Head-to-Head Comparison of 8 Plasma Amyloid-β 42/40 Assays in Alzheimer Disease

Janelidze, Shorena; Teunissen, Charlotte E.; Zetterberg, Henrik; Allué, José Antonio; Sarasa, Leticia; Eichenlaub, Udo; Bittner, Tobias; Ovod, Vitaliy; Verberk, Inge M. W.; Toba, Kenji; Nakamura, Akinori; Bateman, Randall J.; Blennow, Kaj; Hansson, Oskar

doi:10.1001/jamaneurol.2021.3180

Head-to-Head Comparison of 8 Plasma Amyloid-β 42/40 Assays in Alzheimer Disease

Importance Blood-based tests for brain amyloid-β (Aβ) pathology are needed for widespread implementation of Alzheimer disease (AD) biomarkers in clinical care and to facilitate patient screening and monitoring of treatment responses in clinical trials. Objective To compare the performance of plas…