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Burden of Disease—Implications for Future Research
Abstract
One overall challenge for public health and medicine in the future is to allocate available resources effectively to reduce major causes of disease burden globally and to decrease health disparities between poor and affluent populations. The major risk factors for death and disability worldwide are malnutrition; poor water supply, sanitation, and personal and domestic hygiene; unsafe sexual behavior; tobacco use; alcohol use; occupational hazards; hypertension; physical inactivity; illicit drugs; and air pollution. The challenge for research in the 21st century is to maintain and improve life expectancy and the quality of life that was achieved for most of the world's population during the 20th century.
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“In 2020, IHD and depression are expected to be among the top contributors to the disease-burden worldwide.”
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Metadata
- Authors
- Michaud, C. M.
- Affiliations
- Harvard University (US)
- Corresponding author
- Michaud, Catherine M.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2001-02-07
- Volume
- 285
- Issue
- 5
- Pages
- 535
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2034987992
- Cited by
- 594
- References
- 14
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 8 · 2023: 14 · 2022: 11 · 2021: 13 · 2020: 14 · 2019: 13 · 2018: 18 · 2017: 13 · 2016: 14 · 2015: 14 · 2014: 33 · 2013: 32 · 2012: 24
- FWCI
- 98.29
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- DigitalGeorgetown (Georgetown University Library) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Global Health and Epidemiology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Global Public Health Policies and Epidemiology
- Keywords
- disease burden, global health, health disparities, malnutrition, water and sanitation, unprotected sex, tobacco use, alcohol consumption, occupational hazards, hypertension, physical inactivity, illicit drugs, air pollution, life expectancy, quality of life, resource allocation
- MeSH terms
- Humans, Life Expectancy, Public Health, Quality of Life, Research, Global Health, Cost of Illness
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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