Cited by 776Atrial Fibrillation Management and OutcomesCardiac Health and Mental HealthHeart Failure Treatment and Management

The DOI matches its Crossref record; 51 of the 52 references it cites were found in a registry or an index.

Effect of Weight Reduction and Cardiometabolic Risk Factor Management on Symptom Burden and Severity in Patients With Atrial Fibrillation: A Randomized Clinical Trial

Abed, Hany S., Wittert, Gary A., Leong, Darryl P., Shirazi, Masoumeh G., Bahrami, Bobak, Middeldorp, Melissa E., Lorimer, Michelle F., Lau, Dennis H., Antic, Nicholas A., Brooks, Anthony G., Abhayaratna, Walter P., Kalman, Jonathan M., Sanders, Prashanthan·2013·JAMA

DOI 10.1001/jama.2013.280521

Open this paper in CoChat — free account

Abstract

IMPORTANCE: Obesity is a risk factor for atrial fibrillation. Whether weight reduction and cardiometabolic risk factor management can reduce the burden of atrial fibrillation is not known. OBJECTIVE: To determine the effect of weight reduction and management of cardiometabolic risk factors on atrial fibrillation burden and cardiac structure. DESIGN, SETTING, AND PATIENTS: Single-center, partially blinded, randomized controlled study conducted between June 2010 and December 2011 in Adelaide, Australia, among overweight and obese ambulatory patients (N = 150) with symptomatic atrial fibrillation. Patients underwent a median of 15 months of follow-up. INTERVENTIONS: Patients were randomized to weight management (intervention) or general lifestyle advice (control). Both groups underwent intensive management of cardiometabolic risk factors. MAIN OUTCOMES AND MEASURES: The primary outcomes were Atrial Fibrillation Severity Scale scores: symptom burden and symptom severity. Scores were measured every 3 months from baseline to 15 months. Secondary outcomes performed at baseline and 12 months were total atrial fibrillation episodes and cumulative duration measured by 7-day Holter, echocardiographic left atrial area, and interventricular septal thickness. RESULTS: Of 248 patients screened, 150 were randomized (75 per group) and underwent follow-up. The intervention group showed a significantly greater reduction, compared with the control group, in weight (14.3 and 3.6 kg, respectively; P < .001) and in atrial fibrillation symptom burden scores (11.8 and 2.6 points, P < .001), symptom severity scores (8.4 and 1.7 points, P < .001), number of episodes (2.5 and no change, P = .01), and cumulative duration (692-minute decline and 419-minute increase, P = .002). Additionally, there was a reduction in interventricular septal thickness in the intervention and control groups (1.1 and 0.6 mm, P = .02) and left atrial area (3.5 and 1.9 cm2, P = .02). CONCLUSIONS AND RELEVANCE: In this study, weight reduction with intensive risk factor management resulted in a reduction in atrial fibrillation symptom burden and severity and in beneficial cardiac remodeling. These findings support therapy directed at weight and risk factors in the management of atrial fibrillation. TRIAL REGISTRATION: anzctr.org.au Identifier: ACTRN12610000497000.

Integrity signals

Registry

Crossref · 10.1001/jama.2013.280521

Cites

51 of 51 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)
Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944
Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
Grundy, S. M., Becker, D. M., Clark, L. T., Cooper, R., Denke, M. A., Howard, J. L., Hunninghake, D. B., Illingworth, D. R., Luepker, R. V., McBride, P. E., et al. (2002) · Civil War Book Review · Cited by 12,198
Recommendations for Chamber Quantification: A Report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, Developed in Conjunction with the European Association of Echocardiography, a Branch of the European Society of Cardiology
Lang, R. M., Bierig, M., Devereux, R. B., Flachskampf, F. A., Foster, E., Pellikka, P. A., Picard, M. H., Roman, M. J., Seward, J., Shanewise, J. S., et al. (2005) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2005.10.005 · Cited by 11,318
Sleep–Related Breathing Disorders in Adults: Recommendations for Syndrome Definition and Measurement Techniques in Clinical Research
(1999) · Sleep · doi:10.1093/sleep/22.5.667 · Cited by 5,147
Impact of Atrial Fibrillation on the Risk of Death: The Framingham Heart Study
Benjamin, E. J., Wolf, P. A., D’Agostino, R. B., Silbershatz, H., Kannel, W. B., & Levy, D. (1998) · Circulation · doi:10.1161/01.cir.98.10.946 · Cited by 4,575
Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force.
McNicholas, W. T., Strohl, K. P., White, D. P., Levy, P. A., Schmidt, W., Wheatley, J. R., Redline, S. S., Carley, D. W., Buysse, D. J., Young, T. B., et al. (1999) · PubMed · Cited by 3,665
Independent Risk Factors for Atrial Fibrillation in a Population-Based Cohort: The Framingham Heart Study
Benjamin, E. J. (1994) · JAMA · doi:10.1001/jama.1994.03510350050036 · Cited by 2,613
Secular Trends in Incidence of Atrial Fibrillation in Olmsted County, Minnesota, 1980 to 2000, and Implications on the Projections for Future Prevalence
Miyasaka, Y., Barnes, M. E., Gersh, B. J., Cha, S. S., Bailey, K. R., Abhayaratna, W. P., Seward, J. B., & Tsang, T. S. M. (2006) · Circulation · doi:10.1161/circulationaha.105.595140 · Cited by 2,564
Elevated C-reactive protein levels in overweight and obese adults
Visser, M. (1999) · JAMA · doi:10.1001/jama.282.22.2131 · Cited by 2,494
Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: population-based estimates 11Reprints are not available.
Kannel, W. B., Wolf, P. A., Benjamin, E. J., & Levy, D. (1998) · The American Journal of Cardiology · doi:10.1016/s0002-9149(98)00583-9 · Cited by 2,033

Show all 52 references

Sorted by citations

Items 201–300 of 775

Disease–treatment interactions in the management of patients with obesity and diabetes who have atrial fibrillation: the potential mediating influence of epicardial adipose tissue
Packer, M. (2019) · Cardiovascular Diabetology · doi:10.1186/s12933-019-0927-9 · Cited by 56
Racial differences and similarities in atrial fibrillation epidemiology and risk factors in UK Biobank and Korean NHIS-HEALS cohort studies
Kim, M.-H., Yang, P., Kim, D., Jang, E., Yu, H. T., Kim, T.-H., Sung, J., Pak, H., Lee, M., Lip, G. Y. H., et al. (2025) · Heart Rhythm · doi:10.1016/j.hrthm.2025.02.013 · Cited by 51
Metabolic syndrome, atrial fibrillation, and stroke: Tackling an emerging epidemic
Hajhosseiny, R., Matthews, G. D. K., & Lip, G. Y. H. (2015) · Heart Rhythm · doi:10.1016/j.hrthm.2015.06.038 · Cited by 53
Molecular mechanisms of atrial fibrosis: implications for the clinic
Thanigaimani, S., Lau, D. H., Agbaedeng, T. A., Elliott, A. D., Mahajan, R., & Sanders, P. (2017) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2017.1299005 · Cited by 50
Diagnosis‐to‐ablation time in atrial fibrillation: A modifiable factor relevant to clinical outcome
Bisbal, F., Alarcón, F., Ferrero‐de‐Loma‐Osorio, Á., González‐Ferrer, J. J., Alonso‐Martín, C., Pachón, M., Vallès, E., Cabanas‐Grandío, P., Sanchez, M., Benito, E., et al. (2019) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.14000 · Cited by 50
2021 ISHNE/ HRS/ EHRA/ APHRS collaborative statement on mHealth in Arrhythmia Management: Digital Medical Tools for Heart Rhythm Professionals
Varma, N., Cygankiewicz, I., Turakhia, M. P., Heidbüchel, H., Hu, Y., Chen, L. Y., Couderc, J., Cronin, E. M., Estep, J. D., Grieten, L., et al. (2021) · Annals of Noninvasive Electrocardiology · doi:10.1111/anec.12795 · Cited by 51
Genetic testing in early-onset atrial fibrillation
Kany, S., Jurgens, S. J., Rämö, J. T., Christophersen, I. E., Rienstra, M., Chung, M. K., OLESEN, M. S., Ackerman, M. J., McNally, E. M., Semsarian, C., et al. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae298 · Cited by 50
Management of atrial fibrillation in older adults
Parks, A. L., Frankel, D. S., Kim, D. H., Ko, D., Kramer, D. B., Lydston, M., Fang, M. C., & Shah, S. J. (2024) · BMJ · doi:10.1136/bmj-2023-076246 · Cited by 61
Associations of obesity and body fat distribution with incident atrial fibrillation in the biracial health aging and body composition cohort of older adults
Aronis, K. N., Wang, N., Phillips, C. L., Benjamin, E. J., Marcus, G. M., Newman, A. B., Rodondi, N., Satterfield, S., Harris, T. B., & Magnani, J. W. (2015) · American Heart Journal · doi:10.1016/j.ahj.2015.06.007 · Cited by 49
Impact of Body Mass Index on the Prognosis of Japanese Patients With Non-Valvular Atrial Fibrillation
Inoue, H., Kodani, E., Atarashi, H., Okumura, K., Yamashita, T., & Origasa, H. (2016) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2016.04.036 · Cited by 49
Atrial Remodelling in Heart Failure: Recent Developments and Relevance for Heart Failure with Preserved Ejection Fraction
Hohendanner, F., Messroghli, D., Bode, D., Blaschke, F., Parwani, A. S., Boldt, L., & Heinzel, F. R. (2018) · ESC Heart Failure · doi:10.1002/ehf2.12260 · Cited by 48
Inflammation and adiposity: new frontiers in atrial fibrillation
Vyas, V. S., Hunter, R. J., Longhi, M. P., & Finlay, M. (2020) · EP Europace · doi:10.1093/europace/euaa214 · Cited by 50
Cohort Profile: ChinaHEART (Health Evaluation And risk Reduction through nationwide Teamwork) Cohort
Wang, R., Yang, Y., Lu, J., Cui, J., Xu, W., Song, L., Wu, C., Zhang, X., Dai, H., Zhong, H., et al. (2023) · International Journal of Epidemiology · doi:10.1093/ije/dyad074 · Cited by 46
Atrial Cardiomyopathy in Atrial Fibrillation: Mechanistic Pathways and Emerging Treatment Concepts
Karakasis, P., Theofilis, P., Vlachakis, P. K., Ktenopoulos, N., Patoulias, D., Antoniadis, A. P., & Fragakis, N. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14093250 · Cited by 53
Clinical significance of nutritional status in patients with atrial fibrillation: An overview of current evidence
Anaszewicz, M., & Budzyński, J. (2016) · Journal of Cardiology · doi:10.1016/j.jjcc.2016.06.014 · Cited by 46
Non-Alcoholic Fatty Liver Disease and Cardiovascular Comorbidities: Pathophysiological Links, Diagnosis, and Therapeutic Management
Jichitu, A., BUNGAU, S. G., Stănescu, A. M. A., Vesa, C. M., Toma, M. M., Bustea, C., Iurciuc, S., Rus, M., Bacalbaşa, N., & Diaconu, C. C. (2021) · Diagnostics · doi:10.3390/diagnostics11040689 · Cited by 47
Chinese guidelines for the diagnosis and management of atrial fibrillation
Ma, C., Wu, S., Liu, S., & Han, Y. (2024) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.14920 · Cited by 48
Top 10 cardiovascular therapies and interventions for the next decade
Fuster, V. (2014) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2014.137 · Cited by 45
Impact of weight reduction on pericardial adipose tissue and cardiac structure in patients with atrial fibrillation.
Abed, H., Nelson, A., Richardson, J., Worthley, S., Vincent, A., Wittert, G., & Leong, D. (2015) · American Heart Journal · doi:10.1016/j.ahj.2015.02.008 · Cited by 49
Atrial Fibrillation and Heart Failure
Ariyaratnam, J., Lau, D. H., Sanders, P., & Kalman, J. M. (2021) · Cardiac Electrophysiology Clinics · doi:10.1016/j.ccep.2020.11.004 · Cited by 44
Obesity: The Perfect Storm for Heart Failure
Lembo, M., Strisciuglio, T., Fonderico, C., Mancusi, C., Izzo, R., Trimarco, V., Bellis, A., Barbato, E., Esposito, G., Morisco, C., et al. (2024) · ESC Heart Failure · doi:10.1002/ehf2.14641 · Cited by 51
The burden of proof: The current state of atrial fibrillation prevention and treatment trials
Zakeri, R., Wagoner, D. R. V., Calkins, H. G., Wong, T., Ross, H., Heist, E. K., Meyer, T. E., Kowey, P. R., Mentz, R. J., Cleland, J. G. F., et al. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.01.032 · Cited by 42
Sleep Apnea and Atrial Fibrillation
Linz, D., Nattel, S., Kalman, J. M., & Sanders, P. (2021) · Cardiac Electrophysiology Clinics · doi:10.1016/j.ccep.2020.10.003 · Cited by 45
The counterintuitive role of exercise in the prevention and cause of atrial fibrillation
Buckley, B. J. R., Lip, G. Y. H., & Thijssen, D. H. J. (2020) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00509.2020 · Cited by 43
Epicardial fat and atrial fibrillation: the perils of atrial failure
Poggi, A. L., Gaborit, B., Schindler, T. H., Liberale, L., Montecucco, F., & Carbone, F. (2022) · EP Europace · doi:10.1093/europace/euac015 · Cited by 41
Pericardial fat volume and incident atrial fibrillation in the Multi‐Ethnic Study of Atherosclerosis and Jackson Heart Study
Heckbert, S. R., Wiggins, K. L., Blackshear, C. T., Yang, Y., Ding, J., Liu, J., McKnight, B., Alonso, Á., Austin, T. R., Benjamin, E. J., et al. (2017) · Obesity · doi:10.1002/oby.21835 · Cited by 40
Atrial fibrillation prevention: an appraisal of current evidence
Boriani, G., & Proietti, M. (2017) · Heart · doi:10.1136/heartjnl-2017-311546 · Cited by 41
Relationship between epicardial adipose tissue volume and atrial fibrillation
Zhu, W., Zhang, H., Guo, L., & Hong, K. (2015) · Herz · doi:10.1007/s00059-015-4387-z · Cited by 40
Left Atrial Remodeling
Hoit, B. D. (2017) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.117.006036 · Cited by 40
Obesity as a risk factor for cardiac arrhythmias
Patel, K. H. K., Reddy, R. K., Sau, A., Sivanandarajah, P., Ardissino, M., & Ng, F. S. (2022) · BMJ Medicine · doi:10.1136/bmjmed-2022-000308 · Cited by 43
Atrial Fibrillation in Hypertrophic Cardiomyopathy
Vaidya, K., Semsarian, C., & Chan, K. H. (2017) · Heart Lung and Circulation · doi:10.1016/j.hlc.2017.05.116 · Cited by 40
Should We Perform Catheter Ablation for Asymptomatic Atrial Fibrillation?
Kalman, J. M., Sanders, P., Rosso, R., & Calkins, H. G. (2017) · Circulation · doi:10.1161/circulationaha.116.024926 · Cited by 42
Symptom severity is associated with cardiovascular outcome in patients with permanent atrial fibrillation in the RACE II study
Vermond, R. A., Crijns, H. J. G. M., Tijssen, J. G. P., ALINGS, A. M. W., van den Berg, M. P., Hillege, H. L., van Veldhuisen, D. J., Gelder, I. C. V., Rienstra, M., & for the RACE II investigators (2014) · EP Europace · doi:10.1093/europace/euu151 · Cited by 39
Research Priorities in the Secondary Prevention of Atrial Fibrillation: A National Heart, Lung, and Blood Institute Virtual Workshop Report
Benjamin, E. J., Al‐Khatib, S. M., Desvigne-Nickens, P. M., Alonso, Á., Djoussé, L., Forman, D. E., Gillis, A. M., Hendriks, J., Hills, M. T., Kirchhof, P. F., et al. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.121.021566 · Cited by 38
New Directions in Cardiac Arrhythmia Management: Present Challenges and Future Solutions
Nattel, S., Andrade, J. G., Macle, L., Rivard, L., Dyrda, K., Mondesert, B. A., & Khairy, P. (2014) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2014.09.027 · Cited by 37
HFpEF Is the Substrate for Stroke in Obesity and Diabetes Independent of Atrial Fibrillation
Packer, M. (2019) · JACC Heart Failure · doi:10.1016/j.jchf.2019.09.002 · Cited by 39
2021 ISHNE/HRS/EHRA/APHRS collaborative statement on mHealth in Arrhythmia Management: Digital Medical Tools for Heart Rhythm Professionals
Varma, N., Cygankiewicz, I., Turakhia, M. P., Heidbüchel, H., Hu, Y., Chen, L. Y., Couderc, J., Cronin, E. M., Estep, J. D., Grieten, L., et al. (2021) · Journal of Arrhythmia · doi:10.1002/joa3.12461 · Cited by 37
Sleep-Disordered Breathing and Cardiac Arrhythmias
Bitter, T., Fox, H., Gaddam, S., Horstkotte, D., & Oldenburg, O. (2015) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2015.04.022 · Cited by 38
Addressing Comorbidities in Heart Failure
Bavishi, A. A., & Patel, R. B. (2020) · Heart Failure Clinics · doi:10.1016/j.hfc.2020.06.005 · Cited by 40
Long-term influence of body mass index on cardiovascular events after atrial fibrillation ablation
Bunch, T. J., May, H. T., Bair, T. L., Crandall, B. G., Cutler, M. J., Jacobs, V., Mallender, C. D., Muhlestein, J. B., Osborn, J. S., Weiss, J. P., et al. (2016) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-016-0142-5 · Cited by 36
Inflammation as a Mediator of the Association Between Race and Atrial Fibrillation
Dewland, T. A., Vittinghoff, E., Harris, T. B., Magnani, J. W., Liu, Y., Hsu, F., Satterfield, S., Wassel, C. L., & Marcus, G. M. (2015) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2015.04.014 · Cited by 36
Risk factors for atrial fibrillation in type 2 diabetes: report from the Swedish National Diabetes Register (NDR)
Zethelius, B., Guðbjörnsdóttir, S., Eliasson, B., Eeg‐Olofsson, K., Svensson, A., & Cederholm, J. (2015) · Diabetologia · doi:10.1007/s00125-015-3666-9 · Cited by 38
Atrial Fibrillation Epidemic and Hospitalizations
Wong, C. X. J., Lau, D. H., & Sanders, P. (2014) · Circulation · doi:10.1161/circulationaha.114.010073 · Cited by 36
Current Evidence-Based Understanding of the Epidemiology, Prevention, and Treatment of Atrial Fibrillation
Rogers, P. A., Bernard, M. L., Madias, C. A., Thihalolipavan, S., Estes, N. A. M., & Morin, D. P. (2017) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2017.06.001 · Cited by 36
Bodyweight fluctuation is associated with increased risk of incident atrial fibrillation
Lee, H., Choi, E., Han, K., Lee, E., Moon, I., Lee, S., Cha, M., Oh, S., & Lip, G. Y. H. (2019) · Heart Rhythm · doi:10.1016/j.hrthm.2019.09.029 · Cited by 36
Impact of Lifestyle Modification on Atrial Fibrillation
Wingerter, R., Steiger, N. A., Burrows, A., & Estes, N. A. M. (2019) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2019.10.018 · Cited by 35
High overall cardiovascular risk and mortality in patients with atrial fibrillation and diabetes: A nationwide report
Karayiannides, S., Lundman, P., Friberg, L., & Norhammar, A. (2017) · Diabetes and Vascular Disease Research · doi:10.1177/1479164117735013 · Cited by 36
Obesity and atrial fibrillation: Prevalence, pathogenesis, and prognosis
Middeldorp, M. E., Kamsani, S. H., & Sanders, P. (2023) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2023.04.010 · Cited by 37
The impact of lifestyle intervention on atrial fibrillation
Hong, K. L., & Glover, B. M. (2017) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000470 · Cited by 31
Obesity and Atrial Fibrillation: Epidemiology, Pathogenesis and Effect of Weight Loss
Al‐Kaisey, A., & Kalman, J. M. (2021) · Arrhythmia & Electrophysiology Review · doi:10.15420/aer.2021.36 · Cited by 34
Atrial Fibrillation Symptoms and Sex, Race, and Psychological Distress
Gleason, K. T., Nazarian, S., & Himmelfarb, C. D. (2017) · The Journal of Cardiovascular Nursing · doi:10.1097/jcn.0000000000000421 · Cited by 33
Effect of Bariatric Surgery on Emergency Department Visits and Hospitalizations for Atrial Fibrillation
Shimada, Y. J., Tsugawa, Y., Camargo, C. A., Brown, D., & Hasegawa, K. (2017) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2017.06.026 · Cited by 34
The Effects of Cardiac Rehabilitation in Patients With Atrial Fibrillation: A Systematic Review
Reed, J. L., Terada, T., Chirico, D., Prince, S. A., & Pipe, A. (2018) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2018.07.014 · Cited by 33
Arrhythmogenic Substrates for Atrial Fibrillation in Obesity
Lubbers, E. R., Price, M. V., & Mohler, P. J. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01482 · Cited by 36
High variability in bodyweight is associated with an increased risk of atrial fibrillation in patients with type 2 diabetes mellitus: a nationwide cohort study
Lee, H., Choi, E., Han, K., Kim, D. H., Lee, E., Lee, S., Oh, S., & Lip, G. Y. H. (2020) · Cardiovascular Diabetology · doi:10.1186/s12933-020-01059-8 · Cited by 34
Atrial fibrillation: villain or bystander in vascular brain injury
Freedman, B., Kamel, H., Gelder, I. C. V., & Schnabel, R. B. (2020) · European Heart Journal Supplements · doi:10.1093/eurheartj/suaa166 · Cited by 33
Impact of pre‐ablation weight loss on the success of catheter ablation for atrial fibrillation
Peigh, G., Wasserlauf, J., Vogel, K. A., Kaplan, R. M., Pfenniger, A., Marks, D., Mehta, A., Chicos, A. B., Arora, R., Kim, H., et al. (2021) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.15141 · Cited by 33
Bariatric surgery reduces incidence of atrial fibrillation: a propensity score–matched analysis
Lynch, K., Mehaffey, J. H., Hawkins, R. B., Hassinger, T. E., Hallowell, P. T., & Kirby, J. L. (2018) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2018.11.021 · Cited by 36
Targeted therapy of underlying conditions improves quality of life in patients with persistent atrial fibrillation: results of the RACE 3 study
With, R. R. D., Rienstra, M., Smit, M. D., Weijs, B., Zwartkruis, V. W., Hobbelt, A. H., Alings, M., Tijssen, J. G. P., Brügemann, J., Geelhoed, B., et al. (2018) · EP Europace · doi:10.1093/europace/euy311 · Cited by 33
Meta-analysis of Effect of Modest (≥10%) Weight Loss in Management of Overweight and Obese Patients With Atrial Fibrillation
Aldaas, O. M., Lupercio, F. A., Han, F. T., Hoffmayer, K. S., Krummen, D. E., Ho, G., Raissi, F., Birgersdotter-Green, U. M., Feld, G. K., & Hsu, J. C. (2019) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2019.08.009 · Cited by 34
Incidence and Implications of Atrial Fibrillation/Flutter in Hypertension
Parcha, V., Patel, N., Kalra, R., Kim, J.-S., Gutiérrez, O. M., Arora, G., & Arora, P. K. (2020) · Hypertension · doi:10.1161/hypertensionaha.120.14690 · Cited by 32
Cardiac arrhythmias and conduction abnormalities in patients with type 2 diabetes
Rawshani, A., McGuire, D. K., Ömerovic, E., Sattar, N. A., McMurray, J. J. V., Smith, U., Redfors, B., Bergfeldt, L., Eliasson, B., Borén, J., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-27941-5 · Cited by 34
Aggressive Risk Factor Reduction Study for Atrial Fibrillation Implications for Ablation Outcomes
Pathak, R. K., Elliott, A. D., Lau, D. H., Middeldorp, M. E., Linz, D., Fitzgerald, J. L., Gupta, A. K., Ariyaratnam, J., Malik, V., Noubiap, J. J., et al. (2025) · JAMA Cardiology · doi:10.1001/jamacardio.2025.4007 · Cited by 35
The changing circumstance of atrial fibrillation ‐ progress towards precision medicine
Camm, A. J., Savelieva, I., Potpara, T., Hindriks, G., Pison, L., & Blomström‐Lundqvist, C. (2016) · Journal of Internal Medicine · doi:10.1111/joim.12478 · Cited by 30
Prevalence, Pharmacological Treatment, and Control of Cardiometabolic Risk Factors among Older People in Central Stockholm: A Population-Based Study
Wang, R., Fratiglioni, L., Liang, Y., Welmer, A., Xu, W., Mangialasche, F., Johnell, K., & Qiu, C. (2015) · PLoS ONE · doi:10.1371/journal.pone.0119582 · Cited by 31
Subclinical and Asymptomatic Atrial Fibrillation: Current Evidence and Unsolved Questions in Clinical Practice
Ballatore, A., Matta, M., Saglietto, A., Desalvo, P., Bocchino, P. P., Gaïta, F., Ferrari, G. M. D., & Anselmino, M. (2019) · Medicina · doi:10.3390/medicina55080497 · Cited by 33
Lifestyle management to prevent and treat atrial fibrillation
Gallagher, C., Hendriks, J. M. L., Mahajan, R., Middeldorp, M. E., Elliott, A. D., Pathak, R. K., Sanders, P., & Lau, D. H. (2016) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2016.1179581 · Cited by 29
Self-citation
Approach to Obesity in the Older Population
Buch, A., Marcus, Y., Shefer, G., Zimmet, P., & Stern, N. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab359 · Cited by 31
Beyond cardioversion, ablation and pharmacotherapies: Risk factors, lifestyle change and behavioral counseling strategies in the prevention and treatment of atrial fibrillation
Mehta, N. K., Strickling, J. E., Mark, E., Swinehart, S., Puthumana, J., Lavie, C. J., Haines, D. E., & Franklin, B. A. (2021) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2021.05.002 · Cited by 31
Modulation of NOX2 causes obesity-mediated atrial fibrillation
Sridhar, A., DeSantiago, J., Chen, H., Pavel, M. A., Ly, O. T., Owais, A., Barney, M., Jousma, J., Nukala, S. B., Abdelhady, K., et al. (2024) · Journal of Clinical Investigation · doi:10.1172/jci175447 · Cited by 29
Atrial fibrillation in the cardiometabolic patient
Sensi, F. D., Costantino, S., Limbruno, U., & Paneni, F. (2019) · Minerva Medica · doi:10.23736/s0026-4806.18.05882-2 · Cited by 29
Sleep apnoea has a dose-dependent effect on atrial remodelling in paroxysmal but not persistent atrial fibrillation: a high-density mapping study
Nalliah, C. J., Wong, G. R., Lee, G., Voskoboinik, A., Kee, K., Goldin, J., Watts, T. W., Linz, D., Wirth, D., Parameswaran, R., et al. (2021) · EP Europace · doi:10.1093/europace/euaa275 · Cited by 29
Repeat catheter ablation for atrial fibrillation
Brahier, M. S., Friedman, D. J., Bahnson, T. D., & Piccini, J. P. (2023) · Heart Rhythm · doi:10.1016/j.hrthm.2023.12.003 · Cited by 28
Interactions between atrial fibrosis and inflammation in atrial fibrillation
Pang, Z., Ren, Y., & Yao, Z. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1578148 · Cited by 31
Assessment of Atrial Fibrillation and Ventricular Arrhythmia Risk after Bariatric Surgery by P Wave/QT Interval Dispersion
Yılmaz, M., Altın, C., Tekin, A., Erol, T., Arer, İ. M., Nursal, T. Z., Törer, N., Erol, V., & Müderrisoğlu, H. (2017) · Obesity Surgery · doi:10.1007/s11695-017-2923-z · Cited by 28
Endothelial dysfunction and vascular maladaptation in atrial fibrillation
Qin, S., Boidin, M., Buckley, B. J. R., Lip, G. Y. H., & Thijssen, D. H. J. (2021) · European Journal of Clinical Investigation · doi:10.1111/eci.13477 · Cited by 28
Cardiovascular, kidney, and metabolic health: an actionable vision for heart failure prevention
Ostrominski, J. W., CHENG, A. Y. Y., Nelson, A. J., Neuen, B. L., Sattar, N. A., Tuttle, K. R., & Vaduganathan, M. (2025) · The Lancet · doi:10.1016/s0140-6736(25)01384-4 · Cited by 32
Estudo Safira: reflexões sobre a prevalência e os padrões de tratamento de fibrilhação auricular e risco cardiovascular em 7500 indivíduos com 65 ou mais anos
Monteiro, P. F. (2018) · Revista Portuguesa de Cardiologia · doi:10.1016/j.repc.2017.08.006 · Cited by 28
Guía ESC 2020 sobre el diagnóstico y tratamiento de la fibrilación auricular, desarrollada en colaboración de la European Association of Cardio-Thoracic Surgery (EACTS)
Hindricks, G., Potpara, T., Dagres, N., Arbelo, E., Bax, J. J., Blomström‐Lundqvist, C., Boriani, G., Castellà, M., Dan, G., Dilaveris, P., et al. (2021) · Revista Española de Cardiología · doi:10.1016/j.recesp.2020.10.022 · Cited by 34
Persistent Atrial Fibrillation From the Onset
Lim, H. S., Denis, A., Middeldorp, M. E., Lau, D. H., Mahajan, R., Derval, N., Albenque, J., Bovéda, S., Zellerhoff, S., Yamashita, S., et al. (2016) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2015.12.014 · Cited by 28
Body mass and atrial fibrillation risk: Status of the epidemiology concerning the influence of fat versus lean body mass
Fenger‐Grøn, M., Vinter, N., & Frost, L. (2019) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2019.05.009 · Cited by 28
Obesity and cardiovascular disease: Risk assessment, physical activity, and management of complications
Perone, F., Spadafora, L., Pratesi, A., Nicolaio, G., Pala, B., Franco, G., Ruzzolini, M., & Ambrosetti, M. (2024) · International Journal of Cardiology Cardiovascular Risk and Prevention · doi:10.1016/j.ijcrp.2024.200331 · Cited by 34
Abordaje de la fibrilación auricular en pacientes con cáncer activo. Documento de consenso de expertos y recomendaciones
López‐Fernández, T., Martín‐Garcia, A., Rabadán, I. R., Mitroi, C. D., Mazón‐Ramos, P., Díez‐Villanueva, P., Escobar, C., Alonso‐Martín, C., Salinas, G. L. A., Arenas, M., et al. (2019) · Revista Española de Cardiología · doi:10.1016/j.recesp.2019.03.017 · Cited by 26
Patients’ Experiences of Living with Atrial Fibrillation: A Mixed Methods Study
Stridsman, M., Strömberg, A., Hendriks, J., & Walfridsson, U. (2019) · Cardiology Research and Practice · doi:10.1155/2019/6590358 · Cited by 26
The effect of obesity, hypertension, diabetes mellitus, alcohol, and sleep apnea on the risk of atrial fibrillation
Čarná, Z., & Osmancik, P. P. (2021) · Physiological Research · doi:10.33549/physiolres.934744 · Cited by 26
Hypertension and atrial fibrillation
Middeldorp, M. E., Ariyaratnam, J., Kamsani, S. H., Albert, C. M., & Sanders, P. (2022) · Journal of Hypertension · doi:10.1097/hjh.0000000000003278 · Cited by 27
The challenges of real-world implementation of web-based shared care software: the HopSCOTCH Shared-Care Obesity Trial in Children
Lycett, K., Wittert, G., Gunn, J. M., Hutton, C., Clifford, S. A., & Wake, M. A. (2014) · BMC Medical Informatics and Decision Making · doi:10.1186/1472-6947-14-61 · Cited by 26
Atrial fibrillation risk factor management with a plant‐based diet: A review
Storz, M. A., & Helle, P. (2019) · Journal of Arrhythmia · doi:10.1002/joa3.12254 · Cited by 26
Multimorbidity in patients with atrial fibrillation
Lobeek, M., Middeldorp, M. E., Gelder, I. C. V., & Rienstra, M. (2024) · Open Heart · doi:10.1136/openhrt-2024-002641 · Cited by 26
JCS 2023 Guideline on Diagnosis and Treatment of Sleep Disordered Breathing in Cardiovascular Disease
Kasai, T., Kohno, T., Shimizu, W., Ando, S., Joho, S., Osada, N., Kato, M., Kario, K., Shiina, K., Tamura, A., et al. (2024) · Circulation Journal · doi:10.1253/circj.cj-23-0489 · Cited by 25
Influence of exercise training on the left atrium: implications for atrial fibrillation, heart failure, and stroke
Elliott, A. D., Ariyaratnam, J., Howden, E. J., Gerche, A. L., & Sanders, P. (2023) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00322.2023 · Cited by 25
The Future of Arrhythmias and Electrophysiology
Albert, C. M., & Stevenson, W. G. (2016) · Circulation · doi:10.1161/circulationaha.116.023519 · Cited by 25
Patient-Centered Educational Resources for Atrial Fibrillation
Gallagher, C., Rowett, D. S., Nyfort‐Hansen, K. S., Simmons, S., Brooks, A. G., Moss, J. R., Middeldorp, M. E., Hendriks, J., Jones, T., Mahajan, R., et al. (2019) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2019.08.007 · Cited by 25
Long-term outcomes after hospitalization for atrial fibrillation or flutter
Ngo, L., Peng, Y., Denman, R. A., Yang, I. A., & Ranasinghe, I. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae204 · Cited by 24
Effects of Δ9-Tetrahydrocannibinol (THC) on Obesity at Different Stages of Life: A Literature Review
Fearby, N. L., Penman, S. L., & Thanos, P. K. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19063174 · Cited by 27
Effect of weight loss on recurrence of atrial fibrillation after ablative therapy: a systematic review and meta-analysis
Park, D. Y., An, S., Murthi, M., Kattoor, A. J., Kaur, A., Ravi, V., Huang, H. D., & Vij, A. (2022) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-022-01168-2 · Cited by 24
Body Mass Index and Body Fat Distribution and New-Onset Atrial Fibrillation. Sub study of The European Prospective Investigation Into Cancer and Nutrition in Norfolk (EPIC-Norfolk) Study
Neefs, J., Boekholdt, S., Khaw, K., Luben, R. N., Pfister, R., Wareham, N., Meulendijks, E., Sanders, P., & de Groot, J. D. (2019) · NMCD. Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2019.03.005 · Cited by 22
PREvention of recurrent arrhythmias with Mediterranean diet (PREDIMAR) study in patients with atrial fibrillation: Rationale, design and methods
Barrio-López, M. T., Ruiz‐Canela, M., Ramos, P., Tercedor, L., Ibáñez, J. L., Ortiz, M., Goñi, L., Ibáñez-Críado, A., Ruiz, R. M., García‐Bolao, I., et al. (2019) · American Heart Journal · doi:10.1016/j.ahj.2019.10.009 · Cited by 23
Sleep Disordered Breathing, Obesity and Atrial Fibrillation: A Mendelian Randomisation Study
Ardissino, M., Reddy, R. K., Slob, E. A. W., Patel, K. H. K., Ryan, D. K., Gill, D., & Ng, F. S. (2022) · Genes · doi:10.3390/genes13010104 · Cited by 25
Pathophysiology and clinical relevance of atrial myopathy
Tubeeckx, M., Keulenaer, G. W. D., Heidbüchel, H., & Segers, V. F. M. (2024) · Basic Research in Cardiology · doi:10.1007/s00395-024-01038-0 · Cited by 25

Authors: Abed, H. S., Wittert, G. A., Leong, D. P., Shirazi, M. G., Bahrami, B., Middeldorp, M. E., Lorimer, M. F., Lau, D. H., Antic, N. A., Brooks, A. G., Abhayaratna, W. P., Kalman, J. M., & Sanders, P.
Affiliations: Royal Adelaide Hospital (AU)
The University of Adelaide (AU)
Repatriation General Hospital (AU)
Australian National University (AU)
The Royal Melbourne Hospital (AU)
ORCID: Wittert, Gary A.
Leong, Darryl P.
Bahrami, Bobak
Middeldorp, Melissa E.
Lorimer, Michelle F.
Lau, Dennis H.
Abhayaratna, Walter P.
Kalman, Jonathan M.
Sanders, Prashanthan
Venue: JAMA
Publisher: American Medical Association (AMA)
Published: 2013-11-20
Volume: 310
Issue: 19
Pages: 2050
ISSN: 0002-9955 (ISSN-L)
0098-7484
DOI: 10.1001/jama.2013.280521
OpenAlex: W1963940525
Cited by: 776
References: 52
Citations by year: 2026: 51 · 2025: 64 · 2024: 69 · 2023: 53 · 2022: 56 · 2021: 76 · 2020: 50 · 2019: 70 · 2018: 52 · 2017: 81 · 2016: 63 · 2015: 51 · 2014: 35 · 2013: 4
FWCI: 34.64
Type: journal article
Language: en
Open access: closed
Locations: JAMA (publishedVersion)
PubMed (publishedVersion)
Flinders Academic Commons (Flinders University) (publishedVersion)
Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
Flinders Academic Commons (Flinders University) (submittedVersion)
ANU Open Research (Australian National University) (submittedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
Keywords: weight loss, obesity, cardiometabolic risk factors, symptom burden, symptom severity, cardiac remodeling, left atrial area, interventricular septum thickness, lifestyle intervention, overweight patients, Holter monitoring, cardiac structure, risk factor control, weight management, lifestyle advice
MeSH terms: Aged, Atrial Fibrillation, Diet, Reducing, Echocardiography, Fish Oils, Heart Atria, Humans, Life Style, Male, Middle Aged, Obesity, Risk Factors, Severity of Illness Index, Weight Loss, Treatment Outcome, Overweight

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Effect of Weight Reduction and Cardiometabolic Risk Factor Management on Symptom Burden and Severity in Patients With Atrial Fibrillation: A Randomized Clinical Trial

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks