Cited by 186Balance, Gait, and Falls PreventionPhysical Activity and HealthFrailty in Older Adults

The DOI matches its Crossref record; 76 of the 80 references it cites were found in a registry or an index.

Association of Long-term Exercise Training With Risk of Falls, Fractures, Hospitalizations, and Mortality in Older Adults: A Systematic Review and Meta-analysis

Open access

de Souto Barreto, Philipe, Rolland, Yves, Vellas, Bruno, Maltais, Mathieu·2019·JAMA Internal Medicine

DOI 10.1001/jamainternmed.2018.5406PMC PMC6439708

Open this paper in CoChat — free account Open PDF

Abstract

Importance: Long-term exercise benefits on prevalent adverse events in older populations, such as falls, fractures, or hospitalizations, are not yet established or known. Objective: To systematically review and investigate the association of long-term exercise interventions (≥1 year) with the risk of falls, injurious falls, multiple falls, fractures, hospitalization, and mortality in older adults. Data Sources: PubMed, Cochrane Central Register of Controlled Trials, SportDiscus, PsychInfo, and Ageline were searched through March 2018. Study Selection: Exercise randomized clinical trials (RCTs) with intervention length of 1 year or longer, performed among participants 60 years or older. Data Extraction and Synthesis: Two raters independently screened articles, abstracted the data, and assessed the risk of bias. Data were combined with risk ratios (RRs) using DerSimonian and Laird's random-effects model (Mantel-Haenszel method). Main Outcomes and Measures: Six binary outcomes for the risk of falls, injurious falls, multiple falls (≥2 falls), fractures, hospitalization, and mortality. Results: Forty-six studies (22 709 participants) were included in the review and 40 (21 868 participants) in the meta-analyses (mean [SD] age, 73.1 [7.1] years; 15 054 [66.3%] of participants were women). The most used exercise was a multicomponent training (eg, aerobic plus strength plus balance); mean frequency was 3 times per week, about 50 minutes per session, at a moderate intensity. Comparator groups were often active controls. Exercise significantly decreased the risk of falls (n = 20 RCTs; 4420 participants; RR, 0.88; 95% CI, 0.79-0.98) and injurious falls (9 RTCs; 4481 participants; RR, 0.74; 95% CI, 0.62-0.88), and tended to reduce the risk of fractures (19 RTCs; 8410 participants; RR, 0.84; 95% CI, 0.71-1.00; P = .05). Exercise did not significantly diminish the risk of multiple falls (13 RTCs; 3060 participants), hospitalization (12 RTCs; 5639 participants), and mortality (29 RTCs; 11 441 participants). Sensitivity analyses provided similar findings, except the fixed-effect meta-analysis for the risk of fracture, which showed a significant effect favoring exercisers (RR, 0.84; 95% CI, 0.70-1.00; P = .047). Meta-regressions on mortality and falls suggest that 2 to 3 times per week would be the optimal exercise frequency. Conclusions and Relevance: Long-term exercise is associated with a reduction in falls, injurious falls, and probably fractures in older adults, including people with cardiometabolic and neurological diseases.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1001/jamainternmed.2018.5406

Cites

76 of 76 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552
The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
Higgins, J. P. T., Altman, D. G., Gotzsche, P. C., Juni, P., Moher, D., Oxman, A. D., Savovic, J., Schulz, K. F., Weeks, L., Sterne, J. A. C., et al. (2011) · BMJ · doi:10.1136/bmj.d5928 · Cited by 33,817
The “Golden Age” of Probiotics: A Systematic Review and Meta-Analysis of Randomized and Observational Studies in Preterm Infants
Dermyshi, E., Wang, Y., Yan, C., Hong, W., Qiu, G., Gong, X., & Zhang, T. (2017) · Neonatology · doi:10.1159/000454668 · Cited by 24,586
Exercise and Physical Activity for Older Adults
Chodzko-Zajko, W. J., Proctor, D. N., Fiatarone Singh, M. A., Minson, C. T., Nigg, C. R., Salem, G. J., & Skinner, J. S. (2009) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181a0c95c · Cited by 5,153
Interventions for preventing falls in older people living in the community
Gillespie, L. D., Robertson, M. C., Gillespie, W. J., Sherrington, C., Gates, S., Clemson, L., & Lamb, S. E. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007146.pub3 · Cited by 3,966
Untitled work
O'Connor (2009) · doi:10.1001/jama.2009.454 · Cited by 2,173
Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial
Pahor, M., Guralnik, J. M., Ambrosius, W. T., Blair, S., Bonds, D. E., Church, T. S., Espeland, M. A., Fielding, R. A., Gill, T. M., Groessl, E. J., et al. (2014) · JAMA · doi:10.1001/jama.2014.5616 · Cited by 1,427

Flagged first, then by citations

Show all 80 references

4 of the 80 references couldn’t be matched to a known paper.

Sorted by citations

Items 101–186 of 186

Comprehensive Geriatric Assessment
Dharmarajan, T. S. (2021) · Springer eBooks · doi:10.1007/978-3-319-90761-1_8-1 · Cited by 3
Cognitive function and fall risk among nursing home older adults: the moderated mediating model of physical activity and social support
Zhao, X., Feng, Y. Y., Jin, Y., Song, Y., & Guo, X. (2025) · Geriatric Nursing · doi:10.1016/j.gerinurse.2025.103461 · Cited by 2
Midlife physical activity, BMI, and hip fracture risk five decades later in men: a NOREPOS study
Landgraff, I. K., Myrstad, M., Ranhoff, A. H., Talsnes, O., Holvik, K., & Meyer, H. E. (2026) · Archives of Osteoporosis · doi:10.1007/s11657-026-01657-1 · Cited by 3
Benefits of Two 24-Week Interactive Cognitive–Motor Programs on Body Composition, Lower-Body Strength, and Processing Speed in Community Dwellings at Risk of Falling: A Randomized Controlled Trial
Rosado, H., Pereira, C. L. N., Bravo, J., Carvalho, J., & Raimundo, A. M. D. M. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19127117 · Cited by 2
“Recent studies have shown an association between long-term exercise (at least 24 weeks, three times per week at a moderate intensity) and a reduction in the number of falls or fall-related fractures in community-dwelling older people [1,9].”
Background
Effektivität eines körperlichen Trainings zur Reduktion niedrig-traumatischer und osteoporotischer Hauptfrakturen in Erwachsenen. Systematische Übersichtsarbeit und Meta-Analyse
Shojaa, M., Hoffmann, I., Kohl, M., von Stengel, S., Becker, C., Gosch, M., Jakob, F. J., Kerschan‐Schindl, K., Kladny, B., Lange, U., et al. (2023) · Osteologie/Osteology · doi:10.1055/a-2067-4323 · Cited by 2
Trainingsziele und Risikokategorisierung im Spannungsfeld körperliches Training und Frakturprophylaxe: Ansatzpunkte für individualisierte Trainingsprogramme
Mohebi, R., von Stengel, S., Kohl, M., Jakob, F. J., Kerschan‐Schindl, K., Lange, U., Peters, S., Schöne, D., Thomasius, F. E., Becker, C., et al. (2023) · Osteologie/Osteology · doi:10.1055/a-2075-7106 · Cited by 2
“Tatsächlich belegen systematische Übersichtsarbeiten und Meta-Analysen einen signifikant positiven Effekt körperlichen Trainings auf sturzinduzierte Frakturen [4, 5], niedrigtraumatische Gesamtfrakturen [6–8] sowie osteoporotische Hauptfrakturen [6, 7].”
Background
Osteoporosis Treatment Strategies: Current Concepts
Weiser, M., Johns, W. L., & Hozack, B. A. (2024) · SurgiColl · doi:10.58616/001c.84133 · Cited by 3
Neglect in Older Adults: A Sociodemographic and Health Approach in the Portuguese Context
Jesus, J. C., von Humboldt, S., Soares, L., & Leal, I. M. P. (2024) · Social Sciences · doi:10.3390/socsci13080419 · Cited by 2
Exercise prevents fall-related injuries in older people
Lord, S. R. (2019) · Nature Reviews Endocrinology · doi:10.1038/s41574-019-0175-9 · Cited by 2
Physical fitness, balance and falls in older adults
Loureiro, V., Gomes, M., & Gradek, J. (2019) · Journal of Kinesiology and Exercise Sciences · doi:10.5604/01.3001.0013.7802 · Cited by 2
“[26] Barreto PD, Rolland Y, Vellas B, Maltais M: Association of Long-term Exercise Training With Risk of Falls, Fractures, Hospitalizations, and Mortality in Older Adults A Systematic Review and Meta-analysis.”
Background
Osteosarcopenia and risk of falls: a concise review
Alessandro de, S. I. R. E., Calafiore, D., Curci, C., Lippi, L., & Invernizzi, M. (2024) · International Journal of Bone Fragility · doi:10.57582/ijbf.240402.063 · Cited by 3
Efficacy of a Multicomponent Occupational Therapy Intervention on Balance, Functional Mobility, and Proprioception in Institutionalized Older Adults: A Randomized Controlled Pilot Trial
Caña-Pino, A., & Marín-Rubio, A. (2025) · Healthcare · doi:10.3390/healthcare13182287 · Cited by 1
“Such fall rates align with global data indicating 2.4 falls/person-year in institutionalized adults and major risk associations like comorbidity and polypharmacy [5,6].”
Influential
Effects of functional task training on physical performance in older adults: a systematic review and meta-analysis
Nieves-Silva, R., Ríos, L. J. C., Ríos, I. J. C., García, D. M., Jiménez-Lupión, D., & Jerez‐Mayorga, D. (2025) · European Geriatric Medicine · doi:10.1007/s41999-025-01310-z · Cited by 1
Nationwide assessment of fall risk and protective factors among older adults in Saudi Arabia
Alharbi, A. A., Albalwi, A. A., Amer, H. S. A., Alamrani, S. A., Albalawi, H., Alrashedi, F. D., Muthaffar, M. Y., Albalwi, M. A., Alshehre, Y. M., Bakhsh, H. R., et al. (2025) · PLoS ONE · doi:10.1371/journal.pone.0332900 · Cited by 1
Impact of a two-phase robotic-assisted and home-based training program on falls and fall risk in older adults: a multicenter randomized controlled trial
Kwag, E., Luca, A. D., Marchesi, G., Squeri, V., Ramm, P., Hochheim, M., Wunderlich, M., Zijlstra, W., & Morat, T. (2025) · Trials · doi:10.1186/s13063-025-09380-x · Cited by 1
“…pathway to strengthen both effectiveness and sustainability is a sequential hybrid model: a supervised, center-based robotic-assisted phase to establish technique, safety, and adequate dose, followed by a tailored home-based program to support maintenance and real-world transfer [15, 16, 23, 24].”
Surgical fixation of clavicle fractures in the elderly: utilization and compensation over two decades
Hop, J. C., Richman, E. H., Marchetti, D. C., Royster, B. W., Gorman, M. A., & Alfonso, N. A. (2026) · European Journal of Orthopaedic Surgery & Traumatology · doi:10.1007/s00590-026-04657-6 · Cited by 1
Effects of exercise interventions on fall-related injuries in community-dwelling older adults: an updated systematic review and meta-analysis
Ge, B., Luo, J., Cheng, X., Wang, D., Liu, R., & Liao, X. (2026) · Frontiers in Public Health · doi:10.3389/fpubh.2026.1916495 · Cited by 1
POLÍTICAS PÚBLICAS PARA A ORIENTAÇÃO DA VOCAÇÃO, DETECÇÃO E DESENVOLVIMENTO DE TALENTOS ESPORTIVOS
Bispo, M. D. C., Santos, A. C., de Souza, E. A., Bastos, E. C., Vilhena, A. M. P., Mendonça, M. B., Zanoni, É. M., Gastélum-Cuadras, G., Júnior, R. J. N., Carvalho, M. C. G. D. A., et al. (2021) · doi:10.22533/at.ed.22721070611 · Cited by 1
Obesity in the elderly: peculiarities of treatment in outpatient practice
Суплотова, Л. А., Alieva, O. O., Сергеевна, Д. Т., & Makarova, O. B. (2023) · Obesity and metabolism · doi:10.14341/omet12919 · Cited by 2
Comment on “Association of Left Atrial Function With Frailty: The Atherosclerosis Risk in Communities ( ARIC ) Study”
Naharcı, M. İ. (2025) · Journal of the American Geriatrics Society · doi:10.1111/jgs.19476 · Cited by 1
Perspectives of inpatient neurological rehabilitation in elderly patients
MUREȘAN, D. A., Stănescu, I., Bulboacă, A. E., Fodor, D. M., & BULBOACĂ, A. I. (2019) · Balneo Research Journal · doi:10.12680/balneo.2019.287 · Cited by 1
Combatting Sedentary Lifestyles: Can Exercise Prescription in the Emergency Department Lead to Behavioral Change in Patients?
Milne, F., Leech-Porter, K., Atkinson, P., Lewis, D., Fraser, J. M., & Hull, S. (2020) · Cureus · doi:10.7759/cureus.7071 · Cited by 1
Association between types of leisure-time physical activity and falls in the older adults: a population-based study
de Figueiredo, J. A., Lopes, C. D. S., do Vale, W. D. S., Oliveira, B. R. R., Neto, G. D. A. M., de León, A. P., Pancoti, B. M., Penna, T. A., & de Oliveira, A. J. (2022) · Sport Sciences for Health · doi:10.1007/s11332-021-00835-7 · Cited by 1
Statistical Reproducibility of Meta-Analysis for Medical Mask Use in Community Settings to Prevent Airborne Respiratory Virus Infection
Young, S. S., & Kindzierski, W. B. (2023) · International Journal of Statistics and Probability · doi:10.5539/ijsp.v12n4p1 · Cited by 1
Evaluation of a Strength-Training Program on Clinical Outcomes in Older Adults
Burtscher, J., Millet, G. P., & Burtscher, M. (2021) · JAMA · doi:10.1001/jama.2021.0337 · Cited by 1
Exploring the microbiome’s potential role in severe COVID-19: possible implications for prevention and treatmentPreprint
Waterhouse, J. C. (2020) · doi:10.22541/au.158758665.58622495 · Cited by 1
Osteoporosis: burden, diagnosis, and management
Reginster, J., & Bruyère, O. (2022) · Pathy's Principles and Practice of Geriatric Medicine · doi:10.1002/9781119484288.ch77 · Cited by 1
Falls in Older Persons
Cendoroglo, M. S., & Nascimento, N. A. P. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.11435-7
Ostéoporose post-ménopausique en 2019
Roux, C. (2019) · Revue du Rhumatisme · doi:10.1016/s1169-8330(19)30352-7
Evaluation of a Meta-Analysis of Ambient Air Quality as a Risk Factor for Asthma Exacerbation
Kindzierski, W. B., Young, S. S., Meyer, T. G., & Dunn, J. D. (2021) · Journal of Respiration · doi:10.3390/jor1030017 · Cited by 13
“Another set of p-value plots of metaanalysis datasets for large numbers of base papers (n > 65) are illustrated in SI 5 (true null relationship [84]) and SI 6 (true relationship [85]).”
Background
Exercise and other physical therapy interventions in the management of osteoporosis
Giangregorio, L., & Katzman, W. B. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-813073-5.00069-1
Reliability of meta-analysis of an association between ambient air quality and development of asthma later in life
Young, S. S., Cheng, K.-C., Chen, J., Chen, S., & Kindzierski, W. B. (2020) · arXiv (Cornell University) · doi:10.48550/arxiv.2010.10922
Reminiscence‐tied cycling technology in long‐term care: A feasibility study
Zorz, S., Dellaire, S., Reilly, K., Wilson‐Sanchez, J., Rodriguez, R. A., & Campbell, T. M. (2021) · Journal of the American Geriatrics Society · doi:10.1111/jgs.17307
INCLUSÃO DE PESSOAS COM DEFICIÊNCIA E ESPORTE PARALÍMPICO
de Souza, D. M., Monteiro, C. E. L., Júnior, C. M. A. L., Lugão, E. C., Costa, F. B., Dantas, K. B. A., & Carvalho, P. E. (2021) · doi:10.22533/at.ed.2272107064
CONDICIONAMENTO FÍSICO, AUTONOMIA FUNCIONAL E QUALIDADE DE VIDA EM IDOSOS
Pernambuco, C. S., Scartoni, F. R., Miranda, F. B., Figueira, H. A., & Cortez, A. C. L. (2021) · doi:10.22533/at.ed.2272107062
NEUROCIÊNCIA DO EXERCÍCIO E SAÚDE MENTAL
Ferreira, C. V., & Júnior, E. F. D. S. (2021) · doi:10.22533/at.ed.2272107061
EXERCÍCIO E DOENÇAS CRÔNICAS NÃO TRANSMISSÍVEIS
Guimarães, A. C., Campos, C. A. M. D. S., Albuquerque, C. B., de Jesus, E. V., Brandão, P. P., da Cruz, I. D. S., de Abreu, G. R., & Bezerra, J. C. P. (2021) · doi:10.22533/at.ed.2272107068
EXERCÍCIOS FÍSICOS PARA DENSIDADE MINERAL ÓSSEA, SAÚDE E RISCO DE QUEDA EM IDOSOS
de Figueirêdo, D. L., da Costa, L. F. G. R., Santos, C. A. D. S., Galiasso, C. A. F., & Borba-Pinheiro, C. J. (2021) · doi:10.22533/at.ed.2272107065
DEPENDÊNCIA QUÍMICA E EXERCICIO FÍSICO
da Costa, C. C. V., Bastos, C. L. B., Silva, D. M., Cavalcante, E. M. N., da Costa, F. D., Martins, J. D. O., Gonçalves, L. C., Souza, L. M. V., Coelho, R. D. C. C., Azevedo, V. D. P., et al. (2021) · doi:10.22533/at.ed.22721070610
SAÚDE, PERFORMANCE E DESENVOLVIMENTO HUMANO
Calomeni, M. R., Lopes, T. C., de Oliveira, A. L. B., & Dantas, E. H. M. (2021) · doi:10.22533/at.ed.2272107067
EXERCÍCIO FÍSICO E DOENÇAS AUTOIMUNES
dos Santos, C. K. A., Masi, F. D., Regazzi, I. C. R., Alves, J. C. C., & Ribeiro, L. C. P. (2021) · doi:10.22533/at.ed.2272107063
CONDICIONAMENTO FÍSICO, SAÚDE E QUALIDADE DE VIDA
Dantas, E. H. M., de Souza, C. J. P., Ramos, L. F. D. S., & Leal, S. M. D. O. (2021) · doi:10.22533/at.ed.2272107066
Resistance Training in Older Adults
Sañudo, B., & Rogers, M. E. (2021) · Lecture notes in bioengineering · doi:10.1007/978-3-030-81989-7_16
"Una trottolina che gira, senza saper perché". Scheda per Pirandello poeta
Elli, E. (2012)
The Role of Physical Activity in Healthy Ageing: An Overview for the Family Physician
Smith, L., Bruyère, O., Hoedebecke, K. L., & Loosemore, M. (2021) · Practical issues in geriatrics · doi:10.1007/978-3-030-78923-7_5
Comprehensive Geriatric Assessment
Dharmarajan, T. S. (2021) · Springer eBooks · doi:10.1007/978-3-319-90761-1_8-2
Long-term exercise programmes reduce falls and injuries in older adults
(2019) · doi:10.3310/signal-000749
Quality and Safety in the Literature: September 2022
Burke, A., Gupta, A. B., & Houchens, N. (2022) · BMJ Quality & Safety · doi:10.1136/bmjqs-2022-015160
Drugs in geriatric patient
Marineci, C. D. (2022) · Farmacist ro · doi:10.26416/farm.207.4.2022.7088
Physical Exercise
Izquierdo, M. (2023) · Springer eBooks · doi:10.1007/978-3-030-01782-8_109-1
Testing the reliability of the Downton Fall Risk Index for predicting incident falls in community-dwelling older adults. A prospective population-based study.
Brutto, Ó. H. D., Mera, R. M., Rumbea, D. A., Recalde, B. Y., & Sedler, M. J. (2023) · Revista Ecuatoriana de Neurologia · doi:10.46997/revecuatneurol31300016
Ejercicio multicomponente en el adulto mayor y su efecto en el síndrome de fragilidad
Ramos, M. S., Andrade, E. P., & Pimentel, L. P. (2023) · ALERTA Revista Científica del Instituto Nacional de Salud · doi:10.5377/alerta.v6i2.15613 · Cited by 3
FMUPorto - Summaries and comments
Paiva, B. P. (2023) · Revista de Medicina Desportiva informa · doi:10.23911/fmup_2023_nov
The relationship between self-rated health and subsequent health outcomes over the decades among older Individuals in the United States
Wong, S. J. K. (2023) · doi:10.32657/10356/173234
Physical Exercise
Izquierdo, M. (2024) · Springer eBooks · doi:10.1007/978-3-030-74720-6_109
Family Medicine
Švab, I., Klemenc–Ketiš, Z., & Homar, V. (2024) · doi:10.18690/um.mf.1.2024
Association of physical activity with fractures in kidney transplant recipients: A Korean nationwide cohort study
Kim, S., Jung, J., Lee, K., Jeon, J., Shin, D. W., Jang, H. R., Lee, J. E., Han, K., & Huh, W. (2024) · Clinical Transplantation · doi:10.1111/ctr.15308
Pharmacological treatment of osteoporosis and prevention of fractures: recommendations for clinical practice
Zikán, V. (2024) · Vnitřní lékařství · doi:10.36290/vnl.2024.028
Exercise Strategies for Improving Health Outcomes in Older Adults with Comorbidities: The Role of Vivifrail Tailored-Multicomponent Training
Izquierdo, M. (2024) · Springer eBooks · doi:10.1007/978-3-031-57361-3_27
Queda em idosos e fatores associados: estudo de base populacional em Criciúma - SC
de Boit, F. S. D., Schäfer, A. A., Dallazen, C., Burato, L., Miranda, V. I. A., Quadra, M. R., & Meller, F. D. O. (2024) · Contribuciones a las Ciencias Sociales · doi:10.55905/revconv.17n.6-015
Prävention bei geriatrischen Patientinnen und Patienten in der Allgemeinmedizin
Glehr, R. C. (2024) · Zeitschrift für Gerontologie und Geriatrie · doi:10.1007/s00391-024-02358-5
Testing for Elderly Fragility: A Valuable Public Policy and an Opportunity for Postal Operators
Borsenberger, C., Cremer, H., Joram, D., Lozachmeur, J., & Malavolti, E. (2024) · Topics in Regulatory Economics and Policy · doi:10.1007/978-3-031-65599-9_19
Mitigating Deconditioning in Nursing Homes: A Feasibility and Acceptability Study of the PUSH Tool (Promoting the Autonomy through Exercise in Nursing Home)
Buckinx, F., Libin, V., Peyrusqué, É., Aubertin‐Leheudre, M., & Bruyère, O. (2024) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2024.105381
Associations between Starting to Exercise in Later Life and Survival among Older Adults: a Nationwide, Community-based, Prospective Cohort Study in China
Ruan, H., Wang, Z., Wang, K., Zhang, M., & He, S. (2025) · Sports Medicine - Open · doi:10.1186/s40798-025-00851-8
“For instance, exercise—a subcategory of physical activity that is planned, structured, repetitive, and purposeful [3] —not only enhances muscle strength and bone mineral density [11–13], but also reduces the risk of falls in older adults [14].”
Multicomponent Exercise Strategies for Improving Health Outcomes
Izquierdo, M. (2025) · Nutrition and health · doi:10.1007/978-3-031-87441-3_12
Multiple correspondence analysis on intensity of elderly sports participation in China
Zhu, L., Jiang, S., Zhao, C., Feng, Y., & Kang, J. (2025) · Scientific Reports · doi:10.1038/s41598-025-11562-1
“Some researches 16,17 explored their interaction.”
Balance declines with age, but exercise can help stave off some of the risk of falling
Papa, E. V. (2023) · doi:10.64628/aai.7ac5mmy7q
The effect of psychosocial and healthcare interventions on hospitalisation in people with dementia: an umbrella reviewPreprint
Howard, C., Fernández‐Sanlés, A., Abukar, N., Davis, D. H. J., Goodman, C. M., Gupta, S. K., Handley, M., Mukadam, N., Riddington, C., Walters, K. R., et al. (2025) · medRxiv · doi:10.1101/2025.10.13.25337873
Additional file 1 of Effect of a multicomponent exercise program and cognitive stimulation (VIVIFRAIL-COGN) on falls in frail community older persons with high risk of falls: study protocol for a randomized multicenter control trial
Sánchez‐Sánchez, J. L., Udina, C., Medina‐Rincón, A., Víctor, M. E., Bartolomé-Martín, I., Moral-Cuesta, D., Marín‐Epelde, I., Ramón‐Espinoza, F., Latorre, M. S., Idoate, F., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20364888
Additional file 3 of Effect of a multicomponent exercise program and cognitive stimulation (VIVIFRAIL-COGN) on falls in frail community older persons with high risk of falls: study protocol for a randomized multicenter control trial
Sánchez‐Sánchez, J. L., Udina, C., Medina‐Rincón, A., Víctor, M. E., Bartolomé-Martín, I., Moral-Cuesta, D., Marín‐Epelde, I., Ramón‐Espinoza, F., Latorre, M. S., Idoate, F., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20364894
Additional file 1 of Usual physical activity and subsequent hospital usage over 20 years in a general population: the EPIC-Norfolk cohort
Luben, R., Hayat, S., Wareham, N. J., Pharoah, P., & Khaw, K. (2020) · Figshare · doi:10.6084/m9.figshare.12262025
Additional file 1 of Physical activity as a risk or protective factor for falls and fall-related fractures in non-frail and frail older adults: a longitudinal study
van Gameren, M., Hoogendijk, E. O., van Schoor, N. M., Bossen, D., Visser, B., Bosmans, J. E., & Pijnappels, M. A. G. M. (2022) · Figshare · doi:10.6084/m9.figshare.20545729
Additional file 1 of Effectiveness of fall prevention interventions in residential aged care and community settings: an umbrella review
Meulenbroeks, I., Mercado, C., Gates, P., Nguyen, A., Seaman, K. L., Wabe, N., Silva, S. M., Zheng, W. Y., Debono, D., & Westbrook, J. (2024) · Figshare · doi:10.6084/m9.figshare.26669748
Additional file 2 of Effect of a multicomponent exercise program and cognitive stimulation (VIVIFRAIL-COGN) on falls in frail community older persons with high risk of falls: study protocol for a randomized multicenter control trial
Sánchez‐Sánchez, J. L., Udina, C., Medina‐Rincón, A., Víctor, M. E., Bartolomé-Martín, I., Moral-Cuesta, D., Marín‐Epelde, I., Ramón‐Espinoza, F., Latorre, M. S., Idoate, F., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20364891
Additional file 4 of Effect of a multicomponent exercise program and cognitive stimulation (VIVIFRAIL-COGN) on falls in frail community older persons with high risk of falls: study protocol for a randomized multicenter control trial
Sánchez‐Sánchez, J. L., Udina, C., Medina‐Rincón, A., Víctor, M. E., Bartolomé-Martín, I., Moral-Cuesta, D., Marín‐Epelde, I., Ramón‐Espinoza, F., Latorre, M. S., Idoate, F., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20364897
THE IMPACT OF PHYSICAL ACTIVITY ON DEMENTIA IN ELDERLY AGE
Starosta, B., Brzychcy, B., Gajda, Z., Pelczar, M., Brzychcy, K., Paks, K., Jench, E., Musialik, N., & Magiera, M. (2025) · International Journal of Innovative Technologies in Social Science · doi:10.31435/ijitss.3(47).2025.3857
Geriatric Health: Research to Policy
Sinha, A., Bhardwaj, P., & Pati, S. (2025) · Indian Journal of Community Medicine · doi:10.4103/ijcm.ijcm_518_25
The combined effect of exercise program and oral vitamin D supplementation on the rate of falls and injurious falls in aged 70 years and older: a systematic review and meta-analysis
Pourmanaf, H., Sari-Sarraf, V., Rashidpour, A., & Ghojazadeh, M. (2026) · Sport Sciences for Health · doi:10.1007/s11332-026-01646-4
Low Gait Speed as a Risk Factor for Long-Term Mortality in the Hospitalized Elderly Patients
Borges, R. C., Correa, D. I., Silva, M. D. S., Gomes, A. D. S., & Borghi, S. M. (2025) · Physical & Occupational Therapy In Geriatrics · doi:10.1080/02703181.2025.2530988
“36 Specifically, gait speeds below 0.8 meters per second (m/s) have been consistently associated with an increased risk of adverse events, such as falls, prolonged hospitalizations, and mortality.”
Influential
Outcomes of older adult physical activity participation that matter to health care professionals
Mackey, D. C., & Mackey, D. C. (2026) · Innovation in Aging · doi:10.1093/geroni/igag020
“…suggests that certain physical activity interventions can reduce the incidence and severity of falls, there is still uncertainty about the efficacy of some types of exercise interventions, such as walking programs, due to limited evidence (de Souto Barreto et al., 2019; Sherrington et al., 2019).”
Lifestyle factors, including physical activity status, associated with fragility fractures and falls: a cross-sectional study
Iwamae, M., Tamai, K., Ikebuchi, M., Takahashi, S., Higuchi, Y., Uemura, K., Ueda, M., Okazaki, K., Yokoyama, H., Kawabata, H., et al. (2026) · BMC Geriatrics · doi:10.1186/s12877-026-07344-7
“In particular, multicomponent exercise programs that include balance, strength, and endurance training are effective [51].”
Déterminants de la perte osseuse au cours de déclins fonctionnels multiples ˸ pour une approche intégrée : Caractérisation des déterminants de perte osseuse chez l'insuffisant rénal et l'obèse opéré de chirurgie bariatrique
Cailleaux, P. (2022) · theses.fr (ABES) · doi:10.70675/c86911ecz3e22z449fzb988ze55d8c9e7ae8
The effect of psychosocial and healthcare interventions on reducing hospitalization in people with dementia: an umbrella review
Howard, C., Fernández‐Sanlés, A., Abukar, N., Davis, D. H. J., Goodman, C. M., Gupta, S., Handley, M., Mukadam, N., Riddington, C., Walters, K. R., et al. (2026) · Alzheimer s & Dementia · doi:10.1002/alz.71323 · Cited by 1
“36,133 However, in our analysis of studies of PwD, we found strong evidence that these programs did not reduce hospitalization, suggesting that there may be additional components required beyond general exercise programs to reduce hospitalization in PwD. Studies of general older adult populations…”
Preventing Hip (Proximal Femoral) Fractures: An Evidence-Based Review for Clinicians
Kawai, T., Okuzu, Y., Takaoka, Y., Natsume, D., & Matsuda, S. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15166148 · Cited by 1
“Long-term exercise programs reduce overall falls and injurious falls, and they probably reduce fracture incidence as well, although most individual trials remain underpowered for hip fracture specifically [16].”
Multidomain changes in clinical outcomes after 12 weeks of resistance-based exercise training in healthy older adults: a four‑domain framework for identifying non‑responders
Matko, Š., Strasser, B., Steinecker-Frohnwieser, B., Stamm, T., Kern, H., Löfler, S., Hochenwarter, S., Prüfer, F., Unger, A., Tirpáková, V., et al. (2026) · European Geriatric Medicine · doi:10.1007/s41999-026-01614-8
Osteoporosis
Slovik, D. M. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-23516-0.00138-0

Authors: de Souto Barreto, P., Rolland, Y., Vellas, B., & Maltais, M.
Affiliations: Gerontopole of Toulouse, Institute of Ageing, Toulouse University Hospital (CHU Toulouse), Toulouse, France
Université Toulouse III - Paul Sabatier (FR)
Centre Hospitalier Universitaire de Toulouse (FR)
ORCID: Rolland, Yves
Vellas, Bruno
Maltais, Mathieu
Venue: JAMA Internal Medicine
Publisher: American Medical Association (AMA)
Published: 2019-03-01
Volume: 179
Issue: 3
Pages: 394
ISSN: 2168-6106 (ISSN-L)
DOI: 10.1001/jamainternmed.2018.5406
PMC: PMC6439708
OpenAlex: W2906707737
Cited by: 186
References: 80
Citations by year: 2026: 11 · 2025: 23 · 2024: 24 · 2023: 27 · 2022: 32 · 2021: 31 · 2020: 20 · 2019: 17
FWCI: 3.30
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: JAMA Internal Medicine (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
HAL (submittedVersion)
Topics: Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
Keywords: long-term exercise training, older adults, falls, injurious falls, fracture, hospitalization, mortality, multicomponent exercise, resistance training, balance training, aerobic exercise, exercise safety, fall risk reduction, exercise frequency, exercise duration, exercise dose-response, exercise adherence facilitators
MeSH terms: Accidental Falls, Aged, Hospitalization, Humans, Mortality, Exercise, Randomized Controlled Trials as Topic, Fractures, Bone

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Association of Long-term Exercise Training With Risk of Falls, Fractures, Hospitalizations, and Mortality in Older Adults: A Systematic Review and Meta-analysis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks