Cited by 3Blood Pressure and Hypertension StudiesAcute Ischemic Stroke ManagementCardiovascular Health and Disease Prevention

The DOI matches its Crossref record.

Epidemiologic Assessment of the Role of Blood Pressure in Stroke: The Framingham Study

Kannel, William B.·1970·JAMA

Abstract

Control of hypertension, labile or fixed, systolic or diastolic, at any age, in either sex appears to be central to prevention of atherothrombotic brain infarction (ABI). Prospectively, hypertension proved the most common and potent precursor of ABI's. Its contribution was direct and could not be attributed to factors related both to stroke and hypertension. Asymptomatic, causal "hypertension" was associated with a risk of ABI about four times that of normotensives. The probability of occurrence of an ABI was predicted no better with both blood pressure measurements or the mean arterial pressure than with systolic alone. Since there was no diminishing impact of systolic pressure with advancing age, the concept that systolic elevations are, even in the aged, innocuous is premature. Comparing normotensives and hypertensives in each sex, women did not tolerate hypertension better than men.

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Crossref · 10.1001/jama.1970.03180020021004

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Metadata

Authors
Kannel, W. B.
Corresponding author
Kannel, William B.
Venue
JAMA
Published
1970-10-12
Volume
214
Issue
2
Pages
301
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
OpenAlex
W7214241799
Cited by
2
References
0
FWCI
0.55
Type
journal article
Language
en
Open access
closed
Locations
JAMA (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
Keywords
hypertension, stroke, atherothrombotic brain infarction, blood pressure, systolic blood pressure, mean arterial pressure, asymptomatic hypertension, stroke risk factors, sex differences, aging, hypertension control

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