The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
LC‐MS Data Processing with MAVEN: A Metabolomic Analysis and Visualization Engine
Open accessAbstract
MAVEN is an open‐source software program for interactive processing of LC‐MS‐based metabolomics data. MAVEN enables rapid and reliable metabolite quantitation from multiple reaction monitoring data or high‐resolution full‐scan mass spectrometry data. It automatically detects and reports peak intensities for isotope‐labeled metabolites. Menu‐driven, click‐based navigation allows visualization of raw and analyzed data. Here we provide a User Guide for MAVEN. Step‐by‐step instructions are provided for data import, peak alignment across samples, identification of metabolites that differ strongly between biological conditions, quantitation and visualization of isotope‐labeling patterns, and export of tables of metabolite‐specific peak intensities. Together, these instructions describe a workflow that allows efficient processing of raw LC‐MS data into a form ready for biological analysis. Curr. Protoc. Bioinform. 37:14.11.1‐14.11.23. © 2012 by John Wiley & Sons, Inc.
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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Dang, L., White, D. W., Gross, S., Bennett, B. D., Bittinger, M. A., Driggers, E. M., Fantin, V. R., Jang, H. G., Jin, S., Keenan, M. C., et al. (2009) · Nature · doi:10.1038/nature08617 · Cited by 4,154
Self-citationShlomi, T., Eisenberg, Y., Sharan, R., & Ruppin, E. (2007) · Molecular Systems Biology · doi:10.1038/msb4100141 · Cited by 254
Metabolomics-driven quantitative analysis of ammonia assimilation in E. coli
Yuan, J., Doucette, C. D., Fowler, W. U., Feng, X., Piazza, M., Rabitz, H. A., Wingreen, N. S., & Rabinowitz, J. D. (2009) · Molecular Systems Biology · doi:10.1038/msb.2009.60 · Cited by 178
Self-citationKinetic flux profiling of nitrogen assimilation in Escherichia coli
Yuan, J., Fowler, W. U., Kimball, E., Lu, W., & Rabinowitz, J. D. (2006) · Nature Chemical Biology · doi:10.1038/nchembio816 · Cited by 125
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Mayers, J. R., Wu, C., Clish, C. B., Kraft, P., Torrence, M. E., Fiske, B. P., Yuan, C., Bao, Y., Townsend, M. K., Tworoger, S. S., et al. (2014) · Nature Medicine · doi:10.1038/nm.3686 · Cited by 649
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Mayers, J. R., Torrence, M. E., Danai, L. V., Papagiannakopoulos, T., Davidson, S. M., Bauer, M. R., Lau, A. N., Ji, B. W., Dixit, P. D., Hosios, A. M., et al. (2016) · Science · doi:10.1126/science.aaf5171 · Cited by 582
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p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression
Moon, S.-H., Huang, C.-H., Houlihan, S. L., Regunath, K., Freed-Pastor, W. A., Morris, J. P., Tschaharganeh, D. F., Kastenhuber, E. R., Barsotti, A. M., Culp-Hill, R., et al. (2019) · Cell · doi:10.1016/j.cell.2018.11.011 · Cited by 435
Metadata
- Authors
- Clasquin, M. F., Melamud, E., & Rabinowitz, J. D.
- Venue
- Current Protocols in Bioinformatics
- Publisher
- Wiley
- Published
- 2012-03
- Volume
- 37
- Issue
- 1
- Pages
- Unit14.11-Unit14.11
- ISSN
- 1934-3396 (ISSN-L)
- 1934-340X
- OpenAlex
- W2149917889
- Cited by
- 514
- References
- 4
- FWCI
- 4.76
- Type
- journal article
- Language
- en
- Open access
- green
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