Quality of Life After PCI vs CABG Among Patients With Diabetes and Multivessel Coronary Artery Disease: A Randomized Clinical Trial
Open accessAbstract
IMPORTANCE: The FREEDOM trial demonstrated that among patients with diabetes mellitus and multivessel coronary artery disease, coronary artery bypass graft (CABG) surgery resulted in lower rates of death and myocardial infarction but a higher risk of stroke when compared with percutaneous coronary intervention (PCI) using drug-eluting stents. Whether there are treatment differences in health status, as assessed from the patient's perspective, is unknown. OBJECTIVES: To compare the relative effects of CABG vs PCI using drug-eluting stents on health status among patients with diabetes mellitus and multivessel coronary artery disease. DESIGN, SETTING, AND PARTICIPANTS: Between 2005 and 2010, 1900 patients from 18 countries with diabetes mellitus and multivessel coronary artery disease were randomized to undergo either CABG surgery (n = 947) or PCI (n = 953) as an initial treatment strategy. Of these, a total of 1880 patients had baseline health status assessed (935 CABG, 945 PCI) and comprised the primary analytic sample. INTERVENTIONS: Initial revascularization with CABG surgery or PCI. MAIN OUTCOMES AND MEASURES: Health status was assessed using the angina frequency, physical limitations, and quality-of-life domains of the Seattle Angina Questionnaire at baseline, at 1, 6, and 12 months, and annually thereafter. For each scale, scores range from 0 to 100 with higher scores representing better health. The effect of CABG surgery vs PCI was evaluated using longitudinal mixed-effect models. RESULTS: At baseline, mean (SD) scores for the angina frequency, physical limitations, and quality-of-life subscales of the Seattle Angina Questionnaire were 70.9 (25.1), 67.3 (24.4), and 47.8 (25.0) for the CABG group and 71.4 (24.7), 69.9 (23.2), and 49.2 (25.7) for the PCI group, respectively. At 2-year follow-up, mean (SD) scores were 96.0 (11.9), 87.8 (18.7), and 82.2 (18.9) after CABG and 94.7 (14.3), 86.0 (19.3), and 80.4 (19.6) after PCI, with significantly greater benefit of CABG on each domain (mean treatment benefit, 1.3 [95% CI, 0.3-2.2], 4.4 [95% CI, 2.7-6.1], and 2.2 [95% CI, 0.7-3.8] points, respectively; P < .01 for each comparison). Beyond 2 years, the 2 revascularization strategies provided generally similar patient-reported outcomes. CONCLUSIONS AND RELEVANCE: For patients with diabetes and multivessel CAD, CABG surgery provided slightly better intermediate-term health status and quality of life than PCI using drug-eluting stents. The magnitude of benefit was small, without consistent differences beyond 2 years, in part due to the higher rate of repeat revascularization with PCI. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00086450.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
FREEDOM also found a small quality-of-life benefit favoring CABG from 6 months to 2 years, with no further gain after 2 years.
“There was also a small favorable benefit in quality of life favoring CABG from 6 months to 2 years, although there was no further accrual of benefit beyond 2 years.294”
From Clinical management of stable coronary artery disease in patients with type 2 diabetes mellitus: a scientific statement from the American Heart Association (2020) · cites this paper as [294]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Serruys, P., de Jaegere, P., Kiemeneij, F., Macaya, C., Rutsch, W., Heyndrickx, G., Emanuelsson, H., Marco, J., Legrand, V., & Materne, P. (1994) · New England Journal of Medicine · doi:10.1056/nejm199408253310801 · Cited by 4,695 · see citing works
Serruys, P., Morice, M., Kappetein, A., Colombo, A., Holmes, D., Mack, M., Ståhle, E., Feldman, T., van den Brand, M. V. D., Bass, E., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0804626 · Cited by 4,142 · see citing works
Strategies for Multivessel Revascularization in Patients with Diabetes
Farkouh, M. E., Domanski, M., Sleeper, L. A., Siami, F. S., Dangas, G., Mack, M., Yang, M., Cohen, D. J., Rosenberg, Y., Solomon, S. D., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1211585 · Cited by 1,922 · see citing works
Comparison of coronary bypass surgery with angioplasty in patients with multivessel disease.
Bourassa, M., Frye, R., King, S., Detre, K., Alderman, E., Andrews, K., & Sopko, G. (1996) · New England Journal of Medicine · doi:10.1056/nejm199607253350401 · Cited by 1,489 · see citing works
Spertus, J., Winder, J. A., Dewhurst, T. A., Deyo, R., Prodzinski, J., McDonnell, M., & Fihn, S. (1995) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(94)00397-9 · Cited by 1,413 · see citing works
Unbalanced repeated-measures models with structured covariance matrices.
Jennrich, R., & Schluchter, M. (1986) · Biometrics · doi:10.2307/2530695 · Cited by 1,382 · see citing works
Comparison of coronary-artery bypass surgery and stenting for the treatment of multivessel disease.
Serruys, P., Unger, F., Sousa, J., Jatene, A., Bonnier, H., Schönberger, J. P. M. A., Buller, N., Bonser, R., van den Brand, M. V. D., van Herwerden, L. A., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200104123441502 · Cited by 1,204 · see citing works
Appointment of New Associate Editor for Circulation
Willerson, J. (1996) · Circulation · doi:10.1161/01.cir.94.6.1193 · Cited by 918 · see citing works
Everolimus-eluting versus paclitaxel-eluting stents in coronary artery disease.
Stone, G., Rizvi, A., Newman, W., Mastali, K., Wang, J., Caputo, R. P., Doostzadeh, J., Cao, S., Simonton, C., Sudhir, K., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0910496 · Cited by 907 · see citing works
Kedhi, E., Joesoef, K. S., Mcfadden, E., Wassing, J., Mieghem, C. V., Goedhart, D., & Smits, P. (2010) · The Lancet · doi:10.1016/s0140-6736(09)62127-9 · Cited by 717 · see citing works
Effect of PCI on quality of life in patients with stable coronary disease.
Weintraub, W., Spertus, J., Kolm, P., Maron, D., Zhang, Z.-F., Jurkovitz, C., Zhang, W., Hartigan, P., Lewis, C., Veledar, E., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa072771 · Cited by 673 · see citing works
Serruys, P., Ong, A. T. L., van Herwerden, L. A., Sousa, J., Jatene, A., Bonnier, J., Schönberger, J. P. M. A., Buller, N., Bonser, R., Disco, C., et al. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.12.082 · Cited by 657 · see citing works
Health Status Predicts Long-Term Outcome in Outpatients With Coronary Disease
Spertus, J., Jones, P. G., McDonell, M., Fan, V., & Fihn, S. (2002) · Circulation · doi:10.1161/01.cir.0000020688.24874.90 · Cited by 528 · see citing works
Kapur, A., Hall, R., Malik, I., Qureshi, A., Butts, J. N., de Belder, M. D., Baumbach, A., Angelini, G., de Belder, A. D., Oldroyd, K., et al. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.10.014 · Cited by 497 · see citing works
Hoffman, S. N., Tenbrook, J., Wolf, M. P., Pauker, S., Salem, D., & Wong, J. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(03)00157-8 · Cited by 455 · see citing works
Monitoring the quality of life in patients with coronary artery disease.
Spertus, J. A., Winder, J. A., Dewhurst, T. A., Deyo, R., & Fihn, S. D. (1994) · American Journal of Cardiology · doi:10.1016/0002-9149(94)90555-x · Cited by 435 · see citing works
Preferences for quality of life or survival expressed by patients with heart failure
Lewis, E. F., Johnson, P. A., Johnson, W., Collins, C., Griffin, L., & Stevenson, L. W. (2001) · The Journal of Heart and Lung Transplantation · doi:10.1016/s1053-2498(01)00298-4 · Cited by 433 · see citing works
Hlatky, M., Rogers, W. J., Johnstone, I., Boothroyd, D., Brooks, M. M., Pitt, B., Reeder, G., Ryan, T., Smith, H. C., Whitlow, P., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199701093360203 · Cited by 328 · see citing works
Quality of Life after PCI with Drug-Eluting Stents or Coronary-Artery Bypass Surgery
Cohen, D. J., Van Hout, B., Serruys, P. W., Mohr, F. W., Macaya, C., den Heijer, P., Vrakking, M. M., Wang, K., Mahoney, E. M., Audi, S., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1001508 · Cited by 288 · see citing works
Legrand, V., Serruys, P., Unger, F., van Hout, B., Vrolix, M., Fransen, G., Nielsen, T., Paulsen, P. K., Gomes, R., Melo, J. M. G. D. Q. E., et al. (2004) · Circulation · doi:10.1161/01.cir.0000118504.61212.4b · Cited by 246
Henderson, R., Pocock, S., Sharp, S., Nanchahal, K., Sculpher, M., Buxton, M., & Hampton, J. (1998) · The Lancet · doi:10.1016/s0140-6736(98)03358-3 · Cited by 244 · see citing works
Bangalore, S., Kumar, S. K., Fusaro, M. V., Amoroso, N., Kirtane, A., Byrne, R., Williams, D., Slater, J., Cutlip, D., & Feit, F. (2012) · British medical journal · doi:10.1136/bmj.e5170 · Cited by 230 · see citing works
Evidence for Use of Coronary Stents: A Hierarchical Bayesian Meta-Analysis
Brophy, J., Belisle, P., & Joseph, L. (2003) · Annals of Internal Medicine · doi:10.7326/0003-4819-138-10-200305200-00005 · Cited by 208 · see citing works
Farkouh, M., Dangas, G., Leon, M., Smith, C. R., Nesto, R., Buse, J., Cohen, D., Mahoney, E., Sleeper, L., King, S., et al. (2008) · American Heart Journal · doi:10.1016/j.ahj.2007.10.012 · Cited by 198 · see citing works
Strategies for multivessel revascularization in patients with diabetes.
Lee, J.-H., & Lee, S.-W. (2013) · Journal of Comparative Effectiveness Research · doi:10.2217/cer.13.21 · Cited by 197 · see citing works
Quantifying and predicting recovery after heart surgery.
Jenkins, C., Stanton, B., & Jono, R. T. (1994) · Psychosomatic Medicine · doi:10.1097/00006842-199405000-00005 · Cited by 123 · see citing works
Magnuson, E., Farkouh, M., Fuster, V., Wang, K.-J., Vilain, K. A., Li, H., Appelwick, J., Muratov, V., Sleeper, L., Boineau, R., et al. (2012) · Circulation · doi:10.1161/circulationaha.112.147488 · Cited by 122 · see citing works
Self-citationRose, J., O'Toole, E., Dawson, N., Lawrence, R., Gurley, D., Thomas, C. L., Hamel, M., & Cohen, H. (2004) · Journal of Clinical Oncology · doi:10.1200/jco.2004.06.050 · Cited by 119 · see citing works
Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D).
Sinha, A. (2013) · doi:10.1016/j.ihj.2013.04.027 · Cited by 104
Zhang, Z.-F., Mahoney, E., Stables, R., Booth, J., Nugara, F., Spertus, J., & Weintraub, W. (2003) · Circulation · doi:10.1161/01.cir.0000087600.83707.fd · Cited by 102 · see citing works
Höfer, S., Benzer, W., Schüssler, G., von Steinbüchel, N., & Oldridge, N. (2003) · Quality of Life Research · doi:10.1023/a:1022272620947 · Cited by 95 · see citing works
Borkon, A., Muehlebach, G., House, J., Marso, S., & Spertus, J. (2002) · Annals of Thoracic Surgery · doi:10.1016/s0003-4975(02)04063-8 · Cited by 84 · see citing works
Arnold, S., Spertus, J., Jones, P. G., Xiao, L., & Cohen, D. (2009) · American Heart Journal · doi:10.1016/j.ahj.2009.03.021 · Cited by 65 · see citing works
Cleary, P., Epstein, A. M., Oster, G., Morrissey, G., Stason, W. B., Debussey, S., Plachetka, J., & Zimmerman, M. (1991) · Medical Care · doi:10.1097/00005650-199110000-00001 · Cited by 65 · see citing works
Brooks, M. M., Chung, S., Helmy, T. A., Hillegass, W. B., Escobedo, J., Melsop, K. A., Massaro, E. M., McBane, R. D., Hyde, P., Hlatky, M. A., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.912642 · Cited by 45 · see citing works
Arnold, S., Magnuson, E., Wang, K.-J., Serruys, P., Kappetein, A., Mohr, F., & Cohen, D. J. (2012) · Circulation. Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.111.964585 · Cited by 36 · see citing works
Compelling evidence for coronary-bypass surgery in patients with diabetes.
Hlatky, M. (2012) · New England Journal of Medicine · doi:10.1056/nejme1212278 · Cited by 32 · see citing works
Evidence for use of coronary stents.
Massel, D. (2004) · Annals of Internal Medicine · doi:10.7326/0003-4819-140-2-200401200-00032-w1 · Cited by 8
Flagged first, then by citations
5 of the 43 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
2018 ESC/EACTS guidelines on myocardial revascularization
Neumann, F.-J., Sousa-Uva, M., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehy394 · Cited by 7,167 · see citing works
2014 ESC/EACTS Guidelines on myocardial revascularization
Kolh, P. H., Windecker, S., Alfonso, F., Collet, J., Cremer, J., Falk, V., Filippatos, G. S., Hamm, C. W., Head, S. J., Jüni, P., et al. (2014) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezu366 · Cited by 4,211 · see citing works
2018 ESC/EACTS Guidelines on myocardial revascularization
Sousa-Uva, M., Neumann, F., Ahlsson, A., Alfonso, F., BANNING, A. P., Benedetto, U., Byrne, R. A., Collet, J., Falk, V., Head, S. J., et al. (2018) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezy289 · Cited by 1,015 · see citing works
Virani, S. S., Newby, L. K., Arnold, S. V., Bittner, V., Brewer, L. C., Demeter, S. H., Dixon, D. L., Fearon, W. F., Hess, B., Johnson, H. M., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001168 · Cited by 1,598 · see citing works
2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization
Lawton, J. S., Tamis‐Holland, J. E., Bangalore, S., Bates, E., Beckie, T. M., Bischoff, J. M., Bittl, J. A., Cohen, M. G., DiMaio, J. M., Don, C. W., et al. (2021) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2021.09.006 · Cited by 1,651 · see citing works
Coronary Microvascular Disease Pathogenic Mechanisms and Therapeutic Options
Taqueti, V. R., & Carli, M. F. D. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.09.042 · Cited by 797 · see citing works
Virani, S. S., Newby, L. K., Arnold, S. V., Bittner, V., Brewer, L. C., Demeter, S. H., Dixon, D. L., Fearon, W. F., Hess, B., Johnson, H. M., et al. (2023) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2023.04.003 · Cited by 596 · see citing works
Arnold, S. V., Bhatt, D. L., Barsness, G. W., Beatty, A. L., Deedwania, P. C., Inzucchi, S. E., Kosiborod, M., Leiter, L. A., Lipska, K. J., Newman, J. D., et al. (2020) · Circulation · doi:10.1161/cir.0000000000000766 · Cited by 304 · see citing works
Development and Validation of a Short Version of the Seattle Angina Questionnaire
Chan, P. S., Jones, P. G., Arnold, S. A., & Spertus, J. (2014) · Circulation. Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.114.000967 · Cited by 287 · see citing works
2014 ESC/EACTS Guidelines on myocardial revascularization
Windecker, S., Kolh, P. H., Alfonso, F., Collet, J., Cremer, J., Falk, V., Filippatos, G. S., Hamm, C. W., Head, S. J., Jüni, P., et al. (2015) · EuroIntervention · doi:10.4244/eijy14m09_01 · Cited by 332 · see citing works
Treatment of Higher-Risk Patients With an Indication for Revascularization
Kirtane, A., Doshi, D., Leon, M., Lasala, J., Ohman, E., O'Neill, W., Shroff, A., Cohen, M. G., Palacios, I., Beohar, N., et al. (2016) · Circulation · doi:10.1161/circulationaha.116.022061 · Cited by 219 · see citing works
The Lancet Commission on rethinking coronary artery disease: moving from ischaemia to atheroma
Zaman, S. J., Wasfy, J. H., Kapil, V., Ziaeian, B., Parsonage, W. A., Sriswasdi, S., Chico, T., Capodanno, D., Colleran, R., Sutton, N. R., et al. (2025) · The Lancet · doi:10.1016/s0140-6736(25)00055-8 · Cited by 228 · see citing works
Thomas, M. B., Jones, P. G., Arnold, S. V., & Spertus, J. A. (2021) · JAMA Cardiology · doi:10.1001/jamacardio.2020.7478 · Cited by 166 · see citing works
2014 ESC/EACTS Guidelines on myocardial revascularization
Windecker, S., Kolh, P. H., Alfonso, F., Collet, J., Cremer, J., Falk, V., Filippatos, G. S., Hamm, C. W., Head, S. J., Jüni, P., et al. (2014) · Kardiologia Polska · doi:10.5603/kp.2014.0224 · Cited by 416 · see citing works
[2018 ESC/EACTS Guidelines on myocardial revascularization].
Neumann, F., Sousa-Uva, M., Ahlsson, A., Alfonso, F., Banning, A., Benedetto, U., Byrne, R., Collet, J., Falk, V., Head, S., et al. (2018) · Kardiologia polska · doi:10.5603/kp.2018.0228 · Cited by 108 · see citing works
Quality of Life After Surgery or DES in Patients With 3-Vessel or Left Main Disease
Abdallah, M. S., Wang, K., Magnuson, E. A., Osnabrugge, R. L., Kappetein, A. P., Morice, M.-C., Mohr, F. A., Serruys, P. W., & Cohen, D. J. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.02.031 · Cited by 82 · see citing works
“Several previous studies compared health status after CABG versus PCI using a variety of different techniques including balloon angioplasty (BARI [Bypass Angioplasty Revascularization Investigation], RITA [Randomized Intervention Treatment of Angina], GABI [German Angioplasty Bypass Surgery Investigation], and CABRI […”
MethodResultSelf-citationOptimal Blood Pressure During Cardiopulmonary Bypass Defined By Cerebral Autoregulation Monitoring
Hori, D., Nomura, Y., Ono, M., Joshi, B. L., Mandal, K., Cameron, D., Kocherginsky, M., & Hogue, C. (2017) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2017.04.091 · Cited by 80
Quality-of-Life After Everolimus-Eluting Stents or Bypass Surgery for Left-Main Disease
Baron, S. J., Chinnakondepalli, K., Magnuson, E. A., Kandzari, D. E., Puskas, J. D., Ben‐Yehuda, O., van Es, G., Taggart, D. P., Morice, M., Lembo, N., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.10.036 · Cited by 95 · see citing works
Guo, M., Wells, G., Glineur, D., Fortier, J. H., Davierwala, P., Kikuchi, K., Lemma, M., Mishra, Y., McGinn, J., Ramchandani, M., et al. (2019) · Contemporary Clinical Trials · doi:10.1016/j.cct.2019.01.006 · Cited by 66 · see citing works
Trajectories of Health-Related Quality of Life in Coronary Artery Disease
Sajobi, T. T., Wang, M., Awosoga, O., Santana, M., Southern, D., Liang, Z., Galbraith, D., Wilton, S., Quan, H., Graham, M., et al. (2018) · Circulation. Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.117.003661 · Cited by 66 · see citing works
Surgical Unroofing of Hemodynamically Significant Left Anterior Descending Myocardial Bridges.
Boyd, J., Pargaonkar, V. S., Scoville, D. H., Rogers, I. S., Kimura, T., Tanaka, S., Yamada, R., Fischbein, M., Tremmel, J., Mitchell, R., et al. (2017) · Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2016.08.035 · Cited by 63 · see citing works
Assessing quality-of-life outcomes in cardiovascular clinical research
Mark, D. (2016) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2016.10 · Cited by 58 · see citing works
Alexander, K. P., Weisz, G., Prather, K. O., James, S., Mark, D. B., Anstrom, K., Davidson-Ray, L., Witkowski, A., Mulkay, A. J., Osmukhina, A., et al. (2016) · Circulation · doi:10.1161/circulationaha.115.019768 · Cited by 55 · see citing works
Mortality After Repeat Revascularization Following PCI or CABG for Left Main Disease
Giustino, G., Serruys, P. W. J. C., Sabik, J. F., Mehran, R., Maehara, A., Puskas, J. D., Simonton, C. A., Lembo, N., Kandzari, D. E., Morice, M., et al. (2020) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2019.09.019 · Cited by 90 · see citing works
“Also, despite the slightly greater rates of revascularization in the PCI arm in EXCEL, the overall health status, quality of life, and freedom from angina at 3 years after PCI and CABG were not significantly different in this trial (25), in contrast to prior reports (26,27).”
ResultBen-Yehuda, O., Kazi, D. S., Bonafede, M., Wade, S. W., Machacz, S., Stephens, L., Hlatky, M., & Hernandez, J. (2016) · Catheterization and cardiovascular interventions · doi:10.1002/ccd.26365 · Cited by 53 · see citing works
Şen, H., Lam, M.-K., Löwik, M., Danse, P., Jessurun, G., van Houwelingen, K. V., Anthonio, R., Gin, R., Hautvast, R., Louwerenburg, J. W., et al. (2015) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2015.01.033 · Cited by 51 · see citing works
“0% of patients to be free from angina at 1- and 2-year follow-up after PCI with firstgeneration sirolimus-eluting stents (27), but this excellent result may be partly attributed to the general lower incidence of angina in diabetic patients.”
BackgroundChan, W., Ivanov, J., Ko, D. T., Fremes, S., Rao, V., Jolly, S., Cantor, W., Lavi, S., Overgaard, C., Ruel, M., et al. (2014) · Circulation. Cardiovascular Interventions · doi:10.1161/circinterventions.114.001973 · Cited by 51 · see citing works
Myocardial Revascularization Trials: Beyond the Printed Word
Ruel, M., Falk, V., Farkouh, M., Freemantle, N., Gaudino, M., Glineur, D., Cameron, D., & Taggart, D. (2018) · Circulation · doi:10.1161/circulationaha.118.035970 · Cited by 48 · see citing works
Tajabadi, M., Orimi, H. G., Ramzgouyan, M. R., Nemati, A., Deravi, N., Beheshtizadeh, N., & Azami, M. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112584 · Cited by 43 · see citing works
Patient-Reported Outcomes in Cardiovascular Trials
Creber, R. M. M., Spadaccio, C., Dimagli, A., Myers, A. C., Taylor, B., & Fremes, S. (2021) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2021.04.006 · Cited by 38 · see citing works
Krzych, Ł., Lach, M., Joniec, M., Cisowski, M., & Bochenek, A. (2018) · Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · doi:10.5114/kitp.2018.76480 · Cited by 36 · see citing works
Percutaneous coronary invervention versus coronary artery bypass grafting: a meta-analysis.
Smit, Y., Vlayen, J., Koppenaal, H., Eefting, F., Kappetein, A., & Mariani, M. (2015) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2014.10.112 · Cited by 36 · see citing works
Kulik, A. (2017) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000458 · Cited by 34 · see citing works
Fezzi, S., Ding, D., Mahfoud, F., Huang, J., Lansky, A., Tu, S.-X., & Wijns, W. (2024) · Nature Reviews Cardiology · doi:10.1038/s41569-024-01014-0 · Cited by 33 · see citing works
Invasive Coronary Physiology After Stent Implantation: Another Step Toward Precision Medicine.
Biscaglia, S., Uretsky, B., Barbato, E., Collet, C., Onuma, Y., Jeremias, A., Tebaldi, M., Hakeem, A., Kogame, N., Sonck, J., et al. (2021) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2020.10.055 · Cited by 32
Nishi, T., Piróth, Z., de Bruyne, B., Jagic, N., Möbius-Winkler, S., Kobayashi, Y., Dérimay, F., Fournier, S., Barbato, E., Tonino, P., et al. (2018) · Circulation · doi:10.1161/circulationaha.118.035263 · Cited by 31 · see citing works
Damluji, A. A., Nanna, M. G., Mason, P., Lowenstern, A. M., Orkaby, A. R., Washam, J. B., Kolkailah, A. A., Beckie, T. M., Dangas, G., & Lawton, J. S. (2025) · Circulation · doi:10.1161/cir.0000000000001387 · Cited by 29 · see citing works
Qintar, M., Grantham, J., Sapontis, J., Gosch, K., Lombardi, W., Karmpaliotis, D., Moses, J. W., Salisbury, A. C., Cohen, D. J., Spertus, J., et al. (2017) · Circulation. Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.117.003665 · Cited by 28 · see citing works
Mark, D. B., Spertus, J. A., Bigelow, R., Anderson, S., Daniels, M. R., Anstrom, K. J., Baloch, K. N., Cohen, D. J., Held, C., Goodman, S. G., et al. (2022) · Circulation · doi:10.1161/circulationaha.121.057363 · Cited by 32 · see citing works
Individualizing Revascularization Strategy for Diabetic Patients With Multivessel Coronary Disease
Qintar, M., Humphries, K. H., Park, J. E., Arnold, S. V., Tang, Y., Jones, P. G., Salisbury, A. C., Kureshi, F., Farkouh, M. E., Fuster, V., et al. (2019) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2019.07.083 · Cited by 30 · see citing works
Fatima, K., Yousuf-Ul-Islam, M., Ansari, M., Bawany, F., Khan, M. S., Khetpal, A., Khetpal, N., Lashari, M. N., Arshad, M. H., Amir, R. B., et al. (2016) · Cardiology Research and Practice · doi:10.1155/2016/7842514 · Cited by 24 · see citing works
“The remaining four studies [8, 14, 15, 17] found QOL to be the same in both groups.”
BackgroundPhysiological Assessment of Coronary Lesions in 2020
Chowdhury, M., & Osborn, E. (2020) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-020-0803-7 · Cited by 21 · see citing works
Li, Y., Dong, R., Hua, K., Liu, T.-S., Zhou, S., Zhou, N., & Zhang, H.-J. (2017) · Chinese Medical Journal · doi:10.4103/0366-6999.220305 · Cited by 21 · see citing works
“[21] CABG surgery provided better intermediate‐term health status and quality of life than PCI using DES.[22] Another amazing finding was the less aggressive dual anti‐platelet treatment in CABG patients on account of only 59.”
BackgroundQuality of Life Changes in Acute Coronary Syndromes Patients: A Systematic Review and Meta-Analysis
Kaambwa, B., Gesesew, H., Horsfall, M., & Chew, D. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17186889 · Cited by 20 · see citing works
“[41] Low risk Unclear risk Low risk Low risk Low risk Low risk Low risk Azmi et al.”
BackgroundInfluentialHolmes, D., & Taggart, D. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw044 · Cited by 20 · see citing works
Putzu, A., Gallo, M., Martino, E. A., Ferrari, E., Pedrazzini, G., Moccetti, T., & Cassina, T. (2017) · International Journal of Cardiology · doi:10.1016/j.ijcard.2017.04.015 · Cited by 19 · see citing works
Prognostic Value of Postpercutaneous Coronary Intervention Murray-Law-Based Quantitative Flow Ratio
Ding, D., Zhang, J.-L., Wu, P., Wang, Z.-Q., Shi, H.-P., Yu, W., Hu, X.-Y., Kang, J., Hahn, J., Nam, C., et al. (2025) · JACC: Asia · doi:10.1016/j.jacasi.2024.10.019 · Cited by 18
Maznyczka, A. M., Howard, J., Banning, A., & Gershlick, A. (2016) · Open Heart · doi:10.1136/openhrt-2015-000322 · Cited by 18
Brogan, R., Malkin, C., Batin, P., Simms, A., Mclenachan, J., & Gale, C. (2014) · World Journal of Cardiology · doi:10.4330/wjc.v6.i8.865 · Cited by 18
Ferket, B. S., Ailawadi, G., Gelijns, A., Acker, M. A., Hohmann, S. F., Chang, H. L., Bouchard, D., Meltzer, D., Michler, R. E., Moquete, E. G., et al. (2018) · Circulation. Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.117.004466 · Cited by 17 · see citing works
Arnold, S., Spertus, J., Lipska, K., Tang, F., Goyal, A., Mcguire, D. K., Cresci, S., Maddox, T., & Kosiborod, M. (2014) · European Journal of Preventive Cardiology · doi:10.1177/2047487314533622 · Cited by 17 · see citing works
“3 points at 2 years) compared with drug-eluting stents.(30) While we did adjust for revascularization type in our multivariable analysis, this may be one potential target to narrow the gap in angina burden between patients with and without DM.”
Guía de práctica clínica de la ESC sobre revascularización miocárdica, 2014
Windecker, S., Kolh, P., Alfonso, F., Collet, J.-P., Crémer, J., Falk, V., Filippatos, G., Hamm, C. W., Head, S. J., Jüni, P., et al. (2015) · doi:10.1016/j.recesp.2014.12.007 · Cited by 17
Quality of Life After Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting
Dimagli, A., Spadaccio, C., Myers, A. C., Demetres, M., Rademaker-Havinga, T., Stone, G., Spertus, J., Redfors, B., Fremes, S. E., Gaudino, M., et al. (2023) · Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease · doi:10.1161/jaha.123.030069 · Cited by 16 · see citing works
Jia, S., Zhang, C., Jiang, L., Xu, L.-J., Tian, J., Zhao, X.-Y., Feng, X.-X., Wang, D., Zhang, Y., Sun, K., et al. (2020) · Circulation Journal · doi:10.1253/circj.cj-20-0300 · Cited by 16 · see citing works
Factors Affecting In-stent Restenosis in Patients Undergoing Percutaneous Coronary Angioplasty
Sajadian, M., Alizadeh, L., Ganjifard, M., Mardani, A., Ansari, M., & Falsoleiman, H. (2018) · Galen medical journal · doi:10.22086/gmj.v0i0.961 · Cited by 15
“3 and 41%; for example, it is estimated that annually about 150 thousand people in America are suffering from this complication [1-4].”
BackgroundDurability of Minimally Invasive Coronary Artery Bypass Grafting.
Guo, M., Vo, T., Horsthuis, K., Rahmouni, K., Chong, A., Glineur, D., & Ruel, M. (2021) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2021.07.040 · Cited by 14
Diabetes mellitus type 2 in adults
Dedov, I. I., Shestakova, M. V., Mayorov, A. Y., Шамхалова, М. Ш., Sukhareva, O. Y., Galstyan, G. R., Tokmakova, A. Y., Nikonova, T. V., Surkova, E. V., Кононенко, И. В., et al. (2020) · Diabetes Mellitus · doi:10.14341/dm12507 · Cited by 58 · see citing works
Chen, G. M., Pather, S. R., & Delisser, H. (2019) · JAMA Network Open · doi:10.1001/jamanetworkopen.2019.1083 · Cited by 14 · see citing works
Wang, J., Yang, Z.-G., Guo, Y.-K., Jiang, Y., Yan, W.-F., Qian, W.-L., Fang, H., Min, C.-Y., & Li, Y. (2023) · Cardiovascular Diabetology · doi:10.1186/s12933-023-01873-w · Cited by 13
“Current therapies for diabetes patients with multi-vessel OCAD include percutaneous coronary intervention and coronary artery bypass graft (CABG), both of which have improved the prognosis among those patients [37, 38].”
BackgroundHuang, Y.-X., Xu, Z.-M., Zhao, L., Cao, Y., Chen, Y., Qiu, Y.-G., Liu, Y.-M., Zhang, P.-Y., He, J.-C., & Li, T.-C. (2022) · World Journal of Clinical Cases · doi:10.12998/wjcc.v10.i16.5266 · Cited by 13 · see citing works
Giustino, G., & Dangas, G. (2015) · Progress in cardiovascular diseases · doi:10.1016/j.pcad.2015.08.005 · Cited by 13 · see citing works
“QoL substudy evaluated the health status of patients enrolled in the FREEDOM cohort at baseline, 1, 6 and 12 months and annually thereafter by means of the Seattle Angina Questionnaire (SAQ) and the Rose Dyspnea Scale (RDS).(29) The SAQ is a validated QoL measurement tool designed to evaluate CAD-related health status…”
MethodYang, L.-X., Zhou, Y.-J., Wang, Z.-J., Li, Y.-P., & Chai, M. (2014) · Journal of Geriatric Cardiology · doi:10.11909/j.issn.1671-5411.2014.03.003 · Cited by 12 · see citing works
External Validation of the FREEDOM Score for Individualized Decision Making Between CABG and PCI.
Takahashi, K., Serruys, P., Fuster, V., Farkouh, M., Spertus, J., Cohen, D., Park, S.-J., Park, D.-W., Ahn, J.-M., Onuma, Y., et al. (2022) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2022.01.049 · Cited by 11 · see citing works
Ferket, B., Thourani, V., Voisine, P., Hohmann, S., Chang, H. L., Smith, P. K., Michler, R., Ailawadi, G., Perrault, L., Miller, M. A., et al. (2019) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2019.06.040 · Cited by 11
Stenvall, H., Tierala, I., Räsänen, P., Laine, M., Sintonen, H., & Roine, R. (2017) · European Heart Journal - Quality of Care and Clinical Outcomes · doi:10.1093/ehjqcco/qcw024 · Cited by 11 · see citing works
Singh, S., Sinha, V., Singh, S., Kapoor, L., Praharaj, S., Tikka, S., & Singh, L. (2020) · The Indian journal of medical research · doi:10.4103/ijmr.ijmr_1310_18 · Cited by 9 · see citing works
Won, M. H. (2019) · Korean Journal of Adult Nursing · doi:10.7475/kjan.2019.31.6.691 · Cited by 10 · see citing works
“이는 관상동맥질환자의 건강 관련 삶의 질은 연령, 성별 및 질병중증도와 같은 개인적 특성에 영 향을 받는다고 보고한 선행연구[6,11,12]와 퇴원 후 시간의 경”
Diabetes and multivessel disease
Godoy, L. C., Rao, V. A., & Farkouh, M. E. (2018) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000550 · Cited by 10 · see citing works
McGrath, B., Norris, C., Hardwicke-Brown, E., Welsh, R., & Bainey, K. (2017) · European Heart Journal - Quality of Care and Clinical Outcomes · doi:10.1093/ehjqcco/qcw055 · Cited by 9 · see citing works
Mahdavi, M., Abbasi, I., & Mohammadi, N. (2015) · doi:10.18869/acadpub.hms.21.2.67 · Cited by 9
Nonsternotomy multivessel coronary artery bypass grafting: A key development in cardiac surgery
Ruel, M. (2021) · JTCVS Techniques · doi:10.1016/j.xjtc.2021.09.033 · Cited by 8 · see citing works
Residual angina in female patients after coronary revascularization.
Vogel, B., Goel, R., Kunadian, V., Kalkman, D., Chieffo, A., Appelman, Y., & Mehran, R. (2019) · International Journal of Cardiology · doi:10.1016/j.ijcard.2019.01.043 · Cited by 8 · see citing works
On-Pump Coronary Artery Bypass Graft: The State of the Art.
Cuminetti, G., Bonadei, I., Vizzardi, E., Sciatti, E., & Lorusso, R. (2019) · Reviews on recent clinical trials · doi:10.2174/1574887114666190301142114 · Cited by 8 · see citing works
Castelvecchio, S., Menicanti, L., Garatti, A., Tramarin, R., Volpe, M., & Parolari, A. (2016) · Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2016.02.081 · Cited by 8 · see citing works
Hybrid approach for coronary artery revascularization: where do we stand?
Toeg, H., Al-Atassi, T., Labinaz, M., May, M. L. L., & Ruel, M. (2014) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000112 · Cited by 8 · see citing works
“Recent findings Current forms of HCAR include off-pump mini-sternotomy or on-pump full sternotomy CABG [left internal mammary artery (LIMA)-to-left anterior descending artery(LAD) CABG followed by drug-eluting stents (DES) to non-LAD territories], robotic-assisted off-pump HCAR (robotic LIMA-to-LAD CABG and DES to non…”
BackgroundMethodInfluentialCoronary Microvascular Dysfunction
Carli, M. F. D. (2025) · Heart Failure Clinics · doi:10.1016/j.hfc.2025.01.002 · Cited by 7 · see citing works
Rahman, A., Haider, R., Shirin, H., Sobhan, A., & Huq, K. E. (2024) · Cureus · doi:10.7759/cureus.52645 · Cited by 7
“A study by Abdallah et al. observed that patients who underwent CABG had better QoL between six months and two years compared to those who underwent PCI; however, these differences were not found significant [17].”
ResultFan, Q., Liu, J., Xu, Y., Ni, R., Xi, R., Wang, F., Hu, J., Sun, H.-Y., Yang, Z.-K., Zhou, M., et al. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.675722 · Cited by 7 · see citing works
Kok, M. M., & von Birgelen, C. (2020) · EuroIntervention · doi:10.4244/eijv15i14a221 · Cited by 7
Bruckel, J., Wagle, N. W., O'Brien, C., Elias, J. S., McKenna, S., Meyers, P., Fifer, M., Pomerantsev, E., & Yeh, R. (2015) · Critical Pathways in Cardiology · doi:10.1097/hpc.0000000000000058 · Cited by 7 · see citing works
Krause, T. T., Afzal, S., Gjata, A., Lindner, M., Saad, L., Steinbach, M., Zayat, R., Haneya, A., Werner, N., & Leick, J. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1451229 · Cited by 6 · see citing works
Effects of percutaneous coronary intervention on dyspnea in stable coronary artery disease
Wester, M., Koll, F., Luedde, M., Langer, C., Resch, M., Luchner, A., Müller, K., Zeman, F., Koller, M., Maier, L., et al. (2022) · Clinical Research in Cardiology · doi:10.1007/s00392-022-02107-x · Cited by 6
Ono, M., Serruys, P., Kawashima, H., Lunardi, M., Wang, R.-T., Hara, H., Gao, C., Garg, S., O'Leary, N., Wykrzykowska, J., et al. (2022) · European Heart Journal - Quality of Care and Clinical Outcomes · doi:10.1093/ehjqcco/qcac052 · Cited by 6 · see citing works
Dawson, L. P., Quinn, S. J., Tong, D., Boyle, A. J., Hamilton-Craig, C. R., Adams, H. S. L., & Layland, J. J. (2022) · Cardiovascular revascularization medicine · doi:10.1016/j.carrev.2022.06.017 · Cited by 7 · see citing works
Gao, K., Li, B.-L., Zhang, M., Rong, J., Yang, L., Fan, L., Liang, Q., Wu, W., Feng, Z., Yang, W.-W., et al. (2021) · Angiology · doi:10.1177/0003319721998575 · Cited by 6
“The SAQ, which quantifies 5 domains to measure the impact of angina on patient health status, has been shown to be effective, reproducible, and sensitive to changes in clinical symptoms.(34,35) Safley et al reported that all SAQ scores improved in patients with CTO and non-CTO patients after PCI, and there were no dif…”
MethodLong-term survival in patients who had CABG with or without prior coronary artery stenting
Rai, P., Taylor, R., & Bittar, M. N. (2020) · Open Heart · doi:10.1136/openhrt-2019-001160 · Cited by 6
Ruel, M., Sun, L. Y., & Gaudino, M. (2020) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2019.04.088 · Cited by 6 · see citing works
Kumar, R., Hote, M., Sharma, G., Thakur, B., & Airan, B. (2017) · doi:10.11648/j.ijcts.20170305.14 · Cited by 6
“In 1954, Murray and colleagues were considering a direct surgical approach to CAD and reported experimental studies of anastomosing the ITA to a coronary artery.”
BackgroundInfluentialLawton, R., Seed, P. T., Kordowicz, M., Schofield, P., Tylee, A. T., & Ashworth, M. J. (2014) · British Journal of General Practice · doi:10.3399/bjgp14x680137 · Cited by 5 · see citing works
Operative Techniques in Coronary Artery Bypass Surgery: An Illustrated Guide to Personalized Therapy
Albert, A., Assmann, A., Assmann, A., Aubin, H., & Lichtenberg, A. (2021) · doi:10.1007/978-3-030-48497-2 · Cited by 6
“Totally arterial revascularization with BITA can be conducted in aortic no-touch technique to revascularize all possible targets on the anterior, lateral and posterior walls, as far as the RITA is long enough [45].”
MethodInfluence of Pullback Pressure Gradient on Residual Angina at One Year
Mizukami, T., Ikeda, K., Munhoz, D., Sakai, K., Sonck, J., Matsuo, H., Shinke, T., Ando, H., Ko, B., Biscaglia, S., et al. (2026) · Circulation. Cardiovascular Interventions · doi:10.1161/circinterventions.125.015851 · Cited by 5
Minimally Invasive CABG Is The Future: Pro.
Ruel, M., & Halkos, M. E. (2024) · Seminars in Thoracic and Cardiovascular Surgery · doi:10.1053/j.semtcvs.2024.09.003 · Cited by 5
Quality of Life After Fractional Flow Reserve–Guided PCI Compared With Coronary Bypass Surgery
Fearon, W., Zimmermann, F., Ding, V., Zelis, J., Piróth, Z., Davidavičius, G., Mansour, S., Kharbanda, R., Östlund-Papadogeorgos, N., Oldroyd, K., et al. (2022) · Circulation · doi:10.1161/circulationaha.122.060049 · Cited by 5 · see citing works
Nielsen, S. N., Rasmussen, T. B., Lassen, J., Berg, S., Thrysoee, L., Møller, J., Jensen, L., Thuesen, A. L., Christensen, A. V., Ekholm, O., et al. (2020) · Quality of Life Research · doi:10.1007/s11136-020-02573-8 · Cited by 5 · see citing works
Zheng, X., Dreyer, R., Curtis, J., Liu, S.-L., Xu, X., Bai, X., Li, X., Zhang, H.-B., Wang, S.-M., Masoudi, F., et al. (2020) · Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease · doi:10.1161/jaha.119.014421 · Cited by 5 · see citing works
Grundeken, M., White, R. M., Hernandez, J., Dudek, D., Cequier, Á., Haude, M., van Boven, A. J., Piek, J., Helqvist, S., Sabaté, M., et al. (2016) · European Heart Journal - Quality of Care and Clinical Outcomes · doi:10.1093/ehjqcco/qcv022 · Cited by 5 · see citing works
Schuering, C. L., Zwaans, V. I. T., Huang, A., Köhler-Seuster, M., von Mackensen, J. K. R., Iske, J., Stein, J., Kaemmel, J., Heck, R., Starck, C. T., et al. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1650138 · Cited by 4
Huded, C. P., Spertus, J., Jones, P. G., O'Brien, S. M., Mark, D. B., Bangalore, S., Stone, G., Williams, D., White, H., Boden, W. E., et al. (2025) · Circulation · doi:10.1161/circulationaha.125.073591 · Cited by 4 · see citing works
Coronary Artery Bypass Grafting: A Review of Short- and Long-Term Outcomes
Adeyemi, A. M., Berman, L., Staroselsky, M., Cordero, D., Hai, O. Y., Makaryus, A., & Zeltser, R. (2025) · International Journal of Angiology · doi:10.1055/a-2655-2479 · Cited by 4
Efficacy and risks of drug-coated balloon treatment for coronary artery disease: A meta-analysis
Bai, X., Shen, C., Zhang, W.-Z., Yu, T., & Jiang, J. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e22224 · Cited by 4
“During balloon inflation, this drug is transferred to the intimal layer of the vessel wall, facilitating rapid delivery of lipophilic medication and inhibiting smooth muscle cell proliferation [8,9].”
Background
- Authors
- Abdallah, M. S.
- Affiliations
- Saint Luke's Hospital (US)
- Corresponding author
- Abdallah, Mouin S.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2013-10-16
- Volume
- 310
- Issue
- 15
- Pages
- 1581
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- PMC
- PMC4370776
- OpenAlex
- W2025139632
- Cited by
- 169
- References
- 43
- Citations by year
- 2026: 8 · 2025: 14 · 2024: 6 · 2023: 9 · 2022: 16 · 2021: 15 · 2020: 15 · 2019: 12 · 2018: 11 · 2017: 17 · 2016: 18 · 2015: 14 · 2014: 13 · 2013: 1
- FWCI
- 15.13
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Heart, Lung, and Blood Institute (U01 01HL071988, R01HL092989, P50HL077113, U01HL071988, U01 01HL092989)
- Topics
- Health Sciences › Medicine › Surgery › Coronary Interventions and Diagnostics
- Health Sciences › Medicine › Surgery › Cardiac and Coronary Surgery Techniques
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Keywords
- coronary artery bypass grafting, percutaneous coronary intervention, drug-eluting stents, diabetes mellitus, multivessel coronary artery disease, quality of life, Seattle Angina Questionnaire, angina frequency, physical limitations, health status, FREEDOM trial, revascularization, patient-reported outcomes, stroke risk, myocardial infarction, mortality
- MeSH terms
- Aged, Angina Pectoris, Coronary Artery Bypass, Coronary Artery Disease, Diabetes Mellitus, Female, Health Status, Humans, Male, Middle Aged, Quality of Life, Treatment Outcome, Diabetes Complications, Drug-Eluting Stents, Percutaneous Coronary Intervention
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
