Association of Chronic Low-grade Inflammation With Risk of Alzheimer Disease in ApoE4 Carriers
Tao, Qiushan, Ang, Ting Fang Alvin, DeCarli, Charles, Auerbach, Sanford H., Devine, Sheral, Stein, Thor D., Zhang, Xiaoling, Massaro, Joseph, Au, Rhoda, Qiu, Wei Qiao·2018·JAMA Network Open
Cited by (240)
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- Author Response: Impact of C-Reactive Protein on Cognition and Alzheimer Disease Biomarkers in Homozygous APOE ɛ4 CarriersWei Qiao Qiu, Qiushan Tao, Samia C. Akhter‐Khan · 2022 · Neurology
- APOE genotype or presence of brain amyloid alters the plasma proteome in cognitively normal, elderly subjectsSarah M. Philippi, Kailash BP, Towfique Raj, Joseph M. Castellano · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Effect of methanol aqueous extract of Satureja montana and two of its bioactive components on memory in ratsN. Vilmosh, Delian P. Delev, Ilia Kostadinov, H. Zlatanova, M. Georgieva-Kotetarova, I. Kandilarov, Ivanka I. Kostadinova · 2023 · Tropical Journal of Pharmaceutical Research
- Glial Cells in Alzheimer’s DiseaseMarie Louise Verkerke · 2023 · Utrecht University Repository (Utrecht University)
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- Decreased interleukin-8 levels in the peripheral blood of Alzheimer’s patientsFrancisco Ros‐Bernal, María Dolores Martínez Lozano, Javier Arnau, Joaquín Martínez‐López, Alejandro Vericat, Rafael Sánchez, Javier S. Burgos · 2024 · medRxiv
- The effect of C-reactive protein and interleukin-3 on mild cognitive impairment with APOE ɛ4Xinyi Yang, Lei Chi, Meizhao Qiao, A.C. Huang, Huimin Wu, Shanshan Chen, Jia Fan, Xingjian Lin, Jiu Chen, Alzheimer’s Disease Neuroimaging Initiative · 2025 · Journal of Alzheimer s Disease
- ApoE and Intestinal Mucosal ImmunityOrleâncio Gomes Ripardo de Azevedo, Gerly Anne de Castro Brito, Cirle Alcantara Warren, Reinaldo B. Oriá · 2025 · Springer eBooks
- Apolipoprotein E4 Carriers as Clinical Trial SubjectsCarr J. Smith, John Wesson Ashford, Thomas A. Perfetti · 2025 · Springer eBooks
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- Additional file 8 of Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4Shaowei Wang, Li, Boyang, Victoria A. Solomon, Alfred Nji Fonteh, Rapoport, Stanley I., Bennett, David A., Zoe Arvanitakis, Chui, Helena C., Patrick M. Sullivan, Hussein N. Yassine · 2022 · Figshare
- Additional file 7 of Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4Shaowei Wang, Li, Boyang, Victoria A. Solomon, Alfred Nji Fonteh, Rapoport, Stanley I., Bennett, David A., Zoe Arvanitakis, Chui, Helena C., Patrick M. Sullivan, Hussein N. Yassine · 2022 · Figshare
- Additional file 1 of Comparing regional brain uptake of incretin receptor agonists after intranasal delivery in CD-1 mice and the APP/PS1 mouse model of Alzheimer’s diseaseAbdulhameed, Noor, Alice Babin, Hansen, Kim, Riley R. Weaver, William A. Banks, Konrad Talbot, Elizabeth M. Rhea · 2024 · Figshare
- Additional file 1 of Aging gene signature of memory CD8+ T cells is associated with neurocognitive functioning in Alzheimer’s diseaseJuan Joseph Young, Park, Hong-Jai, Kim, Minhyung, Jennefer Par‐Young, Hugh H. Bartlett, Kim, Hye Sun, Serhan Ünlü, Lais Osmani, Min Sun Shin, Bucala, Richard et al. · 2023 · Figshare
- Additional file 6 of Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4Shaowei Wang, Li, Boyang, Victoria A. Solomon, Alfred Nji Fonteh, Rapoport, Stanley I., Bennett, David A., Zoe Arvanitakis, Chui, Helena C., Carol A. Miller, Sullivan, Patrick M. et al. · 2021 · Figshare
- Additional file 3 of Comparing regional brain uptake of incretin receptor agonists after intranasal delivery in CD-1 mice and the APP/PS1 mouse model of Alzheimer’s diseaseAbdulhameed, Noor, Alice Babin, Hansen, Kim, Riley R. Weaver, William A. Banks, Konrad Talbot, Elizabeth M. Rhea · 2024 · Figshare
- Additional file 2 of Comparing regional brain uptake of incretin receptor agonists after intranasal delivery in CD-1 mice and the APP/PS1 mouse model of Alzheimer’s diseaseAbdulhameed, Noor, Alice Babin, Hansen, Kim, Riley R. Weaver, William A. Banks, Konrad Talbot, Elizabeth M. Rhea · 2024 · Figshare
- Additional file 2 of Aging gene signature of memory CD8+ T cells is associated with neurocognitive functioning in Alzheimer’s diseaseJuan Joseph Young, Park, Hong-Jai, Kim, Minhyung, Jennefer Par‐Young, Hugh H. Bartlett, Kim, Hye Sun, Serhan Ünlü, Lais Osmani, Min Sun Shin, Bucala, Richard et al. · 2024 · Figshare
- Influence of APOE4 Genotypes on Nutrient–Cognition Relationship in Taiwanese Older Adults: Longitudinal Findings from the HALSTRai-Hua Lai, Shiu-Ju Yang, Pei-Yi Hsu, Yi‐Chung Chen, Shu‐Chun Chuang, Chih-Cheng Hsu, Chao A.gnes Hsiung, Fang-Lin Kuo · 2025 · Nutrients
- Cortical mean diffusivity detects early age-related changes and associates with cognition and plasma biomarkersOriol Perera‐Cruz, Cristina Solé‐Padullés, Lídia Mulet‐Pons, María R. Cabello‐Toscano, Rachel M. Morse, Kilian Abellaneda‐Pérez, Ruben Perellón‐Alfonso, Gabriele Cattaneo, Javier Solana Sánchez, Vanessa Alviarez‐Schulze et al. · 2026 · Brain Communications
- Circulating C-reactive protein influences polygenic risk of inflammatory genes expressed in brain endothelia for Alzheimer’s diseaseJinghan Huang, Habbiburr Rehman, Chinh Doan, Thor D. Stein, Jesse Mez, Ting Fang Alvin Ang, Qiushan Tao, Rhoda Au, Lindsay A. Farrer, Xiaoling Zhang et al. · 2026 · Neurobiology of Disease
- A comprehensive understanding of HDL-associated apolipoproteins: future potential biomarker in sepsisJingjing Ning, Tiantian Liu, Yilin Zhao, C. Wang · 2026 · Expert Review of Molecular Diagnostics
- Apolipoprotein E, malnutrition, and neurodegenerative riskGabriella Cunha Vieira Ciurleo, Camila Gonçalves Monteiro Carvalho, Raul Sousa Freitas, Reinaldo B. Oriá · 2026 · Elsevier eBooks
- Divergent biological consequences of APOE isoforms across industrialized and non-industrial environmentsMarina M. Watowich, Rachel M. Petersen, Layla Brassington, Audrey M. Arner, Grace Rodenberg, Tan Bee Ting A P Tan Boon Huat, Kar Lye Tam, Em Schellenberg, Izandis bin Mohd Sayed, Echwa John et al. · 2026 · PLoS Genetics
- Is there a role for apolipoprotein E in perinatal brain injury?Savina Abraham-Pol, Ertan Mayatepek, Mark Dzietko · 2026 · Molecular and Cellular Pediatrics
- Brain Neuroplasticity and Alzheimer’s Disease Prevention: Health Considerations for Those with an ApoE-ε4 GeneJohn Wesson Ashford, Carr J. Smith, Reinaldo B. Oriá · 2026 · Springer eBooks
- Decreased interleukin-8 levels in the peripheral blood of Alzheimer's disease patientsFrancisco Ros, María Dolores Martínez Lozano, Javier Arnau, Jacobo Martínez, Alejandro Vericat, Rafael Madariaga Sánchez, Javier S. Burgos · 2026 · Journal of Alzheimer s Disease
- Longitudinal Brain Atrophy Patterns in Dementia and Cognitive Decline: the Framingham Heart StudyHabbiburr Rehman, Qiushan Tao, Jackson C. Nolan, Nuzulul Kurniansyah, Ting Fang Alvin Ang, Paul K. Crane, Shubhabrata Mukherjee, Andrew J. Saykin, Emily H. Trittschuh, Thor D. Stein et al. · 2026 · medRxiv
- Brain Neuroplasticity and Alzheimer’s Disease Prevention: Health Considerations for Those with an ApoE-ε4 GeneJohn Wesson Ashford, Carr J. Smith, Reinaldo B. Oriá · 2026 · Springer eBooks
- Impact of CKD and COPD co-existence on mortality, vascular dementia, and Alzheimer’s dementia; a comparative cohort studyLino Merlino, Francesco Rainone, James Tollitt, Rajkumar Chinnadurai, Francesca Rusconi, Gema Hernandez, Graziana G Battini, Paolo M. Colombo, Stuart Stewart, Ross A. Dunne et al. · 2026 · BMC Nephrology
- Chronic low-grade inflammation, genetic susceptibility, and the risk of multiple sclerosis: a prospective cohort studyYizhou Cai, Yujia Bao, Yifan Li, Jiawei Gu, Qingqing Ran, Yibin Zhou, Linjuan Dong, Dunjia Wang, Xia Zhao, Yuping Cheng et al. · 2026 · Frontiers in Immunology
- Associations of peripheral inflammation with hippocampal atrophy in Alzheimer's diseaseHongsheng Xie, Yuhao Li, Ruoqiu Gan, Ziru Zhao, Qin Chen, Zhiyun Jia · 2026 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
- CSF neuroinflammatory biomarkers are associated with amyloid-β42/40, tau pathology, and cognitive impairment across the Alzheimer’s disease spectrumMubarak Alruwaili, Areej Ahmed Turkistani, Sireen Abdul Rahim Shilbayeh, Dahlia Soleman A. Mirdad, Marwa Fareed Almulhim, Saud Alnaaim, Muhannad Almubarak, Alzheimer’s Disease Neuroimaging Initiative · 2026 · Immunologic Research