The DOI matches its Crossref record.
Clinical Science
Abstract
The Inflammatory Reaction to Sodium Urate Its Possible Relationship to the Genesis of Acute Gouty Arthritis J. E. Seegmiller, M.D., R. Rodney Howell, M.D., and Stephen E. Malawista, M.D., Bethesda, Md. A CUTE GOUTY ARTHRITIS is a dramatic but relatively uncommon accompaniment of hyperuricemia. Multiple etiologies for the hyperuricemia of primary gout have been defined in recent years.2,3During this time, however, the mechanism of acute gouty arthritis has been studied relatively little, with the exception of a notation of the increased urinary excretion of certain purine compounds during the attack.4Today the origin and development of acute gouty arthritis remains an enigma. The reputed inertness of sodium urate upon injection into the human has been a primary argument against assigning a role to this substance in the genesis of acute gouty arthritis.5Since most previous work has been done with solutions of sodium urate, we have
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Hyperuricemia and Gout: Classification, Complications and Management
Boss, G. R., & Seegmiller, J. E. (1979) · New England Journal of Medicine · doi:10.1056/nejm197906283002604 · Cited by 281
Hsu, D.-Z., Chen, S.-J., Chu, P.-Y., & Liu, M.-Y. (2013) · SpringerPlus · doi:10.1186/2193-1801-2-659 · Cited by 47
Metadata
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 1962-05-12
- Volume
- 180
- Issue
- 6
- Pages
- 469
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2603461932
- Cited by
- 222
- References
- 0
- FWCI
- 16.12
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Clinical Science. https://app.cochat.ai/papers/10.1001/jama.1962.03050190031006
- The paper
- Clinical Science. (1962). JAMA. https://doi.org/10.1001/jama.1962.03050190031006
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
