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Cited by 368

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A Meta-analysis of Alcohol Consumption in Relation to Risk of Breast Cancer

Longnecker, Matthew P.·1988·JAMA: The Journal of the American Medical Association

Abstract

Epidemiologic findings regarding the relation between alcohol consumption and risk of breast cancer have been inconsistent. We performed a meta-analysis (a quantitative review) of the available data. To evaluate whether there was a dose-response relation between alcohol consumption and risk of breast cancer, we fitted mathematical models to the pooled data. There was strong evidence to support a dose-response relation in both the case-control and follow-up epidemiologic data. Using the dose-response curves that we calculated, the risk of breast cancer at an alcohol intake of 24 g (1 oz) of absolute alcohol daily (about two drinks daily) relative to nondrinkers was 1.4 (95% confidence interval, 1.0 to 1.8) in the case-control data and was 1.7 (95% confidence interval, 1.4 to 2.2) in the follow-up data. We interpret these findings not as proof of causality, but as strongly supportive of an association between alcohol consumption and risk of breast cancer.

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Metadata

Authors
Longnecker, M. P.
Venue
JAMA: The Journal of the American Medical Association
Published
1988-08-05
Volume
260
Issue
5
Pages
652
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
OpenAlex
W2052044976
Cited by
368
References
1
FWCI
6.38
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A Meta-analysis of Alcohol Consumption in Relation to Risk of Breast Cancer. https://app.cochat.ai/papers/10.1001/jama.1988.03410050072032
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Longnecker, M. P. (1988). A Meta-analysis of Alcohol Consumption in Relation to Risk of Breast Cancer. JAMA: The Journal of the American Medical Association. https://doi.org/10.1001/jama.1988.03410050072032

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