The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity
Open accessAbstract
CONTEXT: Very preterm infants are prone to apnea and have an increased risk of death or disability. Caffeine therapy for apnea of prematurity reduces the rates of cerebral palsy and cognitive delay at 18 months of age. OBJECTIVE: To determine whether neonatal caffeine therapy has lasting benefits or newly apparent risks at early school age. DESIGN, SETTING, AND PARTICIPANTS: Five-year follow-up from 2005 to 2011 in 31 of 35 academic hospitals in Canada, Australia, Europe, and Israel, where 1932 of 2006 participants (96.3%) had been enrolled in the randomized, placebo-controlled Caffeine for Apnea of Prematurity trial between 1999 and 2004. A total of 1640 children (84.9%) with birth weights of 500 to 1250 g had adequate data for the main outcome at 5 years. MAIN OUTCOME MEASURES: Combined outcome of death or survival to 5 years with 1 or more of motor impairment (defined as a Gross Motor Function Classification System level of 3 to 5), cognitive impairment (defined as a Full Scale IQ<70), behavior problems, poor general health, deafness, and blindness. RESULTS: The combined outcome of death or disability was not significantly different for the 833 children assigned to caffeine from that for the 807 children assigned to placebo (21.1% vs 24.8%; odds ratio adjusted for center, 0.82; 95% CI, 0.65-1.03; P = .09). The rates of death, motor impairment, behavior problems, poor general health, deafness, and blindness did not differ significantly between the 2 groups. The incidence of cognitive impairment was lower at 5 years than at 18 months and similar in the 2 groups (4.9% vs 5.1%; odds ratio adjusted for center, 0.97; 95% CI, 0.61-1.55; P = .89). CONCLUSION: Neonatal caffeine therapy was no longer associated with a significantly improved rate of survival without disability in children with very low birth weights who were assessed at 5 years.
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Palisano, R., Rosenbaum, P., Walter, S., Russell, D., Wood, E., & Galuppi, B. (1997) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1997.tb07414.x · Cited by 6,721
Neurologic and Developmental Disability at Six Years of Age after Extremely Preterm Birth
Marlow, N., Wolke, D., Bracewell, M. A., & Samara, M. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa041367 · Cited by 1,901
A New and Improved Population-Based Canadian Reference for Birth Weight for Gestational Age
Kramer, M. S., Platt, R. W., Wen, S. W., Joseph, K. S., Allen, A., Abrahamowicz, M., Blondel, B., Bréart, G., & for the Fetal/Infant Health Study Group of the Canadian Perinatal Surveillance System (2001) · Pediatrics · doi:10.1542/peds.108.2.e35 · Cited by 1,524
Manual for the Bayley Scales of Infant Development
Bayley, N. (1969) · Medical Entomology and Zoology · Cited by 1,328
Caffeine Therapy for Apnea of Prematurity
Schmidt, B., Roberts, R. S., Davis, P., Doyle, L. W., Barrington, K. J., Ohlsson, A., Solimano, A., & Tin, W. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa054065 · Cited by 1,208
Self-citationLong-Term Effects of Caffeine Therapy for Apnea of Prematurity
Schmidt, B., Roberts, R. S., Davis, P., Doyle, L. W., Barrington, K. J., Ohlsson, A., Solimano, A., & Tin, W. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa073679 · Cited by 948
Self-citationAggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor
Ledent, C., Vaugeois, J.-M., Schiffmann, S. N., Pedrazzini, T., Yacoubi, M. E., Vanderhaeghen, J.-J., Costentin, J., Heath, J. K., Vassart, G., & Parmentier, M. (1997) · Nature · doi:10.1038/41771 · Cited by 918
Developmental Test of Visual-Motor Integration
Beery, K. E., & Buktenica, N. A. (2012) · PsycTESTS Dataset · doi:10.1037/t11054-000 · Cited by 666
Hack, M., Taylor, H. G., Drotar, D., Schluchter, M., Cartar, L., Wilson-Costello, D., Klein, N., Friedman, H., Mercuri-Minich, N., & Morrow, M. (2005) · Pediatrics · doi:10.1542/peds.2005-0173 · Cited by 605
de Kieviet, J. F., Piek, J. P., Aarnoudse-Moens, C. S., & Oosterlaan, J. (2009) · JAMA · doi:10.1001/jama.2009.1708 · Cited by 523
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Bronchopulmonary Dysplasia: Executive Summary of a Workshop
Higgins, R. D., Jobe, A. H., Koso-Thomas, M., Bancalari, E., Viscardi, R. M., Hartert, T. V., Ryan, R. M., Kallapur, S. G., Steinhorn, R. H., Konduri, G. G., et al. (2018) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2018.01.043 · Cited by 956
Pierrat, V., Marchand-Martin, L., Arnaud, C., Kaminski, M., Resche-Rigon, M., Lebeaux, C., Bodeau-Livinec, F., Morgan, A. S., Goffinet, F., Marret, S., et al. (2017) · BMJ · doi:10.1136/bmj.j3448 · Cited by 482
A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants
Juul, S. E., Comstock, B. A., Wadhawan, R., Mayock, D. E., Courtney, S. E., Robinson, T., Ahmad, K. A., Bendel-Stenzel, E., Baserga, M., LaGamma, E. F., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa1907423 · Cited by 325
Serenius, F., Ewald, U., Farooqi, A., Fellman, V., Hafström, M., Hellgren, K., Maršál, K., Ohlin, A., Olhager, E., Stjernqvist, K., et al. (2016) · JAMA Pediatrics · doi:10.1001/jamapediatrics.2016.1210 · Cited by 310
The complex aetiology of cerebral palsy
Korzeniewski, S. J., Slaughter, J., Lenski, M., Haak, P., & Paneth, N. (2018) · Nature Reviews Neurology · doi:10.1038/s41582-018-0043-6 · Cited by 264
Metadata
- Authors
- Schmidt, B.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2012-01-18
- Volume
- 307
- Issue
- 3
- Pages
- 275
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2159615203
- Cited by
- 403
- References
- 26
- FWCI
- 30.43
- Type
- journal article
- Language
- en
- Open access
- green
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