The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Trends in Androgen Prescribing in the United States, 2001 to 2011
Open accessAbstract
Although commercial sales of androgen replacement therapy (ART) have increased substantially in recent years,1,2 to our knowledge, no national population-based studies of this treatment have been reported. In view of the conflicting evidence on the risks and benefits of ART,3-7 understanding androgen prescribing patterns in the United States is important from both a clinical and a public health perspective. We used data from Clinformatics DataMart (CDM), one of the nation's largest commercial health insurance populations, to examine androgen prescribing patterns in the United States over the past decade.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“the number of patients diagnosed and treated for hypogonadism over the past decade has increased significantly, with an exponential rise in prescribed T in many developed countries.”
From Challenges in Testosterone Measurement, Data Interpretation, and Methodological Appraisal of Interventional Trials (2016) · cites this paper as [6]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Adverse Events Associated with Testosterone Administration
Basaria, S., Coviello, A. D., Travison, T. G., Storer, T. W., Farwell, W. R., Jette, A. M., Eder, R., Tennstedt, S., Ulloor, J., Zhang, A., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1000485 · Cited by 1,494
Calof, O. M., Singh, A. B., Lee, M. L., Kenny, A. M., Urban, R. J., Tenover, J. L., & Bhasin, S. (2005) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/60.11.1451 · Cited by 728
Self-citationWang, C., Cunningham, G., Dobs, A., Iranmanesh, A., Matsumoto, A. M., Snyder, P. J., Weber, T., Berman, N., Hull, L., & Swerdloff, R. S. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-032006 · Cited by 656
Srinivas-Shankar, U., Roberts, S. A., Connolly, M. J., O'Connell, M. D. L., Adams, J. E., Oldham, J. A., & Wu, F. C. W. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-1251 · Cited by 629
Haddad, R. M., Kennedy, C. C., Caples, S. M., Tracz, M. J., Boloña, E. R., Sideras, K., Úraga, M. V., Erwin, P. J., & Montori, V. M. (2007) · Mayo Clinic Proceedings · doi:10.4065/82.1.29 · Cited by 329
Bhasin, S., Singh, A. B., Mac, R. P., Carter, B., Lee, M. I., & Cunningham, G. R. (2003) · Journal of Andrology · doi:10.1002/j.1939-4640.2003.tb02676.x · Cited by 219
Flagged first, then by citations
Cited by
Sorted by citations
Items 301–335 of 335
Heidelbaugh, J., Grech, A., & Miner, M. (2016) · Springer eBooks · doi:10.1007/978-3-319-26091-4_13
Hormonal Evaluation and Therapy of Erectile Dysfunction
Hockenberry, M. S., & Masson, P. (2016) · Springer eBooks · doi:10.1007/978-3-319-31587-4_7
Iyer, R., & Handelsman, D. J. (2017) · Springer eBooks · doi:10.1007/978-3-319-46086-4_19
Fertility Preservation in Hypogonadal Men
Carrasquillo, R. J., & Ramasamy, R. (2017) · Springer eBooks · doi:10.1007/978-3-319-42396-8_9
Antiaging and Performance-Enhancing Drugs
Yaseen, Z. (2018) · Springer eBooks · doi:10.1007/978-3-319-16223-2_6
Testosterone Therapy: Do American and European Clinicians Have Different Approaches?
Trost, L. W., & Zitzmann, M. (2018) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2018.07.010
Debunking Internet Myths: What Is the Best Approach?
Eschler, D. C., & Leffert, J. D. (2019) · Springer eBooks · doi:10.1007/978-3-030-22720-3_5
Testosterone Replacement Therapy: Playing Catch-up With Patients.
Sheahan, W. T., Martinez, S., & Golden, A. G. (2015) · Europe PMC (PubMed Central)
Testosterone Therapy: Risk Factor for Venous Thromboembolism?
Moll, S. (2017) · The Hematologist · doi:10.1182/hem.v14.2.7119
Internet Transparency of Local Men’s Health Clinics in Nebraska
Jiang, J., Stegman, J., & Deibert, C. M. (2020) · Graduate Medical Education Research Journal · doi:10.32873/unmc.dc.gmerj.2.2.004
Erythrocytosis in Patients on Testosterone Therapy
Desai, A. P., & Go, R. S. (2021) · Springer eBooks · doi:10.1007/978-3-030-77111-9_2
Fertility Preservation in Hypogonadal Men
Cohen, J. A., Rezk, A. H., & Ramasamy, R. (2022) · Springer eBooks · doi:10.1007/978-3-030-47767-7_39
Hormone Replacement Therapy in Men
Pham, C. H., Wang, C., & Swerdloff, R. S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.99449-2
Tozzoli, R., Metus, P., Simula, M. P., Fadi, E., D’Aurizio, F., & Vitillo, M. (2021) · La Rivista Italiana della Medicina di Laboratorio - Italian Journal of Laboratory Medicine · doi:10.23736/s1825-859x.20.00077-8
Marson, L., Romanzi, L. J., & Miner, M. M. (2014) · The Journal of Sexual Medicine · doi:10.1111/jsm.12579
Minhas, S., Tharakan, T., & Miah, S. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.735091493.793556544
Faculty Opinions recommendation of Pharmacology of testosterone replacement therapy preparations.
Minhas, S., Miah, S., & Tharakan, T. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.727213690.793556658
Neues und praktisch Relevantes aus der gynäkologischen Endokrinologie und Reproduktionsmedizin
von Wolff, M., & Stute, P. (2016) · Gynäkologische Endokrinologie · doi:10.1007/s10304-016-0059-1
Callegari, M., Pominville, R., Zhou, C., Piyevsky, B., Jesse, E., Prunty, M. C., Loeb, A., Thirumavalavan, N., & Ghayda, R. A. (2022) · Research Square · doi:10.21203/rs.3.rs-1735926/v1
Male Fertility and Testosterone Therapy
Andino, J. J., & Dupree, J. M. (2023) · Cambridge University Press eBooks · doi:10.1017/9781009197533.035
The Business Landscape of Men’s Health
Weinberger, J. M., & Mills, J. N. (2023) · Cambridge University Press eBooks · doi:10.1017/9781009197533.003
The good, the bad, and the ugly: Correct, questionable, and misuse of testosterone
Huhtaniemi, I. T. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13432-6.00022-8
Hussain, M. R., Abdelgadir, O., Polychronopoulou, E., Tsilidis, K. K., Alzweri, L. M., Tezanos, A. G. V., Baillargeon, J., Canfield, S. E., Kuo, Y., & López, D. S. (2024) · Andrology · doi:10.1111/andr.13616
Self-citationMissbrauch und Missbrauch von Testosteron
Iyer, R., & Handelsman, D. J. (2024) · Springer eBooks · doi:10.1007/978-3-031-65245-5_23
Hormone replacement therapy, male
Wang, C., & Swerdloff, R. S. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-13825-6.00263-6
Testosterone and Prostate Cancer
Khera, M., Saffati, G., & Rendon, D. O. (2025) · Springer eBooks · doi:10.1007/978-3-031-96376-6_32
Testosterone Effects on the Prostate: Focusing on Benign Prostatic Hyperplasia
Grutman, A. J., Su, Z. T., & Herati, A. S. (2025) · Springer eBooks · doi:10.1007/978-3-031-96376-6_31 · Cited by 1
Testosterone Measurement, Use and Misuse
Handelsman, D. J. (2025) · Springer eBooks · doi:10.1007/978-3-031-96376-6_17
Newman, M. S., Smeaton, J., Gillson, G., & Jaferi, A. (2026) · Frontiers in Reproductive Health · doi:10.3389/frph.2026.1804311
Endocrine Support for the Aesthetic Patient
Parsa, A. A., & Parsa, F. D. (2026) · Springer eBooks · doi:10.1007/978-3-032-03840-1_46
Androgen Awareness: Navigating Testosterone Replacement Therapy in Total Joint Arthroplasty
Ganz, M. P., Mont, M. A., & Scuderi, G. R. (2026) · The Journal of Arthroplasty · doi:10.1016/j.arth.2026.06.013
Pharmacoepidemiology of testosterone prescribing in Australia, 2010-2023
Gialouris, J. V., Hou, W., Lim, S., & Handelsman, D. J. (2026) · European Journal of Endocrinology · doi:10.1093/ejendo/lvag158
Adolf, J., & Raykov, G. (2026) · Drug Testing and Analysis · doi:10.1002/dta.70159
Current Evidence on Late-Onset Hypogonadism in Primary Care: A Scoping Review Protocol
Tashiro, N., Otsuka, Y., Soejima, Y., Masuda, Y., Tokumasu, K., Sakurada, Y., Matsuki, N., Mitsuda, E., Shiraishi, K., Nakatsuka, M., et al. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15207776
Metadata
- Authors
- Baillargeon, J., Urban, R. J., Ottenbacher, K. J., Pierson, K. S., & Goodwin, J. S.
- Affiliations
- The University of Texas Medical Branch at Galveston (US)
- Venue
- JAMA Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 2013-08-12
- Volume
- 173
- Issue
- 15
- Pages
- 1465
- ISSN
- 2168-6106 (ISSN-L)
- PMC
- PMC4100547
- OpenAlex
- W1975148982
- Cited by
- 336
- References
- 6
- Citations by year
- 2026: 9 · 2025: 10 · 2024: 16 · 2023: 14 · 2022: 18 · 2021: 18 · 2020: 19 · 2019: 21 · 2018: 26 · 2017: 35 · 2016: 46 · 2015: 49 · 2014: 47 · 2013: 8
- FWCI
- 39.33
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- JAMA Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (UL1TR000071)
- National Institute on Aging (5P30AG02482, P30AG024832)
- National Cancer Institute (K05CA134923)
- National Center for Research Resources (UL1RR029876)
- National Center for Advancing Translational Sciences
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R24HD065702)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Keywords
- testosterone replacement therapy, testosterone, health insurance claims data, commercial health insurance, temporal trends, disease surveillance
- MeSH terms
- Adult, Androgens, Humans, Male, Middle Aged, Drug Prescriptions, United States, Hormone Replacement Therapy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review