The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Brain Infarction and the Clinical Expression of Alzheimer Disease
Abstract
To the Editor. —Dr Snowdon and colleagues 1 emphasized the important contribution of lacunar infarcts to cognitive decline in patients with AD. However, with few exceptions, no clear correlation exists between location or number of lacunar infarcts and development of vascular dementia. 2,3 More than a direct cause of dementia, lacunar infarcts per se probably represent a surrogate or a marker for small-vessel disease(arteriolosclerosis) leading also to periventricular ischemic white matter disease in the elderly. 4 These lesions, rediscovered by brain imaging techniques under the name leukoaraiosis, constitute the pathological substratum of Binswanger disease, 5 a vascular form of senile dementia. Moreover, Brun and Englund 6 demonstrated these lesions in about 60% of patients with AD. However, periventricular ischemic white matter lesions in the elderly may be undetectable to the naked eye examination of the brain
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Citations
Cites
Senile Dementia of the Binswanger Type: A Vascular Form of Dementia in the Elderly
Román, G. C. (1987) · JAMA · doi:10.1001/jama.1987.03400130096040 · Cited by 372
Self-citation
Cited by
Wardlaw, J. M., Smith, E. E., Biessels, G. J., Cordonnier, C., Fazekas, F., Frayne, R., Lindley, R. I., O'Brien, J. T., Barkhof, F., Benavente, O. R., et al. (2013) · The Lancet Neurology · doi:10.1016/s1474-4422(13)70124-8 · Cited by 5,544
Neurovascular pathways to neurodegeneration in Alzheimer’s disease and other disorders
Zlokovic, B. V. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3114 · Cited by 2,969
The clinical use of structural MRI in Alzheimer disease
Frisoni, G. B., Fox, N. C., Jack, C. R., Scheltens, P., & Thompson, P. M. (2010) · Nature Reviews Neurology · doi:10.1038/nrneurol.2009.215 · Cited by 2,113
Hachinski, V., Iadecola, C., Petersen, R. C., Breteler, M. M., Nyenhuis, D. L., Black, S. E., Powers, W. J., DeCarli, C., Merino, J. G., Kalaria, R. N., et al. (2006) · Stroke · doi:10.1161/01.str.0000237236.88823.47 · Cited by 1,722
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
Bell, R. D., Winkler, E. A., Singh, I., Sagare, A. P., Deane, R., Wu, Z., Holtzman, D. M., Betsholtz, C., Armulik, A., Sallstrom, J., et al. (2012) · Nature · doi:10.1038/nature11087 · Cited by 1,293
Metadata
- Authors
- Roman, G. C.
- Venue
- JAMA: The Journal of the American Medical Association
- Publisher
- American Medical Association (AMA)
- Published
- 1997-07-09
- Volume
- 278
- Issue
- 2
- Pages
- 113
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2064184881
- Cited by
- 350
- References
- 1
- FWCI
- 8.43
- Type
- journal article
- Language
- en
- Open access
- closed
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- Roman, G. C. (1997). Brain Infarction and the Clinical Expression of Alzheimer Disease. JAMA: The Journal of the American Medical Association. https://doi.org/10.1001/jama.1997.03550020045023
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
