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Cited by 268

The DOI matches its OpenAlex record; 1 of the 1 references it cites were found in a registry or an index.

The relative risk of incident coronary heart disease associated with recently stopping the use of beta-blockers

Bruce M. Psaty·1990·JAMA

Abstract

We conducted a population-based, case-control study of risk factors for first events of coronary heart disease in patients with high blood pressure. All subjects had hypertension treated with medication. The 248 cases presented with new coronary heart disease from 1982 through 1984, and the 737 controls were a probability sample of health maintenance organization patients free of coronary heart disease. The health maintenance organization's computerized pharmacy database identified recent stoppers--patients who did not fill their prescriptions regularly enough to be at least 80% compliant. After adjustment for potential confounding factors, subjects who had recently stopped using beta-blockers had a transient fourfold increase in the relative risk of coronary heart disease (relative risk, 4.5; 95% confidence interval, 1.1 to 18.5). The association was specific to beta-blockers but not diuretics. A withdrawal syndrome immediately following the cessation of beta-blocker use may be an acute precipitant of angina and myocardial infarction in hypertensive patients who have no prior history of coronary heart disease.

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OpenAlex · 10.1001/jama.263.12.1653

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Metadata

Authors
Psaty, B. M.
Venue
JAMA
Publisher
American Medical Association
Published
1990-03-23
Volume
263
Issue
12
Pages
1653-1657
ISSN
0002-9955 (ISSN-L)
OpenAlex
W4255783390
Cited by
268
References
1
FWCI
8.44
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.