Association of a Polygenic Risk Score With Breast Cancer Among Women Carriers of High- and Moderate-Risk Breast Cancer Genes

Gallagher, Shannon, Hughes, Elisha, Wagner, Susanne, Tshiaba, Placede, Rosenthal, Eric, Roa, Benjamin B., Kurian, Allison W., Domchek, Susan M. +6 more·2020·JAMA Network Open
DOI 10.1001/jamanetworkopen.2020.8501

Cited by (137)

Items 101–137 of 137

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  12. Risk stratification by genomic information: now and in the future
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  17. Estudio combinado de marcadores fenotípicos y genotípicos para la evaluación del riesgo individualizado a desarrollar cáncer de mama
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  18. Addressing overlapping sample challenges in genome-wide association studies: Meta-reductive approach
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  19. Breast and endometrial cancer susceptibility, genome-wide haplotype association studies
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  20. Genetic and lifestyle modifiers of haemochromatosis-related clinical outcomes in HFE C282Y homozygotes: prospective cohort study in UK Biobank
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  21. Polygenic risk scores for breast cancer: Progress, challenges, and clinical integration
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  22. Polygenic risk scores in breast cancer: A systematic review of predictive utility, clinical applications, and future directions
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  23. Polygenic risk scores to refine Breast cancer screening and prevention strategies
    E Roberts, Nicola Flaum, Sacha Jon Howell, D. Gareth Evans · 2025 · Personalized Medicine
  24. Integrative Gene-Centric Analysis Reveals Cellular Pathways Associated with Heritable Breast Cancer Predisposition
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  25. Additional file 1 of Design and user experience testing of a polygenic score report: a qualitative study of prospective users
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  26. Additional file 2 of Design and user experience testing of a polygenic score report: a qualitative study of prospective users
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  27. Additional file 3 of Polygenic risk scores indicate extreme ages at onset of breast cancer in female BRCA1/2 pathogenic variant carriers
    Julika Borde, Laitman, Yael, Britta Blümcke, Niederacher, Dieter, Konstantin Weber‐Lassalle, Sutter, Christian, Rump, Andreas, Arnold, Norbert, Wang-Gohrke, Shan, Horváth, Judit et al. · 2022 · Figshare
  28. Additional file 1 of Polygenic risk scores indicate extreme ages at onset of breast cancer in female BRCA1/2 pathogenic variant carriers
    Julika Borde, Laitman, Yael, Britta Blümcke, Niederacher, Dieter, Konstantin Weber‐Lassalle, Sutter, Christian, Rump, Andreas, Arnold, Norbert, Wang-Gohrke, Shan, Jane Horvath et al. · 2022 · Figshare
  29. Association of high and moderate penetrance monogenic variants, polygenic risk, and family history with breast cancer in an ancestrally diverse population
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  30. The impact of breast cancer polygenic risk score disclosure on decisional conflict around risk-reducing mastectomy in women with pathogenic BRCA1/2 variants
    Giulia Ongaro, Caroline Salafia, Rania Sheikh, Elizabeth Schofield, Dana Farengo Clark, Jessica Ebrahimzadeh, Anu B. Chittenden, Jill E. Stopfer, Jamie Brower, Heather Symecko et al. · 2026 · Genetics in Medicine
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  32. Polygenic risk scores in cancer
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  33. The co-design, development, and preliminary evaluation of a comprehensive breast cancer risk report incorporating polygenic risk information.
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  36. Rethinking Hereditary Cancer Testing Eligibility: A Five-Domain Framework Beyond Family History Gating
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  37. Rare variant burden complements polygenic risk in breast cancer and is associated with earlier diagnosis
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