Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease
Abstract
Background Pulmonary rehabilitation has become a cornerstone in the management of patients with stable Chronic Obstructive Pulmonary Disease (COPD). Systematic reviews have shown large and important clinical effects of pulmonary rehabilitation in these patients. However, in unstable COPD patients who have recently suffered an exacerbation, the effects of pulmonary rehabilitation are less established. Objectives To assess the effects of pulmonary rehabilitation after COPD exacerbations on future hospital admissions (primary outcome) and other patient-important outcomes (mortality, health-related quality of life and exercise capacity). Search strategy Trials were identified from searches of CENTRAL, MEDLINE, EMBASE, PEDRO and the Cochrane Airways Group Register of Trials. Searches were current as of March 2010. Selection criteria Randomized controlled trials comparing pulmonary rehabilitation of any duration after exacerbation of COPD with conventional care. Pulmonary rehabilitation programmes needed to include at least physical exercise. Control groups received conventional community care without rehabilitation. Data collection and analysis We calculated pooled odds ratios and weighted mean differences (MD) using random-effects models. We requested missing data from the authors of the primary studies. Main results We identified nine trials involving 432 patients. Pulmonary rehabilitation significantly reduced hospital admissions (pooled odds ratio 0.22 [95% CI 0.08 to 0.58], n…
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Low completion rates of pulmonary rehabilitation in this study highlight probable sample bias in current post-exacerbation pulmonary rehabilitation research studies.
“The low completion rates of PR in this study highlight the probable sample bias which may exist in current postexacerbation PR research studies [11].”
From Can we identify patients with different illness schema following an acute exacerbation of COPD: A cluster analysis (2014) · cites this paper as [11]
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- Authors
- Puhan, M. A., Gimeno-Santos, E., Scharplatz, M., Troosters, T., Walters, E. H., & Steurer, J.
- Affiliations
- Johns Hopkins University (US)
- KU Leuven (BE)
- University of Tasmania (AU)
- Venue
- Cochrane Database of Systematic Reviews
- Publisher
- John Wiley & Sons, Ltd
- Published
- 2011-10-05
- Issue
- 10
- Pages
- CD005305-CD005305
- ISSN
- 1361-6137 (ISSN-L)
- OpenAlex
- W4252718630
- Cited by
- 379
- References
- 54
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 6 · 2023: 10 · 2022: 15 · 2021: 21 · 2020: 17 · 2019: 15 · 2018: 23 · 2017: 40 · 2016: 55 · 2015: 47 · 2014: 59 · 2013: 45 · 2012: 19
- Type
- reference entry
- Language
- en
- Update notices
- new_version (2016-12-08)
- Open access
- closed
- Locations
- Cochrane Database of Systematic Reviews (publishedVersion)
- PubMed (publishedVersion)
- eCite Digital Repository (University of Tasmania) (submittedVersion)
- ResearchOnline@ND (The University of Notre Dame) (submittedVersion)
- Figshare (submittedVersion)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
- Keywords
- pulmonary rehabilitation, chronic obstructive pulmonary disease, COPD exacerbations, hospitalization, mortality, health-related quality of life, exercise capacity, dyspnea, fatigue, physical activity, St George's Respiratory Questionnaire, Chronic Respiratory Questionnaire, COPD risk stratification, pulmonary hypertension
- MeSH terms
- Health Status, Hospitalization, Humans, Quality of Life, Randomized Controlled Trials as Topic, Exercise Tolerance, Disease Progression, Pulmonary Disease, Chronic Obstructive, Resistance Training
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