
  • Social Sciences › Health › Vaccine Coverage and Hesitancy
  • Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
Keywords
live poliovirus vaccine, viral interference, trivalent oral polio vaccine, polio eradication, mass vaccination campaigns, enteric viruses, tropical and subtropical regions
MeSH terms
Humans, Poliomyelitis, Viruses, Mass Vaccination

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