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Candida albicans homologue ofGGP1/GAS1 gene is functional inSaccharomyces cerevisiae and contains the determinants for glycosylphosphatidylinositol attachment
Abstract
The nucleotide sequence of a 43 118 bp fragment from chromosome VII of Saccharomyces cerevisiae has been determined and analysed. The fragment originates from the right arm of chromosome VII. It starts approximately 11 kb centromere-proximal to the per54 marker and ends in the middle of the PFK1 gene. The sequence contains a small nuclear RNA gene (SNR7) and 29 open reading frames (ORFs) larger than 100 amino acids. Six of these were completely internal to or partially overlapped other ORFs. Six previously described genes, YLM9/MRPL9, CRM1, DIE2, SMI1, PHO81 and YHB4, were mapped to this region in addition to pet54 and PFK1. Of the remaining 17 ORFs, four showed homology with other S. cerevisiae genes and four, including one of the partially overlapping ORFs, with genes from other organisms. Eight ORFs had no homology with any sequence in the databases.
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“Phr1p is responsible of glucan remodeling at neutral-alkaline pH and is essential for morphogenesis and virulence.”
From Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling (2016) · cites this paper as [15]
In the citing paper
“Phr1p and Phr2p are highly similar to Saccharomyces cerevisiae Gas1p, they share the same activity in vitro and PHR1 complements gas1Δ mutation [15, 16].”
From Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling (2016) · cites this paper as [15]
In the citing paper
“GAS1, GAS2, and GAS5 are glycosylphosphatidylinositol (GPI)-anchored cell surface proteins [122], which are involved in the production of β-1,3 glucan in C. glabrata [123].”
From Candida glabrata Biofilms: How Far Have We Come? (2017) · cites this paper as [122]
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Metadata
- Authors
- Vai, M., Orlandi, I., Cavadini, P., Alberghina, L., & Popolo, L.
- Venue
- Yeast
- Published
- 1996
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- CoChat. (2026). Citation check: Candida albicans homologue ofGGP1/GAS1 gene is functional inSaccharomyces cerevisiae and contains the determinants for glycosylphosphatidylinositol attachment. https://app.cochat.ai/papers/10.1002/(sici)1097-0061(19960330)12:4
- The paper
- Vai, M., Orlandi, I., Cavadini, P., Alberghina, L., & Popolo, L. (1996). Candida albicans homologue ofGGP1/GAS1 gene is functional inSaccharomyces cerevisiae and contains the determinants for glycosylphosphatidylinositol attachment. Yeast. https://doi.org/10.1002/(sici)1097-0061(19960330)12%3A4
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