L-Asparaginase Therapy for Leukemia and Other Malignant Neoplasms: Remission in Human Leukemia
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Asparagine is crucial for tumor survival and metastasis.
“Although the clinical effect of l-asparaginase clearly indicates that asparagine is crucial for tumor survival and metastasis52, the importance of asparagine beyond protein synthesis and the mechanism by which asparagine supplementation enhances glutamine-associated metabolism are less well understood.”
From Glutamine reliance in cell metabolism (2020) · cites this paper as [52]
Depletion of plasma asparagine by recombinant bacterial L-Asparaginase is effective anticancer intervention for acute lymphoblastic leukemia.
“Depletion of plasma asparagine by a recombinant form of bacterial L-Asparaginase is an effective anticancer intervention for this cancer type (Hill et al., 1967; Pieters et al., 2011).”
From The emerging hallmarks of cancer metabolism (2016) · cites this paper as Hill et al., 1967
Cited by
Sorted by citations
The emerging hallmarks of cancer metabolism
Pavlova, N. N., & Thompson, C. B. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2015.12.006 · Cited by 5,926 · see citing works
Glutamine reliance in cell metabolism
Yoo, H. C., Yu, Y. C., Sung, Y., & Han, J. M. (2020) · Experimental & Molecular Medicine · doi:10.1038/s12276-020-00504-8 · Cited by 1,021 · see citing works
- Authors
- Hill, J. M.
- Corresponding author
- Hill, Joseph M.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 1967-11-27
- Volume
- 202
- Issue
- 9
- Pages
- 882
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W7214231115
- Cited by
- 1
- References
- 0
- Citations by year
- 2020: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Acute Lymphoblastic Leukemia research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Amino Acid Enzymes and Metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Cancer Research and Treatments
- Keywords
- L-asparaginase, leukemia, cancer, chemotherapy, asparaginase therapy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
