The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Compression for venous leg ulcers
Abstract
OBJECTIVES: To assess the effectiveness and cost-effectiveness of compression bandaging and stockings in the treatment of venous leg ulcers. SEARCH STRATEGY: Searches of 19 databases, hand searching of journals, conference proceedings and bibliographies. Manufacturers of compression bandages and stockings and an Advisory Panel were contacted for unpublished studies. SELECTION CRITERIA: Trials that evaluated compression bandaging or stockings, as a treatment for venous leg ulcers. There was no restriction on date or language. Ulcer healing was the primary endpoint. DATA COLLECTION AND ANALYSIS: Details of eligible studies were extracted and summarised using a data extraction sheet. Data extraction was verified by two reviewers independently. MAIN RESULTS: Twenty two trials reporting 24 comparisons were identified. Compression was more effective than no compression (4/6 trials). When multi-layered systems were compared, elastic compression was more effective than non-elastic compression (5 trials). There was no difference in healing rates between 4-layer bandaging and other high compression multi-layered systems (3 trials). There was no difference in healing rates between elastomeric multi-layered systems (4 trials). Multi-layered high compression was more effective than single layer compression (4 trials). Compression stockings were evaluated in two trials. One found a high compression stocking plus a thrombo stocking to be more effective than a short stretch bandage. The second small trial reported no difference between the compression stockings and Unna's boot. There were insufficient data to draw conclusions about the relative cost-effectiveness of different regimens. REVIEWER'S CONCLUSIONS: Compression increases ulcer healing rates compared with no compression. Multi-layered systems are more effective than single-layered systems. High compression is more effective than low compression but there are no clear differences in the effectiveness of different types of high compression.
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Cites
The Handbook of Research Synthesis
Hanka, R. (1994) · BMJ · doi:10.1136/bmj.309.6952.488a · Cited by 1,052
Chronic ulceration of the leg: extent of the problem and provision of care.
Callam, M. J., Ruckley, C. V., Harper, D. R., & Dale, J. J. (1985) · BMJ · doi:10.1136/bmj.290.6485.1855 · Cited by 721
Epidemiology of chronic venous ulcers
Baker, S. R., Stacey, M. C., Jopp-McKay, A. G., Hoskin, S. E., & Thompson, P. J. (1991) · Journal of British Surgery · doi:10.1002/bjs.1800780729 · Cited by 400
A systematic review of compression treatment for venous leg ulcers
Fletcher, A., Cullum, N., & Sheldon, T. A. (1997) · BMJ · doi:10.1136/bmj.315.7108.576 · Cited by 354
Self-citationDeeks, J., Bracken, M. B., Sinclair, J. C., Davies, H. T. O., Tavakoli, M., & Crombie, I. K. (1998) · BMJ · doi:10.1136/bmj.317.7166.1155a · Cited by 226
Prevalence of lower limb ulceration in an urban health district
Lees, T. A., & Lambert, D. (1992) · Journal of British Surgery · doi:10.1002/bjs.1800791015 · Cited by 172
Cordts, P. R., Hanrahan, L. M., Rodriguez, A. A., et al. (1992) · Journal of Vascular Surgery · doi:10.1016/0741-5214(92)90186-c · Cited by 109
The impact of leg ulcers on patients' quality of life.
Charles, H. (1995) · PubMed · Cited by 105
An environment for healing: The role of occlusion
Tempest, M. N. (1986) · Injury · doi:10.1016/0020-1383(86)90340-2 · Cited by 103
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Cited by
Causes, investigation and treatment of leg ulceration
Mekkes, J. R., Loots, M. A. M., Van Der Wal, A. C., & Bos, J. D. (2003) · British Journal of Dermatology · doi:10.1046/j.1365-2133.2003.05222.x · Cited by 381
Compression for preventing recurrence of venous ulcers
Nelson, E. A., Bell-Syer, S. E., Cullum, N. A., & Webster, J. (2000) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002303 · Cited by 314
Self-citationBeidler, S. K., Douillet, C. D., Berndt, D. F., Keagy, B. A., Rich, P. B., & Marston, W. A. (2009) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2008.11.049 · Cited by 223
Chronic Venous Insufficiency and Varicose Veins
Raju, S., & Neglén, P. (2009) · New England Journal of Medicine · doi:10.1056/nejmcp0802444 · Cited by 171
Interventions for helping people adhere to compression treatments for venous leg ulceration
Weller, C. D., Buchbinder, R., & Johnston, R. V. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008378.pub3 · Cited by 114
Metadata
- Authors
- Cullum, N., Nelson, E., Fletcher, A., & Sheldon, T.
- Venue
- The Cochrane Database of Systematic Reviews
- Publisher
- John Wiley & Sons, Ltd
- Published
- 2001-04-23
- Volume
- 90
- Issue
- 2
- Pages
- CD000265-CD000265
- OpenAlex
- W203868290
- Cited by
- 279
- References
- 17
- Type
- reference entry
- Language
- en
- Open access
- closed
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- Cullum, N., Nelson, E., Fletcher, A., & Sheldon, T. (2001). Compression for venous leg ulcers. The Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.cd000265
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
