The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
A Prospective Study of the Outcome for Fetuses With Diaphragmatic Hernia
Abstract
OBJECTIVE: To establish the natural history and outcome of isolated congenital diaphragmatic hernia (CDH) diagnosed before birth. The mortality of CDH with currently available postnatal care, including extracorporeal membrane oxygenation (ECMO), reported in retrospective studies ranges from less than 25% to greater than 75%. This variation is attributable to a "hidden mortality" (infants who die with CDH that is not recognized) of unknown magnitude. DESIGN: Prospectively followed case series. SETTING: Patients were referred from practitioners in 18 states and evaluated and followed up by the University of California, San Francisco, Fetal Treatment Center. Arrangements were made for planned delivery at tertiary perinatal centers with ECMO capability. PATIENTS: All 83 fetuses with isolated, potentially correctable CDH diagnosed prior to 24 weeks' gestation referred to the University of California, San Francisco, Fetal Treatment Center between January 1989 and October 1993. MAIN OUTCOME MEASURES: Survival beyond 2 months after optimal postnatal care. RESULTS: Fifty-eight percent (48 of 83) died despite optimal postnatal care (95% confidence interval, 41% to 75%). Of the 48 nonsurvivors, seven suffered intrauterine fetal demise, four were too premature for ECMO, 16 died before ECMO could be started, and 21 died despite ECMO therapy. Twenty-two of the 35 survivors received ECMO, and nine of these have severe chronic illness attributable to the intensive management. CONCLUSIONS: In this study, the mortality for potentially correctable CDH diagnosed before 24 weeks' gestation is 58%, despite optimal care presently available after birth. Infants who die in utero and soon after birth constitute a substantial hidden mortality.
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Statistical Methods for Rates and Proportions
Fleiss, J. L., Levin, B., & Paik, M. C. (2003) · Wiley Series in Probability and Statistics · doi:10.1002/0471445428 · Cited by 18,646
Correction of congenital diaphragmatic hernia in utero: VI. hard-earned lessons
Harrison, M. R., Adzick, N. S., Flake, A. W., Jennings, R. W., Estes, J. M., MacGillivray, T. E., Chueh, J. T., Goldberg, J. D., Filly, R. A., Goldstein, R. B., et al. (1993) · Journal of Pediatric Surgery · doi:10.1016/s0022-3468(05)80338-0 · Cited by 396
Self-citationDiaphragmatic hernia in the fetus: Prenatal diagnosis and outcome in 94 cases
Adzick, N. S., Harrison, M. R., Glick, P. L., Nakayama, D. K., Manning, F. A., & deLorimier, A. A. (1985) · Journal of Pediatric Surgery · doi:10.1016/s0022-3468(85)80219-0 · Cited by 377
Self-citationA population‐based study of congenital diaphragmatic hernia
Torfs, C. P., Curry, C. J. R., Bateson, T. F., & Honoré, L. H. (1992) · Teratology · doi:10.1002/tera.1420460605 · Cited by 329
Congenital diaphragmatic hernia: The hidden mortality
Harrison, M. R., Bjordal, R. I., Langmark, F., & Knutrud, O. (1978) · Journal of Pediatric Surgery · doi:10.1016/s0022-3468(78)80391-1 · Cited by 320
Self-citationHarrison, M. R., Adzick, N. S., Longaker, M. T., Goldberg, J. D., Rosen, M. A., Filly, R. A., Evans, M. I., & Golbus, M. S. (1990) · New England Journal of Medicine · doi:10.1056/nejm199005313222207 · Cited by 299
Self-citationAntenatal intervention for congenital cystic adenomatoid malformation
Harrison, M. R., Adzick, N. S., Jennings, R. W., et al. (1990) · The Lancet · doi:10.1016/0140-6736(90)92420-m · Cited by 151
Self-citationA five-year statewide experience with congenital diaphragmatic hernia
Wenstrom, K. D., Weiner, C. P., & Hanson, J. W. (1991) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(91)90425-q · Cited by 107
Thorpe‐Beeston, J. G., Gosden, C. M., & Nicolaides, K. H. (1989) · Fetal Diagnosis and Therapy · doi:10.1159/000263386 · Cited by 71
Cited by
Sonographic predictors of survival in fetal diaphragmatic hernia
Metkus, A. P., Filly, R. A., Stringer, M. D., Harrison, M. R., & Adzick, N. S. (1996) · Journal of Pediatric Surgery · doi:10.1016/s0022-3468(96)90338-3 · Cited by 658
Self-citationInhaled Nitric Oxide and Hypoxic Respiratory Failure in Infants With Congenital Diaphragmatic Hernia
The Neonatal Inhaled Nitric Oxide Study Group (NINOS) (1997) · Pediatrics · doi:10.1542/peds.99.6.838 · Cited by 455
Congenital Diaphragmatic Hernia
Langham, M. R., Kays, D. W., Ledbetter, D. J., Frentzen, B., Sanford, L. L., & Richards, D. S. (1996) · Clinics in Perinatology · doi:10.1016/s0095-5108(18)30201-x · Cited by 346
Plug the lung until it grows (PLUG): A new method to treat congenital diaphragmatic hernia in utero
Hedrick, M. H., Estes, J. M., Sullivan, K. M., Bealer, J. F., Kitterman, J. A., Flake, A. W., Scott Adzick, N., & Harrison, M. R. (1994) · Journal of Pediatric Surgery · doi:10.1016/0022-3468(94)90724-2 · Cited by 314
Self-citationPrenatal diagnosis of severe structural congenital malformations in Europe
Garne, E., Loane, M., Dolk, H., De Vigan, C., Scarano, G., Tucker, D., Stoll, C., Gener, B., Pierini, A., Nelen, V., et al. (2005) · Ultrasound in Obstetrics & Gynecology · doi:10.1002/uog.1784 · Cited by 293
Metadata
- Authors
- Harrison, M. R.
- Venue
- JAMA: The Journal of the American Medical Association
- Publisher
- American Medical Association (AMA)
- Published
- 1994-02-02
- Volume
- 271
- Issue
- 5
- Pages
- 382
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2091142227
- Cited by
- 355
- References
- 9
- FWCI
- 20.58
- Type
- journal article
- Language
- en
- Open access
- closed
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