Clinical Trials: A Methodologic Perspective
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The randomizations in a SMART aim to permit unbiased comparisons between treatment components or their levels at each decision stage in adaptive intervention development.
“the randomizations in a SMART are aimed at permitting unbiased comparisons between treatment components (or their levels) at each decision stage in the development of an AI.”
From Introduction to SMART designs for the development of adaptive interventions: with application to weight loss research (2014) · cites this paper as [75]
Randomization in an RCT or factorial design aims to permit unbiased comparison free of confounding or treatment selection bias.
“just as randomization is aimed at permitting an unbiased comparison (i.e., free of alternative explanations due to confounding or treatment selection bias [75]) between the experimental treatment and a control conditions in an RCT or between different levels of treatment components in a factorial design”
From Introduction to SMART designs for the development of adaptive interventions: with application to weight loss research (2014) · cites this paper as [75]
The minimum sample size for any experimental trial is dictated by the primary aim.
“As is well known, the minimum sample size for any experimental trial is dictated by the primary aim for that trial [75].”
From Introduction to SMART designs for the development of adaptive interventions: with application to weight loss research (2014) · cites this paper as [75]
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Cited by 366
- Authors
- Piantadosi, S.
- Corresponding author
- Piantadosi, Steven
- ORCID
- Piantadosi, Steven
- Venue
- Wiley Series in Probability and Statistics
- Publisher
- Wiley
- Published
- 2005-07-08
- ISSN
- 1940-6347 (ISSN-L)
- OpenAlex
- W4231404455
- Cited by
- 366
- References
- 0
- Citations by year
- 2026: 6 · 2025: 10 · 2024: 10 · 2023: 10 · 2022: 9 · 2021: 11 · 2020: 21 · 2019: 24 · 2018: 15 · 2017: 15 · 2016: 21 · 2015: 31 · 2014: 29 · 2013: 17 · 2012: 37
- FWCI
- 4.38
- Type
- book
- Language
- en
- Open access
- closed
- Locations
- Wiley series in probability and statistics (publishedVersion)
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Physical Sciences › Mathematics › Statistics and Probability › Probability and Statistical Research
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
- Keywords
- clinical trials
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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